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  • 2000-2004  (125)
  • 1995-1999  (312)
  • 1935-1939  (16)
  • 1915-1919  (9)
  • 1860-1869  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Anaesthesia 52 (1997), S. 0 
    ISSN: 1365-2044
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Thirteen patients were monitored for nocturnal body position (supine vs. side) and arterial oxygen saturation pre-operatively and on the second postoperative night after major abdominal surgery. The number of positional changes were significantly decreased after operation (p 〈 0.05) with a trend towards more time spent in the supine position (p = 0.1). Individual mean arterial oxygen saturation decreased postoperatively (p 〈 0.05) but without a difference between the supine and side positions (p = 0.9). Pre-operatively, episodic desaturations were significantly more frequent in the supine position than on the side (p 〈 0.05) but not postoperatively. Pain was the most frequent reason for decreased nocturnal movements.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-7217
    Keywords: estrogens ; antiestrogens ; antiprogestins ; progestins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The pure antiestrogen ICI 182,780 has been shown to have antiprogestin activity in reporter gene constructs. Cell lines, naturally devoid of progesterone receptors (PR) were transfected with either the A or B forms of the human PR and a luciferase construct driven by a progesterone-response element (PRE). Because this system is an artificial one, our purpose was to determine whether these observations could be made in a human breast cancer cell line, naturally containing PR. We further evaluated the dose-response of ICI 182,780 and RU-486 (mifepristone) on PR and estrogen receptors (ER) in the presence of either progesterone, norgestrel or estradiol. These effects were measured using immunoassays for prostate-specific antigen (PSA) and human glandular kallikrein (hK2) and pS2. We found that ICI 182,780 blocked progesterone-stimulated PSA and hK2 production 100% at 10−5 M, which decreased significantly by 10−6 M. This inhibition did not occur when norgestrel was the progestin used. RU-486 showed 100% blockade for both progestins at all concentrations used. We concluded that the antiprogestin activity of ICI 182,780 exists for progesterone only. This weak antiprogestin activity may be unlikely to have significant clinical implications.
    Type of Medium: Electronic Resource
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  • 3
  • 4
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 89 (2001), S. 3033-3040 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The results of room-temperature wet etching of GaAs using synchrotron-radiation x rays are described. Under x-ray illumination, etching occurs on the n-GaAs surface in contact with an acid or base solution or even deionized water. The etching process is studied as functions of the electrolytes, their concentration, semiconductor doping level, and x-ray intensity and energy. The etching mechanism is determined to be primarily electrochemical in nature, but the x-ray radiation chemistry plays a role in the etching. Smoothly etched surfaces are achievable with a root-mean-square surface roughness of 0.7–2.0 nm. We also found that the etching rate increases substantially with the ratio of the sample size to the x-ray exposure size. This is accounted for by the rate-limiting effect on the charge transfer across the semiconductor-electrolyte junction. The chemistry of etched surfaces is studied using x-ray photoelectron spectroscopy and compared to that of as-received surfaces. © 2001 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 88 (2000), S. 2177-2178 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: In a recent article, Nagayama and Mori [J. Appl. Phys. 84, 6592 (1998)] arrived at several conclusions concerning the thermodynamic nature of shock loaded plexiglass in the low stress range. Their departure point is the kink in the shock velocity-particle velocity curve for this material from which they obtain kinks in the temperature versus shock stress and Gruneisen parameter versus compression curves. These results are in sharp contrast with our conclusions concerning these entities which were published in the early 80's. Our experimental work relied on measuring the temperature of the shock loaded plexiglass using very thin copper thermistors embedded in the specimens. This technique and our main results are reviewed here. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 86 (1999), S. 4107-4117 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We present a detailed study of the recently discovered modulation at frequencies of hundreds of MHz of an electron beam produced by a plasma cathode. The plasma cathode consists of a ferroelectric disk sample [BaTiO3 or Pb(Zr, Ti)O3] that is placed in a cylindrical metal box having an output window covered by a grid. The plasma is prepared by an incomplete discharge that was ignited by a few kV driving pulse applied across the ferroelectric disk. It was shown that the current modulation appears only when the driving pulse is applied to the front gridded electrode of the ferroelectric sample and the solid rear electrode is grounded. The modulation spectrum is quite narrow (≤3%), with harmonics at frequencies up to a few GHz. The basic frequency of modulation was found to be dependent on the length of the feed cable to the sample. Investigation of the plasma and the beam modulation properties and their dependence on the experimental parameters is presented. The results indicate the formation of a plasma at the vicinity of the front electrode of the ferroelectric sample during the modulation. The results are discussed within the frame of electrons oscillating in the potential well created by the positively charged plasma having feedback coupling with the input cable. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 3 (1996), S. 1202-1211 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effect of negative ions on the collisionless electrostatic ion cyclotron instability (EICI) is investigated analytically and numerically. The singly ionized negative ion species has mass greater than or equal to the mass of the singly ionized positive ion species. Standard linear Vlasov theory is used to estimate the critical electron drift velocity. It is shown that the critical drifts for the excitation of both the light and heavy ion EIC modes decrease as the relative density of negative ions increases. Our results are compared with available negative ion plasma experiments concerning the EICI, and possible applications to experiments in the ionosphere are briefly discussed. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 5 (1998), S. 3786-3788 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The effect of longitudinal boundaries on electrostatic instabilities driven by an ion beam in a dusty plasma is considered. In analogy with instabilities in electron-ion plasma diodes, in this case both the low-frequency ion-space-charge waves and ion-dust waves can be unstable. The growth rates and ion current thresholds are estimated. The present investigation should help to design a large scale dusty plasma device to study these low-frequency analogs of instabilities in bounded beam-plasma systems. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Physics of Plasmas 3 (1996), S. 644-649 
    ISSN: 1089-7674
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Low frequency drift instabilities are investigated in a dusty magnetized plasma with negatively charged grains in which locally there is an electron density gradient which is opposite in sign to a dust density gradient. Frequencies less than the ion gyrofrequency but much larger than the dust gyrofrequency are considered. Two different equilibria are considered that are characterized by ρd≥Lnd, where ρd is the dust gyroradius and Lnd is the dust density scale length. Instabilities analogous to the universal instability and to the lower-hybrid-drift instability (with the lower-hybrid frequency in this case associated with the dust) are investigated. Possible applications to dusty space plasmas such as the spoke regions of Saturn's B-ring are discussed. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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