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  • 1
    Electronic Resource
    Electronic Resource
    Buchbesprechungen (1981)
    Springer
    Helgoland marine research 34 (1981), S. 507-522 
    Details
    ISSN: 1438-3888
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01995922
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  • 2
    Electronic Resource
    Electronic Resource
    Omega-oxidized leukotriene B4 detected in the broncho-alveolar lavage fluid of patients with non-cardiogenic pulmonary edema, but not in those with cardiogenic edema (1991)
    Springer
    Intensive care medicine 17 (1991), S. 1-6 
    Details
    ISSN: 1432-1238
    Keywords: Lung edema ; Acute respiratory distress syndrome ; Leukotrienes ; LTB4 ; Omega-oxidation products of LTB4 ; Broncho-alveolar lavage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Leukotriene (LT) generation has been implicated in the pathogenesis of the acure respiratory distress syndrome, ARDS. In the present study, we analysed broncho-alveolar lavage fluids of patients on mechanical ventilation because of ARDS (17 samples taken from 9 patients) or because of cardiogenic edema (8 samples taken from 6 patients) and of healthy volunteers (10 samples from different donors). LTs were separated as methylated and non-methylated compounds using different HPLC procedures, and were identified by chromatographic mobility, on-line UV-spectrum analysis and post HPLC immunoreactivity. In the lavage samples of the healthy volunteers and the patients with cardiogenic edema, no LTs were detected by these technicues (detection limit≃0.1–0.2 ng/ml lavage fluid). By contrast, in 15 out of 17 samples from patients with ARDS LTB4 or its metabolites 20-OH-LTB4 and 20-COOH-LTB4 were detected. The endproduct of omega-oxidation, 20-COOH-LTB4, represented the quantitatively predominant compound, detected in the range of 0.3–2.6ng/ml perfusate. We conclude that the chemotactic agent LTB4 may be involved in the amplification of inflammatory events encountered in ARDS, and that the oxidized metabolites of LTB4 are particularly suitable for monitoring lung leukotriene generation under conditions of neutrophil efflux and oxidative stress.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01708400
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  • 3
    Electronic Resource
    Electronic Resource
    Imaging of cerebral arterio-venous malformations by transcranial colour-coded real-time sonography (1990)
    Springer
    Neuroradiology 32 (1990), S. 280-288 
    Details
    ISSN: 1432-1920
    Keywords: Transcranial Doppler sonography ; Duplex scanning ; Arterio-venous malformation ; Real-time sonography ; Transcranial color-coded sonography ; MRI
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Transcranial color-coded real-time sonography (TCCS) is a new diagnostic method allowing the non-invasive imaging of parenchymal and vascular structures of the adult brain through the intact skull. A description of the sonographic findings in two patients presenting with a radiologically ascertained arterio-venous malformation is provided. The AVM's can be depicted in the two-dimensional B-mode image as echodense areas interspersed with zones of lower echodensity. Their extension correlated with corresponding MRI images. The color-coded illustration of intravascular flow phenomena allowed the distinct identification of the major afferent feeding vessels, the venous drainage and of the vascular convolution of both AVM's. Information on hemodynamics, as e.g. the blood supply of the angioma by the contralateral internal carotid artery, are obtained by color-coded identification of intravascular flow direction including analysis of the Doppler frequency spectrrum. All findings obtained by TCCS complied with those established by angiography. We conclude, that TCCS is a suitable method for early diagnosis and long term follow up of cerebral AVM's.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00593046
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  • 4
    Electronic Resource
    Electronic Resource
    Reliability of transcranial colour-coded real-time sonography in assessment of brain tumours: correlation of ultrasound, computed tomography and biopsy findings (1994)
    Springer
    Neuroradiology 36 (1994), S. 585-590 
    Details
    ISSN: 1432-1920
    Keywords: Brain tumours ; Ultrasonography ; Computed tomography ; Stereotactic biopsy ; Transcranial colour-coded real time sonography ; Glloma ; Central nervous system ; Duplex sonography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Transcranial colour-coded real-time sonography (TCCS) was carried out in 25 patients with brain tumours to determine whether this noninvasive method provides additional information about the extent of solid tumour, its differentiation from oedema, and its tissue components. All 25 patients had serial computed tomography (CT)-guided stereotactic biopsies. Comparison of ultrasound, CT and histological findings revealed that the vast majority of contrast enhancing areas on CT were hyperechogenic (32/33; 97%) and contained tumour tissue (29/32; 91%). Hyperechogenic areas always represented solid tumour (23/23 patients), even when CT showed low density non-enhancing lesions. In lestons hypoechogenic on TCCS and low density on CT, histology consistently revealed necrotic tumour (7/7). Biopsies obtained from parenchyma with normal echogenicity revealed tumour in only 3 of 16 speciemens. Despite the high specificity of TCCS in the differentiation of tumour components, its sensitivity to tumour was inferior to that of CT (24/25; 96%). TCCS thus allows noninvasive preoperative identification of tumour tissue and its extent setting.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00600414
