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  • 1
    ISSN: 1432-198X
    Keywords: Blood pressure ; Hypertension ; Ambulatory monitoring ; Reference values
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Ambulatory blood pressure monitoring (ABPM) was performed in 564 healthy schoolchildren during normal circadian activities. The data of two cohorts (155 boys and 139 girls aged 9–13 years and 184 boys and 168 girls with a body height between 120 and 155 cm) are presented. From the age of 9 to 13 years the mean 24-h systolic/diastolic blood pressure (SBP/DBP) increases from 107±9/ 66 ± 7 mmHg to 115 ± 13/68 ± 9 mmHg in boys and from 104 ± 5/64 ± 6 mmHg to 109 ± 8/65 ± 9 mmHg in girls. When related to body height the values rise from 105 ± 6/ 64 ± 6 mmHg at 120 cm to 113 ± 8/67 ± 7 mmHg at 155 cm in boys and from 100±7/65±7 mmHg to 112±9/ 66 ± 9 mmHg in girls. In comparison with the casual blood pressure data obtained from European studies, the presented ABPM values (daytime BP) are higher throughout, which may be explained by the increased activity during daytime with ABPM. There is a mean difference of 4.4 mmHg in boys and of 3.0 mmHg in girls for SBP and of 10.8 mmHg in boys and of 9.0 mmHg in girls for DBP when related to age. In relation to body height, there is a mean difference of 4.4 mmHg in boys and of 3.5 mmHg in girls for SBP and of 10.9 mmHg in boys and of 10.5 mmHg in girls for DBP. We conclude that standards derived from casual blood pressure measurements should not be used for the evaluation of ABPM data.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Pediatric cardiology 18 (1997), S. 146 -148 
    ISSN: 1432-1971
    Keywords: Key words: Dissection — Aneurysm ascending aorta — Coarctation — Atresia of the aortic isthmus — Childhood
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. A boy with atresia of the aortic isthmus suffered dissection of the aneurysmatic ascending aorta. It is assumed that he had coarctation as a newborn and survived the subsequently developed atresia because of extensive collateralization.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 53 (1966), S. 16-17 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 53 (1966), S. 381-381 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 54 (1967), S. 616-617 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 54 (1967), S. 114-114 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 56 (1969), S. 136-136 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1433-0393
    Keywords: SchlüsselwörterZervixkarzinom ; Strahlentherapie ; Kombinationstherapie ; 13cis-Retinsäure ; Interferon ; Key wordsCarcinoma of the cervix ; Radiotherapy ; Combination therapy ; 13-cis-retinoic acid ; Interferon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Although carcinoma screening is now widely available, cervical carcinoma is still the fourth most common tumour among women in the USA and in the western industrialized nations. There are about 14,000 new cases every year. In underdeveloped countries carcinoma of the cervix is widespread and often the most frequent tumour[18]. Besides primarily surgical treatment radiotherapy is the main curative treatment modality, the 5-year survival rates after therapy being around 90% for stage I disease and 7% for stage IV (FIGO Annual Report). It therefore seems desirable to look for therapeutic concepts, with the aim of improving the present results further by means of new combinations of irradiation with a systemic therapy.
    Notes: Zusammenfassung Trotz der weit verbreiteten Karzinomvorsorge stellt das Zervixkarzinom in den USA und den westlichen Industrienationen immer noch den vierthäufigsten Tumor bei Frauen dar. Die Anzahl von Neuerkrankungen beträgt ca. 14 000 neue Fälle pro Jahr. In unterentwickelten Ländern ist das Zervixkarzinom weit verbreitet und oft der häufigste Tumor[18]. Neben dem primär chirurgischen Vorgehen stellt die Strahlentherapie die wesentliche kurative Behandlungsmodalität dar, wobei die 5-Jahres-Überlebensraten nach Therapie bei 90% für das Stadium I und 7% für das Stadium IV liegen (FIGO Annual Report). Es erscheint daher sinnvoll, nach therapeutischen Konzeptionen zu suchen, um durch neue Kombinationen der Bestrahlung mit einer System-Therapie die gegenwärtigen Ergebnisse weiter zu verbessern.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Der Onkologe 5 (1999), S. 1103-1110 
    ISSN: 1433-0415
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Die Transplantat-Gegen-Wirt-Reaktion oder Graft-Versus-Host-Disease (GVHD) als Ausdruck der Immunreaktion zwischen Spenderlymphozyten und als „fremd” erkanntem Empfängerorganismus ist eine typische Komplikation z. B. nach allogener Knochenmarktransplantation [39]. Als verwandtes Krankheitsbild ist die seltene sogenannte Transfusions-assoziierte-Graft-Versus-Host-Erkrankung (TAGVHD) beschrieben. Voraussetzung für das Auftreten einer TAGVHD ist die Übertragung von teilungsfähigen allogenen Spender-Lymphozyten durch eine Transfusion in den Empfänger, welcher auf Grund seiner Immunitätslage nicht in der Lage ist, diese fremden Lymphozyten zu eliminieren. Die klinische Symptomatik ähnelt dem Bild einer GVHD mit den typischen Veränderungen an Haut, Darm und Leber [36, 37]. In Abhängigkeit von der Grunderkrankung und dem Allgemeinzustand ist die Letalität der TAGVHD trotz der modernen Möglichkeiten der Immunsuppression hoch und wird in der Literatur zwischen 75% und 90% angegeben [24]. Während lange Zeit vermutet wurde, daß das Krankheitsbild nur im Rahmen einer Hochdosistherapie nach peripherer Stammzelltransplantation oder auch nach allogener Knochenmarktransplantation (KMT) auftritt, ist heute bekannt, daß generell alle Blutempfänger mit mittelgradiger oder schwerer Immunsuppression sowie auch Empfänger von nur partiell HLA-indentischem Blutprodukten durch diese Komplikationen gefährdet sind. Hierzu zählen z. B. auch Organempfänger von Herz- oder Nierentransplantaten, Patienten mit malignen Lymphomen (auch nach konventioneller Chemotherapie), Frühgeborene oder Empfänger von Transfusionen unter Verwandten. Aufgrund der unbefriedigenden therapeutischen Möglichkeiten kommt der Prävention der TAGVHD in der Klinik eine besondere Bedeutung zu. Angestrebt wird vor der Transfusion eine möglichst komplette ▸Depletion teilungsfähiger Lymphozyten in der Transfusion, wofür in der Klinik die ex-vivo-Bestrahlung der Blutprodukte mit ionisierenden Strahlung Anwendung findet [16].
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Physics of the solid state 40 (1998), S. 1288-1289 
    ISSN: 1063-7834
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The shift in the nuclear magnetic resonance (NMR) line of 71Ga isotopes in GaAs crystals is investigated in the temperature range 160–360 K. It is observed that the position of the resonance line is temperature-independent. The value of the shift relative to an isolated nucleus is 440 and 420 ppm for the three samples investigated. The roles of various contributions to the NMR line shift are discussed.
    Type of Medium: Electronic Resource
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