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  • 1
    Electronic Resource
    Electronic Resource
    Triethyllead in the biological material in cases of acute tetraethyllead poisoning (1967)
    Springer
    Archives of toxicology 22 (1967), S. 278-282 
    Details
    ISSN: 1432-0738
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Triethyllead and the total lead were determind in the tissues in three acute fatal cases of tetraethyllead poisoning. In each case high concentrations of triethyllead were found (2.0–22.0 μg/g) being of the same range as the total lead content. The triethyllead content of the tissues showed a slightly decreasing trend with the length of the surviving period. High levels of the total lead were also found in blood (3.3–4.0 μg/ml), and urine (0.4–8.0 μg/ml), the highest values being observed after EDTA treatment. The triethyllead content in blood and urine was much lower.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00577718
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Effect of selenium on the organ distribution and binding of bismuth in rat tissues (1978)
    Springer
    Archives of toxicology 40 (1978), S. 131-141 
    Details
    ISSN: 1432-0738
    Keywords: Bismuth-organ distribution ; Bismuth-binding to kidney proteins ; Selenite-effect on distribution and bismuth binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Nach einmaliger und wiederholter subkutaner Verabreichung wurde Wismut zu mehr als 50% der „erreichbaren Menge” in den Nieren gefunden. Es war dort vorwiegend in der löslichen Frakion und in großem Umfang an einen Eiweißstoff vom Molekulargewicht 7000 gebunden. Bei wiederholter erabreichung von Wismut wurde auch dieser Eiweißstoff vermehrt gefunden. Die gleichzeitige Verabreichung von Selen erhöhte die „verfügbare Menge” von Wismut, wahrscheinlich wegen eingeschränkter Ausscheidung. Zugleich wurden Unterschiede in der Organverteilung von Wismut festgestellt. Der Anteil in den Nieren wirde geringer und derjenige in Leber und sonstigen. Organen größer. Der Eiweißkomplex mit dem Molekulargewicht 7000 verschwand gänzlich. Die durch Wismut stimulierte Synthese dieses Eiweißstoffes wirde aber nicht ganz verhindert.
    Notes: Abstract Subcutaneous administration of bismuth, both single and multiple, resulted in deposition of this metal mainly in the kidneys which contained over 50% of the ‘accessible pool’ of bismuth. In the kidneys bismuth was bound mainly by the soluble fraction in which it was complexed with a protein of molecular weight of about 7000. Multiple administration of bismuth increased the level of this protein. Selenite administration brought about an increase in the ‘accessible pool’ of bismuth, probably due to a drop in excretion, and also changes in the organ distribution of this metal. The retention in the kidneys was diminished while those in the liver and in other tissues were augmented. These changes were accompanied by a change in the chemical form of bismuth present in the kidneys manifested by the total disappearance of the protein complex of molecular weight of 7000. The increased synthesis of this protein due to bismuth administration was not abolished completely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01891968
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Binding of inorganic mercury by subcellular fractions and proteins of rat kidneys (1976)
    Springer
    Archives of toxicology 37 (1976), S. 57-66 
    Details
    ISSN: 1432-0738
    Keywords: Mercury, inorganic, subcellular distribution ; Mercury, inorganic, biocomplexes
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Anorganisches Quecksilber, Ratten in einer einzelnen Dose von 0,5 mg Hg/kg verabreicht, wurde in den Nieren vorwiegend in der löslichen (54%) und in der Kern-Fraktion (30%) angereichert, und in beiden Fraktionen wurde eine zeitabhängige Abnahme festgestellt. In der mitochondrialen und mikrosomalen Fraktion, in denen zuerst ca. 11 und 6% Quecksilber gefunden wurde, konnte über die erste Woche eine zunehmende Tendenz festgestellt werden. In der löslichen Fraktion waren die metallothionein-ähnlichen Eiweißstoffe von niedrigem Molekulargewicht vorwiegend für die Bindung von Quecksilber verantwortlich. In anderen Zell-Fraktionen war Quecksilber meistens an Eiweiß-stoffe von hohem Molekulargewicht gebunden.
    Notes: Abstract Inorganic mercury, administered to rats in a single dose of 0.5 mg Hg/kg is accumulated in the kidneys mainly in the soluble (54%) and nuclear (30%) fractions, showing decreasing tendency with time. Mitochondrial and microsomal fractions, initially accumulating approx. 11 and 6% of total Hg, show a tendency to increase the absolute level of Hg for the first week after administration. In the soluble fraction low-molecular weight, metallothioneinlike proteins are mainly responsible for the accumulation of mercury, in other fractions proteins of higher molecular weight prevail.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00353355
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  • 4
    Electronic Resource
    Electronic Resource
    The levels of metallothionein-like proteins in animal tissues (1977)
    Springer
    Cellular and molecular life sciences 33 (1977), S. 1624-1625 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The level of metallothionein-like proteins was determined in different tissues of 6 animal species. The highest concentrations were found in pig and rat tissues. The organs richest in metallothionein-like proteins included: kidneys (101–305 μg/g), intestine (127–257 μg/g) and liver (54–496 μg/g).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01934037
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Investigation of65Cu by means of the average resonance proton capture method (1979)
    Springer
    The European physical journal 293 (1979), S. 43-51 
    Details
    ISSN: 1434-601X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The64Ni(p, γ)65Cu reaction has been studied in the proton energy rangeE p =2.05–2.55 MeV. The gamma-ray spectra were recorded with a three-crystal pair spectrometer at proton energy differences of 19 keV covering the proton energy range. An average gamma-ray spectrum was formed by adding all the individual spectra after proper adjustment as a result of the alterations in proton energy. The intensities of the gamma rays to final states with knownJ π-values were tested against theoretical calculations based on the Hauser-Feshbach theory. The gamma-ray strength function for energies lower than 9 MeV has been extracted from the experiment.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01414783
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    Paper (German National Licenses)
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