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  • 2000-2004  (8)
  • 1985-1989  (12)
  • 1975-1979  (14)
  • 1965-1969  (1)
  • 1960-1964  (1)
  • 1955-1959  (2)
  • 11
    Electronic Resource
    Electronic Resource
    Involvement of N-Methyl-D-Aspartic Acid Receptor Activation in Oxytocin and Vasopressin Release After Osmotic Stimuli in Rats (2001)
    Oxford, UK : Blackwell Science, Ltd
    Journal of neuroendocrinology 13 (2001), S. 0 
    Details
    ISSN: 1365-2826
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The present study aimed to examine roles of N-methyl-D-aspartic acid (NMDA) receptors in oxytocin and vasopressin release after osmotic stimuli. A noncompetitive NMDA receptor antagonist, MK-801 (0.2 mg/kg body weight, i.p.), significantly decreased plasma concentrations of oxytocin and vasopressin after hypertonic saline injection (0.3 or 0.6 M NaCl, i.p., 20 ml/kg). By contrast, oxytocin release induced by injection of cholecystokinin octapeptide (20 µg/kg, i.p.) was not significantly changed by MK-801. Hypertonic saline injection increased the number of cells expressing Fos in the supraoptic nucleus and in the regions anterior and ventral to the third ventricle (AV3V) regions [the organum vasculosum of the lamina terminalis (OVLT) and median preoptic nucleus]. MK-801 decreased the number of cells expressing protein in these areas after hypertonic saline injection. A microdialysis method showed that a hypertonic saline injection (0.6 M NaCl, 20 ml/kg, i.p.) facilitated glutamic acid release in and near the OVLT. The results support the view that NMDA receptor in the AV3V region modulates in a facilitative fashion the AV3V inputs to the supraoptic neurosecretory neurones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2826.2001.00607.x
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  • 12
    Electronic Resource
    Electronic Resource
    LIFE PREDICTION OF 316 STAINLESS STEEL UNDER CREEP-FATIGUE LOADING (1987)
    Oxford, UK : Blackwell Publishing Ltd
    Fatigue & fracture of engineering materials & structures 9 (1987), S. 0 
    Details
    ISSN: 1460-2695
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Life prediction for creep-fatigue loading conditions should be related to creep damage mechanisms. In order to examine the effect of the creep damage mode on rupture life under creep-fatigue loading, a “combined creep-fatigue loading test” was carried out on 316 stainless steel. In this method, creep loading and fatigue loading are repeated alternately. The fracture criteria under combined loading closely depend on the creep fracture modes of the static creep test. A new life prediction method which uses this new fracture criterion is proposed. The criteria are changed when the creep damage mode varies. In order to verify the adequacy of this method, fatigue tests with a tensile strain-hold wave form were carried out. It is clear that rupture life in such fatigue tests is dependent on the chosen fracture criteria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1460-2695.1987.tb00467.x
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  • 13
    Electronic Resource
    Electronic Resource
    The roles of prostaglandin E receptor subtypes in the cytoprotective action of prostaglandin E2 in rat stomach (2000)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 14 (2000), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Aim: To investigate the EP receptor subtype involved in the gastroprotective action of prostaglandin (PG) E2 using various EP receptor agonists in rats, and using knockout mice lacking EP1 or EP3 receptors. Methods: Male SD rats and C57BL/6 mice were used after an 18-h fast. Gastric lesions were induced by oral administration of HCl/ethanol (150 m m HCl in 60% ethanol). Rats were given various EP agonists i.v. 10 min before HCl/ethanol: PGE2, sulprostone (EP1/EP3 agonist), butaprost (EP2 agonist), 17-phenyl-ω-trinorPGE2 (17-phenylPGE2: EP1 agonist), ONO-NT012 (EP3 agonist) and 11-deoxyPGE1 (EP3/EP4 agonist). In a separate study, the effect of PGE2 on HCl/ethanol lesions was examined in EP1- and EP3-receptor knockout mice. Results: Gastric lesions induced by HCl/ethanol were dose dependently prevented by PGE2; this effect was mimicked by sulprostone and 17-phenylPGE2 and was significantly antagonized by ONO-AE-829, an EP1 antagonist. Neither butaprost, ONO-NT012 nor 11-deoxyPGE1 exhibited any protective activity against HCl/ethanol-induced gastric lesions. PGE2 caused an inhibition of gastric motility as well as an increase of mucosal blood flow and mucus secretion, the effects being mimicked by prostanoids activating EP1 receptors, EP2/EP3/EP4 receptors and EP4 receptors, respectively. On the other hand, although HCl/ethanol caused similar damage in both wild-type mice and knockout mice lacking EP1 or EP3 receptors, the cytoprotective action of PGE2 observed in wild-type and EP3-receptor knockout mice totally disappeared in mice lacking EP1 receptors. Conclusion: The gastric cytoprotective action of PGE2 is mediated by activation of EP1 receptors. This effect may be functionally associated with inhibition of gastric motility but not with increased mucosal blood flow or mucus secretion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2000.014s1116.x
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  • 14
    Electronic Resource
    Electronic Resource
    Reflection electron microscopy (1987)
    Copenhagen : International Union of Crystallography (IUCr)
    Applied crystallography online 20 (1987), S. 147-160 
    Details
    ISSN: 1600-5767
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Geosciences , Physics
