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  • 1
    Electronic Resource
    Electronic Resource
    ON THE EVOLUTION OF THE CRANIOCEREBRAL TOPOGRAPHY IN PRIMATES (1969)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 162 (1969), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1969.tb56343.x
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  • 2
    Electronic Resource
    Electronic Resource
    Lagrangian intersections in Contact geometry (1995)
    Springer
    Geometric and functional analysis 5 (1995), S. 244-269 
    Details
    ISSN: 1420-8970
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01895668
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  • 3
    Electronic Resource
    Electronic Resource
    Conservation, evolution, and specificity in cellular control by protein phosphorylation (1996)
    Springer
    Cellular and molecular life sciences 52 (1996), S. 449-454 
    Details
    ISSN: 1420-9071
    Keywords: Protein kinase (cAMP-dependent) ; protein phosphatases ; phosphofructokinase ; Ascaris lumbricoides ; evolution of proteins ; substrate specificity ; regulation of glycolysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract The glycolytic control enzyme phosphofructokinase from the parasitic nematodeAscaris lumbricodies is regulated by reversible phosphorylation. The enzyme is phosphorylated by an atypical cyclic adenosine monophosphate (cAMP)-dependent protein kinase whose substrate specificity deviates from that of the mammalian protein kinase. This variation is explained by structural peculiarities on the surface part of the catalytic groove of the protein kinase. Also, the protein phosphatases responsible for the reversal of phosphorylation appear to act specifically in glycolysis and are different from those participating in regulation of glycogenolysis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01919314
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  • 4
    Electronic Resource
    Electronic Resource
    Erste Erfahrungen mit dem unaufgebohrten AO-Marknagel (UFN) in der Behandlung von Oberschenkelfrakturen (1997)
    Springer
    Der Chirurg 68 (1997), S. 718-726 
    Details
    ISSN: 1433-0385
    Keywords: Key words: Fractures of the femoral shaft ; Unreamed femoral nail (UFN). ; Schlüsselwörter: Oberschenkelschaftfrakturen ; unaufgebohrte Marknagelung (UFN).
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung. Mit den zahlreichen proximalen Verriegelungsmöglichkeiten ermöglicht der in unaufgebohrter Technik eingebrachte AO-Oberschenkelmarknagel (UFN) die chirurgisch minimal-invasive Versorgung der Mehrzahl der Oberschenkelfrakturen. Von Juli 1994 bis August 1996 wurden an unserer Klinik bei 74 Patienten 66 frische Frakturen, 5 Osteolysen bzw. pathologische Frakturen, 2 Verkürzungs- und eine Verlängerungsosteotomie (Monorailverfahren) sowie 3 Pseudarthrosen mit dem UFN stabilisiert. Die Einteilung der Frakturen erfolgte nach der AO-Klassifikation. Unter den Patienten mit frischen Frakturen befanden sich 31 Polytraumatisierte von denen 26 primär am Aufnahmetag und 5 sekundär durchschnittlich nach 5 Tagen versorgt wurden. Der ISS betrug im Durchschnitt 21,8 und der PTS 25,4. Alle 74 Patienten befinden sich unter dauernder Kontrolle, 44 Personen konnten im Zeitraum von 4–18 Monaten nachuntersucht werden. Gemäß unserer klinischen und radiologischen Auswertung erzielten 34 % ein sehr gutes, 36,3 % ein gutes, 20,4 % ein mäßiges und 9 % ein schlechtes Behandlungsergebnis. Die mittlere Konsolidierungszeit lag bei 9,8 Wochen.
