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  • 1
    Electronic Resource
    Electronic Resource
    Adsorption geometries of CO on Cu (211) (1999)
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 10522-10525 
    Details
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The adsorption of CO on Cu (211), serving as model system for the adsorption of CO in stepped surfaces, has been investigated using electron energy loss spectroscopy (EELS). At a surface temperature of 110 K, CO adsorbs nondissociatively and is drawn exclusively to descending step sites in this system. On-top and bridge sites are sequentially populated with the CO axis being perpendicular to the surface. In addition, at low coverage, a molecular state is observed, for which the CO axis is strongly inclined. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.478983
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  • 2
    Electronic Resource
    Electronic Resource
    Confocal theta microscope with three objective lenses (1994)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 65 (1994), S. 3367-3372 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A microscope using three water immersion objective lenses which realizes confocal, 4Pi-confocal and various confocal theta microscopies in fluorescence, transmission, scattered, and reflection mode is described. An argon-ion laser is the primary light source. A pulsed titanium-sapphire laser allows two-photon absorption fluorescence microscopy. The instrument has a predicted resolution of 100 nm along the illumination axis and a three-dimensional resolution of 5×106 nm3 for lenses each with a numerical aperture of 0.75. This is an improvement of an order of magnitude over a confocal fluorescence microscope using the same lens. Applications of the microscope range from observation of a sample at three different angles, to confocal theta fluorescence microscopy with multiphoton absorption. Since mounting and immersion media are identical, aberrations become negligible. The large working distance of 2 mm makes the instrument ideal for the observation of biological samples of up to 1.5 mm in diameter such as drosophila embryos.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1144574
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  • 3
    Electronic Resource
    Electronic Resource
    A confocal fiber-coupled single-lens theta microscope (1998)
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 69 (1998), S. 2956-2963 
    Details
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: A confocal theta microscope using a single water-immersion objective lens is described. The system is based on the Zeiss Axioplan universal microscope, such that the illumination light is coupled into, and the detected light out of, the microscope optics via optical fibers attached to the reflector slider of the microscope. Conventional wide-field, laser-scanning confocal, confocal theta, and 4Pi-confocal theta microscopy modes are available with the system. As the design can be easily adapted to other microscopes, objective lenses, and wavelengths, it allows confocal theta techniques to be implemented in many standard systems. The design constraints and specifications for the microscope are given, as well as a demonstration of its performance. © 1998 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.1149040
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  • 4
    Electronic Resource
    Electronic Resource
    High-resolution axial and lateral position sensing using two-photon excitation of fluorophores by a continuous-wave Nd:YAG laser (1996)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 69 (1996), S. 446-448 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The change in position of fluorescent beads captured inside the focal volume of optical tweezers is monitored using fluorescence emission induced by two-photon absorption of a continuous-wave Nd:YAG laser (λ=1064 nm). The displacement of a bead due to interactions with its environment leads to a fluorescence intensity variation that is used to design a novel spatial sensor. We determine changes in the axial position of a CY3-labeled latex bead with a diameter of 1.03 μm to a precision better than 10 nm. At an intensity of 600 mW/ μm2 the two-photon bleaching rate is lower than 50% per 2000 s. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.118134
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  • 5
    Electronic Resource
    Electronic Resource
    PRELIMINARY, DERMATOLOGIC EIRST STEP CRITERIA FOR LUPUS ERYTHEMATOSUS AND SECOND STEP CRITERIA FOR SYSTEMIC LUPUS ERYTHEMATOSUS (1993)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 32 (1993), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background. Comparisons of cases of systemic lupus erythematosus (SLE) with cases of rheumatoid arthritis and other rheumatologic disorders affords the basis of the 1982 revised criteria of the American Rheumatism Association (ARA) for classifying SLE cases. We address three questions: Do comparisons of LE cases with non-LE cases that have suggestive skin lesions yield criteria for use in dermatology clinics for primary classification of cases with photo distributions of skin lesions? Do comparisons of SLE with cutaneous LE cases yield the same or similar criteria to the revised ARA criteria for SLE? How should subacute cutaneous LE cases be evaluated for signs of significant systemic involvement? Methods. Discriminant analyses on 168 cases with skin lesions suggestive of LE were performed using data based on the ARA criteria for SLE and study factors for cutaneous LE suggested by the European Academy of Dermatology and Venereology. Results. These yielded two sets of criteria: (1) The 11 preliminary, dermatologic first step criteria (10 plus 1 for discoid lesions and histology) serve to classify cases as LE or non-LE. (2) The 11 preliminary, dermatologic second step criteria classify LE cases as cutaneous LE or systemic LE. Interestingly, 5 of 11 of these second step criteria differ from the 11 ARA criteria for systemic LE. These second step criteria afford a useful means of distinguishing between subacute cutaneous LE cases with or without significant systemic involvement. Conclusions. The study factors included in both the first and the second step criteria fall into three groups, notably clinical criteria, laboratory criteria, and “added study factors.” The latter factors distinguish between the groups compared (LE VS. non-LE and cutaneous vs. systemic LE) but not as well as the study factors included as “criteria.”
