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  • 2000-2004  (3)
  • 1980-1984  (10)
  • 1975-1979  (5)
  • 1930-1934  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The role of histidine in human epidermis (1977)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 97 (1977), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Incorporation of radioactively-labelled histidine into half-thickness skin and into the major protein fraction extracted from epidermis by urea (protein Fraction A) has been measured and compared with the amount of labelled urocanic acid appearing in the same specimen.After a short lag period, incorporation into half-thickness skin and into protein Fraction A was foxmd to be linear up to 23 h of the study.Histidine appeared to be initially preferentially deaminated to urocanic acid. The somewhat erratic presence of urocanic acid at later periods is attributed to its high instability and solubility.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1977.tb14246.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Periodontal diseases and impaired neutrophil function (1982)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 17 (1982), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1982.tb02036.x
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Biological effects of a purified lipopolysaccharide from Bacteroides gingivalis (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of periodontal research 18 (1983), S. 0 
    Details
    ISSN: 1600-0765
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Lipopolysaccharide (LPS) has been purified from Bacteroides gingivalis. The purity of this LPS is evidenced on ultracentrifugation, immunoelectrophoresis, and chemical analyses. On comparison with LPS from aerobic enteric organisms, LPS from Bacteroides gingivalis exhibits minimal potency when tested for pyrogenicity in rabbits and mitogenicity in mouse spleen cells. On the other hand, purified LPS from Bacteroides gingivalis exhibits high potency in its ability to stimulate 45Ca release from prelabeled fetal rat bones and to inhibit Ca influx into osteoclast-like cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0765.1983.tb00333.x
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Precursor keratin protein from human epidermis (1978)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 98 (1978), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Prekeratin has been isolated from human epidermis using the method of Matoltsy for bovine nose epidermis. Analysis by sedimentation equilibrium indicates that human prekeratin is heterogeneous in solution. The molecular weight range is from about 200 × 103 to at least 2 × 106. Polyacrylamide gel electrophoresis shows three polypeptide chains of molecular weights 65,000, 60,000 and 58,000. A lower than average ratio of polar/apolar amino acid residues suggests that hydrophobic interactions are important for stability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1978.tb01618.x
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    A conserved DNA sequence in homoeotic genes of the Drosophila Antennapedia and bithorax complexes (1984)
    [s.l.] : Nature Publishing Group
    Nature 308 (1984), S. 428-433 
    Details
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] A repetitive DNA sequence has been identified in the Drosophila melanogaster genome that appears to be localized specifically within genes of the bithorax and Antennapedia complexes that are required for correct segmental development. Initially identified in cloned copies of the genes Antennapedia, ...
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1038/308428a0
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Protein-predominant meals inhibit the development of gastric tachyarrhythmia, nausea and the symptoms of motion sickness (2004)
    Oxford, UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 19 (2004), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background : Meal ingestion has been suggested to reduce susceptibility to the development of gastric tachyarrhythmia, the abnormal activity of the stomach that frequently accompanies nausea.Aim : To determine the types of meal that are most effective in preventing the development of gastric tachyarrhythmia, nausea and the symptoms of motion sickness provoked by a rotating optokinetic drum.Method : Participants received a carbohydrate beverage, a protein-predominant beverage or nothing immediately before exposure to the rotating drum. Subjective symptoms of motion sickness and electrogastrograms were collected during a 6-min baseline period and a subsequent 16-min drum rotation period.Results : Subjective symptoms of motion sickness scores were significantly more severe during the no-meal condition than during either the protein or carbohydrate condition. Central, peripheral and, to some extent, gastrointestinal symptoms were more severe during the carbohydrate condition than during the protein condition. Gastric tachyarrhythmia increased significantly less from baseline to drum rotation during both the protein and carbohydrate conditions than during the no-meal condition.Conclusions : Liquid protein-predominant meals were most effective in suppressing both the development of gastric tachyarrhythmia and the entire spectrum of motion sickness symptoms, including nausea.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2036.2004.01885.x
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Fibrous proteins of normal and abnormal human epidermis (1979)
    Oxford, UK : Blackwell Publishing Ltd
    British journal of dermatology 100 (1979), S. 0 
    Details
    ISSN: 1365-2133