    Notes: Summary. The unreamed femoral nail (UFN) system, with its numerous proximal interlocking options, allows a minimal invasive surgical procedure for the treatment of nearly all femoral fracture patterns. Sixty-six fractures, 5 cases of osteolysis or pathologic fractures, 2 limb shortenings and 1 lengthening (monorail technique) and 3 cases of pseudarthrosis were stabilised with the UFN from July 1994 to December 1996. The fractures were analysed according to the AO classification. We found 31 polytrauma patients with an mean ISS of 21.8 and a mean PTS of 25.4. Most of the multiply injured patients (n = 26) were stabilised with the UFN primarily. Follow-up of 44 patients ranged from 4 to 18 months postoperatively. According to our clinical and radiological score the results were excellent in 34 % of cases, good in 36.3 %, poor in 20.4 % and bad in 9 %. Average fracture healing time was about 9.8 weeks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001040050260
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  • 5
    Electronic Resource
    Electronic Resource
    Experimental study of bone-implant contact with a parabolic acetabular component (Hofer-Imhof) (2000)
    Springer
    Archives of orthopaedic and trauma surgery 120 (2000), S. 160-165 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Incomplete bone contact with threaded acetabular components is usually attributable to the tapered thread design and sclerotic bone, and might be the reason for early loosening. The self-tapping flat threads of the Hofer-Imhof cup allow accurate insertion without incarceration, even in sclerotic bone. To demonstrate the effectiveness of this threaded cup design based on digitized measurements of bone contact area, six Hofer-Imhof cups were implanted into three human cadavers. The bone contact area at the threads was digitally analyzed on cadaver-explanted cups cut into horizontal and coronal sections. In cups fixed with ideal form fit, bone contact was 31.6% (range 8–55%) at the threads and 28.5% (range 0–49%) between the threads on average. In cups with incomplete bone contact secondary to insufficient reaming, the bone contact area averaged 27.4% (range 10–44%) at the threads. In sclerotic bone, the highest bone contact at the threads was 69%. The threads were the first part of the cup to achieve primary bone contact. Factors contributing to poor contact were incomplete reaming, sections which passed through the incisura of the acetabulum, and incomplete contact with the medial aspect of the acetabulum. The aim was to achieve complete bone contact. Because of the higher contact areas observed in sclerotic bone, some sclerotic bone should remain after reaming.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004020050035
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  • 6
    Electronic Resource
    Electronic Resource
    Properties of pseudo-holomorphic curves in symplectisations II: Embedding controls and algebraic invariants (1995)
    Springer
    Geometric and functional analysis 5 (1995), S. 270-328 
    Details
    ISSN: 1420-8970
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01895669
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  • 7
    Electronic Resource
    Electronic Resource
    A non-receptor-type protein phosphotyrosine phosphatase is enriched in secretory vesicles of glucagon – and pancreatic polypeptide – secreting cells of the endocrine pancreas (1999)
    Springer
    Histochemistry and cell biology 111 (1999), S. 135-142 
    Details
    ISSN: 1432-119X
    Keywords: Key words Tyrosine phosphatase ; Glucagon ; Pancreatic polypeptide ; Somatostatin ; Endocrine secretion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Abstract  The secretory vesicles of some cells of the islets of Langerhans of the pancreas contain high amounts of immunoreactive tyrosine phosphatase of the PTP1B/TCPTP subfamily. The cells are located in the peripheral parts of the islets and were identified as glucagon- and pancreatic polypeptide-forming cells. The tyrosine phosphatase is also enriched in some of the somatostatin-producing cells but is not elevated either in insulin-producing B-cells or in the exocrine pancreas. Virtually the same patterns were found in pancretic tissues of rats, guinea pigs, pigs, and mice. High levels of detergent-soluble tyrosine phosphatase were measured in the particular fraction of pancreatic islets with a substrate preferred by PTP1B/TCPTP-type protein tyrosine phosphatases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004180050343
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  • 8
    Electronic Resource
    Electronic Resource
    Blood vessels surrounded by connective tissue (perivascular space) in the brain of Lepidosteus (Ganoidei) and some teleost fishes (1974)
    Springer
    Cell & tissue research 153 (1974), S. 435-448 