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1993.tb04019.x
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  • 6
    Electronic Resource
    Electronic Resource
    Classification of Skin Diseases by Noah Worcester (1991)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 30 (1991), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1991.tb03501.x
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  • 7
    Electronic Resource
    Electronic Resource
    CHRONIC ULCERATIVE STOMATITIS WITH STRATIFIED EPITHELIUM-SPECIEIC ANTINUCLEAR ANTIBODIES (1996)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 35 (1996), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background. In 1990 a new disease-associated antinuclear antibody was first recognized as a specific immunologic marker for a chronic form of ulcerative stomatitis (cus). Methods. Another case is reported herein and the subject of chronic ulcerative stomatitis with stratified epithelium-specific antinuclear antibodies (SES-ANA) is reviewed. Intraoral biopsies from this patient were submitted for microscopic examination and direct immunofluorescence. Indirect immunofluorescence studies were also performed. Serial SES-ANA titers were obtained with the patient on maintenance treatment with hydroxychloroquine. A skin biopsy of a recent lichenoid eruption was obtained and skin explants grown in the serum of this patient were studied in tissue culture with reference to SES-ANA binding and complement fixation. Results. Biopsy and serum studies confirmed a diagnosis of cus with SES-ANA in the patient reported. Skin biopsy showed lichen planus. The patient was treated with hydroxychloroquine with a favorable response. Serial SES-ANA titers did not parallel the disease activity. Among the substantive observations made from skin explants cultured in the serum of this patient was widespread fixation of C3 to the nuclei of basal cells. Conclusions. The case described herein extends the findings in cus to include lichenoid skin lesions. Records show that at least four of 11 cases of cus had skin lesions, whereas all had oral lesions. Stratified epithelium-specific antinuclear antibodies serve as the key marker of cus. Skin explants grown in the serum of this cus patient bind SES-ANA in tissue culture. Sections of explants fix complement. Titers of SES-ANA have been reported to parallel disease activity in one case, but not in the present case. Thus, there appears to be case-to-case variation. The treatment of choice for cus is hydroxychloroquine.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1996.tb03000.x
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  • 8
    Electronic Resource
    Electronic Resource
    PSEUDO-PYOSTOMATITIS VEGETANS (1995)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 34 (1995), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1995.tb01105.x
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  • 9
    Electronic Resource
    Electronic Resource
    “Zoological Classification” of Skin Diseases (1990)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 29 (1990), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1990.tb04854.x
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  • 10
    Electronic Resource
    Electronic Resource
    CLASSIFICATION OF SKIN DISEASES IN NINETEENTH CENTURY AMERICA (1993)
    Oxford, UK : Blackwell Publishing Ltd
    International journal of dermatology 32 (1993), S. 0 
    Details
    ISSN: 1365-4632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-4362.1993.tb01459.x
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