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Keratin proteins of human epidermis have been isolated from normal and abnormal tissues. The normal proteins whether removed from living layers (prekeratin) or from the stratum corneum (keratin) are shown to consist of three chains, molecular weights 65,000 (A), 60,000 (B) and 52,000 (C). When compared with the epidermal proteins isolated from abnormal tissues, differences can be detected in the electrophoretic pattern of the subunits. In general, relative amounts of the individual chains are altered and in specific cases one or two of the polypeptides found normally are missing. All the α-fibrous proteins extracted are found to be very similar in amino acid composition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2133.1979.tb01640.x
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  • 8
    Electronic Resource
    Electronic Resource
    A method for the systematic comparison of the three-dimensional structures of proteins and some results (1984)
    [S.l.] : International Union of Crystallography (IUCr)
    Acta crystallographica 40 (1984), S. 600-610 
    Details
    ISSN: 1600-5724
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Notes: A new rapid method of comparing three-dimensional protein structures using the sequence of dihedral angles is described. Systematic screening of protein structures by this method followed by detailed analysis reveals in particular that the calcium-binding protein carp parvalbumin is similar to cytochrome C2 from Rhodospirillum rubrum, cytochrome C is similar to hen lysozyme, carboxypeptidase A is similar to phage lysozyme. These results are completely unexpected and show interesting correlation with the recently determined intron-exon pattern in the genes coding for some of them.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108767384001239
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  • 9
    Electronic Resource
    Electronic Resource
    Antibody-based diagnostic for ‘refractory’ periodontitis (2002)
    Oxford, UK : Munksgaard International Publishers
    Journal of clinical periodontology 29 (2002), S. 0 
    Details
    ISSN: 1600-051X
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective: About 10–15% of US adults are ‘refractory’ to therapy for chronic periodontitis. Recently, studies suggest that these patients have elevated lysine decarboxylase activity in the sulcular microbiota. The aim of this study was to determine whether an elevated IgG antibody response to lysine decarboxylase, alone or with antibody to other bacterial antigens and baseline clinical measurements, would predict ‘refractory’ patients with high accuracy.Methods: Chronic periodontitis patients were treated using scaling and root planing (SRP) followed by maintenance SRP and 3-monthly re-examinations. If there was a loss of mean full mouth attachment or more than three sites appeared with 〉 2.5 mm new loss within a year, the subjects were re-treated (modified Widman flap surgery and systemically administered tetracycline). If attachment loss as above recurred, the subjects were ‘refractory’. Baseline clinical measurements and specific antibody responses were used in a logistic regression model to predict ‘refractory’ subjects.Results: Antibody to a peptide portion of lysine decarboxylase (HKL-Ab) and baseline bleeding on probing (BOP) prevalence measurements predicted attachment loss 3 months after initial therapy [pIAL = loss (0) or gain (1)]. IgG antibody contents to a purified antigen from Actinomyces spp. (A-Ab) and streptococcal d-alanyl glycerol lipoteichoic acid (S-Ab) were related in ‘refractory’ patients (R2 = 0.37, p 〈 0.01). From the regression equation, the relationship between the antibodies was defined as linear (pLA/S-Ab = 0) or non-linear pLA/S-Ab = 1). Using pLA/S-Ab, pIAL and age, a logistic regression equation was derived from 48 of the patients. Of 59 subjects, 37 had 2–4 mm attachment loss and were assigned as ‘refractory’ or successfully treated with 86% accuracy.Conclusion: HKL-Ab facilitated an accurate prediction of therapeutic outcome in subjects with moderate periodontitis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1034/j.1600-051X.2002.291009.x
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  • 10
    Electronic Resource
    Electronic Resource
    Some sensory and motor factors influencing the control and appreciation of eye and limb position (1979)
    Springer
    Experimental brain research 36 (1979), S. 275-283 
    Details
    ISSN: 1432-1106
    Keywords: Spatial orientation ; Visual direction ; Motor control ; Tonic vibration reflex ; Myesthetic illusions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Some aspects of the manner in which the central nervous system uses sensory information for the guidance of eye and arm movements were investigated. When subjects experience apparent motion of their restrained forearm, induced by vibration of their biceps muscle in the dark, they are able to pursue with their eyes at least part of this “motion” and to point with their nonvibrated limb to the apparent location of the vibrated arm. The presence of a small target light on the vibrated hand limits the extent of illusory change in limb position and results in illusory motion of the target light in the same direction as the arm motion. When asked to indicate the spatial position of the light or hand, subjects still point with their nonvibrated arm to the apparent locations. Although visual pursuit of the illusory motion of the forearm can still be elicited in the presence of the target light on the hand, the subjects' eyes remain steadily fixating the stationary target light when they are instructed to track its illusory motion. These findings demonstrate that sensory and motor factors affecting the perception of visual direction and the guidance of arm and eye movements can be differentially employed at several levels of central nervous control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238911
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