    Details
    ISSN: 1432-0878
    Keywords: Brain vessels ; Perivascular space ; Connective tissue ; Blood-brain-barrier ; Lepidosteus (Ganoidei) ; Teleosts
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Blood vessels surrounded by unusually wide perivascular spaces rich in connective tissue were observed in the brain of Lepidosteus (Ganoidei). Connective-tissue sheaths measuring up to 13 μm in width enclose arterioles and venules (40–70 μm in diameter), and even capillaries may be encompassed by a cuff formed by collagen fibers. Blood vessels with wide perivascular spaces are mainly located in the subependymal layer of the lateral ventricles, near the mesencephalic aqueduct and in the folded basal lining of the fourth ventricle. At the light-microscopic level these vessels do not show any distinct contact with nervous elements (axons). Some other brain regions of Lepidosteus, e.g. mesencephalic tectum, are supplied by a conventional type of capillaries, free of connective-tissue linings. For comparative reasons, brains of several selachian and teleostean species were examined with comparable histological methods. Distinct perivascular spaces were found in the pike, in the trout and in the eel. They are considerably richer in connective tissue than the occasionally observed narrow perivascular spaces in the shark. The significance of the abundant perivascular connective tissue in the brain of Lepidosteus is open to discussion; structural and functional problems of the brain-blood-barrier have been reviewed in this context. The brain of Lepidosteus appears to be a very suitable model for studies of blood supply, vascular ultrastructure and blood-brain-barrier functions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00231539
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  • 9
    Electronic Resource
    Electronic Resource
    Applications of symplectic homology II stability of the action spectrum (1996)
    Springer
    Mathematische Zeitschrift 223 (1996), S. 27-45 
    Details
    ISSN: 0025-5874
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00004267
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  • 10
    Electronic Resource
    Electronic Resource
    Postoperative halswirbelsäule und beurteilung des rückenmarks mittels magnetresonanztomographie (1995)
    Springer
    Langenbeck's archives of surgery 380 (1995), S. 203-206 
    Details
    ISSN: 1435-2451
    Keywords: Magnetic resonance imaging ; Cervical spine ; Titanium implant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die Vorstellung von 10 Patienten, von denen sich 8 Rückenmarkschädigungen und 2 radikuläre Beeinträchtigungen im Rahmen von Dislokationsverletzungen der HWS zuzogen und die nach Stabilisierungsoperationen im Zeitraum von 2 Tagen bis 8 Monaten mittels MRT abgekldrt werden, verfolgt das Ziel, die Einsatz-und Aussagembglichkeiten dieser nicht-invasiven Methode darzustellen. Bei 2 Patienten mit schwerem Schädelhirntrauma konnte die Ursache für die Querschnittsläsion eindeutig einer Rückenmarkschädigung zugeordnet werden. Ebenso korrelierten schwere Binnenschäden des Rückenmarks, wie intramyeläre Hämatome oder Transsektionen, mit kompletten Querschnittsläsionen. Alleinige Rückenmarködeme traten mit einer inkompletten Querschnittsläsion auf. Die Beurteilung des Ruckenmarks nach postoperativer neurologischer Verschlechterung ermöglicht den Ausschluß einer Rückenmarkkompression als Ursache. Die MRT eignet sich auch zur lebenslangen Beurteilung von Rückenmark- und HWS-Veränderungen. Somit kann das Rückenmark mit der postoperativen MRT in Problemfällen und zur Prognoseerstellung herangezogen werden.
    Notes: Abstract We present the cases of ten patients who underwent postoperative magnetic resonance assessment after dislocation injuries of the cervical spine and treatment with anterior interbody fusion and titanium implants. Eight patients had spinal cord injuries and two had nerve root disorders. In two patients who had intracranial haematomas and dislocation fractures of the cervical spine, MRI proved useful for identification of parenchymal spinal cord injuries as the reason for transverse lesions. Severe MR findings of the parenchymal spinal cord injuries (haematoma or transection) correlated with complete transverse lesions (4 patients) and oedema of the spinal cord, with incomplete transverse lesions (3 patients). MR enables us to examine the spinal cord after operations to ensure that correct spinal cord decompression has been achieved (3 patients). MRI is useful for detecting disc protrusion or chronic spinal stenosis in patients with titanium implants. All in all, MRI is an important modality in the evaluation of the posttraumatic cervical spine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00207908
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