    Notes: Reflection electron microscopy (REM) in ultra-high vacuum (UHV) conditions is reviewed. UHV-REM can characterize surface structures of monolayer levels such as steps, domains of reconstructed surface structures and their boundaries and these capabilities are used to observe surface dynamic processes such as phase transitions of reconstructed surface structures and adsorbate structures and adsorption processes, oxidations, sublimations and ion-sputtering and annealing. The method is compared with other surface-imaging techniques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0021889887086916
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  • 15
    Electronic Resource
    Electronic Resource
    Electron microscopy study of ordering of potassium ions in cubic KSbO3 (1978)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 34 (1978), S. 625-634 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Ordered and disordered states of potassium ions in (111) tunnels in the structure of cubic KSbO3 have been studied by high-resolution electron microscopy. N-beam calculations for the images of both the ordered and disordered states reproduce well the observed images. The disordered state changes into the ordered state under electron irradiation during the observations. Electron diffraction from the specimens and optical diffraction from the images show diffuse spots due to small domains of the long-range-ordered state, but no other diffuse scattering due to short-range order has been observed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739478001291
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  • 16
    Electronic Resource
    Electronic Resource
    Electron-microscope study of the crystal structures of mixed oxides in the systems Rb2O–Ta2O5, Rb2O–Nb2O5 and K2O–Ta2O5 with composition ratios near 1:3. I. Stacking characteristics of MO6 layers (1978)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 34 (1978), S. 765-773 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The crystal structures of phases, previously designated as 11L, 9L and 16L, which were commonly found in the title systems are suggested from their high-resolution two-dimensional electron-microscope images. Two types of blocks are found which are composed of five and six layers of pentavalent-metal oxide octahedra and are closely related to the pyrochlore structure. The 11L structure is of rhombohedral {\tt ABCABC} stacking of the former type of block, and the 9L structure is of hexagonal {\tt B}_{0}{\tt A}_{0}^{\prime}{\tt B}_{0}{\tt A}_{0}^{\prime} stacking of the latter type of block. The 16L structure is found to be an alternate stacking of the two types of blocks. The method of stacking of the blocks is the same for the three structures and is found to be favorable from the point of view of local charge balance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0567739478001588
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  • 17
    Electronic Resource
    Electronic Resource
    Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs (2002)
    [s.l.] : Macmillian Magazines Ltd.
    Nature 420 (2002), S. 563-573 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the mouse, and to ensure that each is represented in a physical collection of clones. Here we report the ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/nature01266
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  • 18
    Electronic Resource
    Electronic Resource
    Separation of Flavins by Ion-Exchange Resins (1955)
    [s.l.] : Nature Publishing Group
    Nature 175 (1955), S. 555-556 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] Using an anion-exchange resin, Cohn et ol. have reported the separation of adenosine and adenosine mono-, di- and tri-phosphates4, and that of choline and its ester6. For the separation of flavin compounds by ion exchange, several ion exchangers were examined, and the anion-exchange resin, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/175555a0
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  • 19
    Electronic Resource
    Electronic Resource
    Electron microscope analyses of domains and discommensurations in ferroelectric Rb2ZnCl4. Erratum (1989)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 45 (1989), S. 146-146 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: The following corrections should be made in Tsuda, Yamamoto & Yagi [Acta Cryst. (1988). A44, 864-870]. (1) 'only two kinds of domain boundaries' in the Abstract should be changed to 'two kinds of image contrast of domain boundaries'. (2) The expressions for h2, h4, h6 in § 4.1 should be replaced by h2: -x -y -z + h4: -x -y -z (inversion) h6: -x -y -z + (3) "two kinds of DC's showing different contrast' in the second paragraph in § 4.1 should be changed to 'two kinds of DC contrast'.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108767388012395
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  • 20
    Electronic Resource
    Electronic Resource
    Electron microscope analyses of domains and discommensurations in ferroelectric Rb2ZnCl4 (1988)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 44 (1988), S. 864-870 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: Image contrast of domains and discommensurations in ferroelectric Rb2ZnCl4 is studied. Six domains of the two orientation variants and three translation variants in the ferroelectric phase are observed. However, only two kinds of domain boundaries, which are the discommensurations in the incommensurate phase of Rb2ZnCl4, are observed. These observations agree with group-theoretical considerations of the phase transition from the normal phase to the commensurate phase of Rb2ZnCl4.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108767388004945
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