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  • 5
    Electronic Resource
    Electronic Resource
    Osteoporoseprävention durch postmenopausale Östrogen-Gestagen-Substitution — Langzeitergebnisse und Compliance (1993)
    Springer
    Archives of gynecology and obstetrics 254 (1993), S. 296-297 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02265998
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  • 6
    Electronic Resource
    Electronic Resource
    Wird „Phoenix 3.42“ den Erwartungen gerecht? — Erste Erfahrungen mit einem klinisch-onkologischen Datenverarbeitungsprogramm der neuen Generation (1993)
    Springer
    Archives of gynecology and obstetrics 254 (1993), S. 1145-1146 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02266342
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  • 7
    Electronic Resource
    Electronic Resource
    Movement of thallium(I)-ions across the epithelium of intestinal segments in vitro of rats (1982)
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 321 (1982), S. 157-163 
    Details
    ISSN: 1432-1912
    Keywords: Tl+-ions ; Excretion ; Mucosal epithelium ; Small intestine ; Large intestine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. The movement of Tl+-ions was investigated on both isolated non blood-perfused jejunal and ileal segments as well as on stripped colon segments in vitro of rats. 2. After having administered radioactively labeled 204Tl-(Tl2SO4) on either the mucosal or the serosal side of these preparations only, a preferential direction of the movement of Tl+-ions from the serosal to the mucosal side was observed. In jejunal segments, the 204Tl-radioactivity at the mucosal side reached a concentration equilibrium with the concentration administered at the serosal side of the preparations. In colon segments a concentration gradient of more than 2 was established between the mucosal and the serosal side. In ileal segments the concentration of 204Tl-radioactivity in the mucosal fluid reached roughly 80% of that administered at the serosal side. 3. The amount taken up into the intestinal tissue is much higher after having administered the 204Tl-radioactivity from the serosal side than from the mucosal side. This holds true for jejunal ileal, and colonic segments. 4. In equilibrium experiments of non-everted colonic segments which were incubated on either side with the same 204Tl-concentrations the net transfer of 204Tl was determined directly. After a delay of 60 min the net transfer of 204Tl follows the rapid uptake into the intestinal tissue. 5. The net transfer as well as the tissue content of 204Tl decreases with increasing concentrations. From concentrations of 204Tl-ions of 5×10-5M on, no concentration gradient between the mucosal and the serosal side could be established. 6. The net transfer of 204Tl depends highly on temperature. At 29°C a diminished concentration gradient of the 204Tl between the mucosal and the serosal fluid was observed. At 25°C no concentration gradient could be established. The content of 204Tl in tissue, however, was not affected by this decrease of temperature. 7. The net transfer of 204Tl is nearly doubled by an increase of the K+-concentration at the mucosal side from 4.5 (normal) up to 72 mM, whereas the change of the 204Tl-content in tissue was statistically not significant. A decrease, however, of the net transfer of 204Tl is the consequence of an increased K+-concentration at the serosal side. In these segments the 204Tl content in tissue is decreased by 16% at the highest concentration of K+-ions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00518485
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  • 8
    Electronic Resource
    Electronic Resource
    A new concept for the assessment of the oxygen situation in a shelf sea area (1994)
    Springer
    Ocean dynamics 46 (1994), S. 263-275 
    Details
    ISSN: 1616-7228
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Description / Table of Contents: Zusammenfassung Die Sauerstoff-Bedingungen in der unteren Wasserschicht eines Schelfmeeres werden im allgemeinen durch die O2-Konzentration dicht über dem Meeresboden charakterisiert, weil diese für die Boden-Organismen besonders wichtig ist und am Boden häufig O2-Mangel herrscht. Für andere Umwelt-Aspekte muß man die gesamte Wassersäule in die Betrachtung einbeziehen. Daher wird ein neuer Sauerstoffmangel-Index vorgeschlagen. Er ist definiert durch das Sauerstoff-Defizit in der Schicht zwischen dem Meersboden und der Tiefe mit 100% O2-Sättigung. Beide Indexe ergänzen einander. Sie können angewendet werden a) zur Beurteilung der aktuellen Sauerstoff-Situation b) zur Erkennung von zeitlichen Veränderungen und Trends c) zum Vergleich der der Sauerstoff-Bedingungen in verschiedenen Gebieten. Zum Vergleich von Stationen mit unterschiedlichen Wassertiefen wird der Sauerstoffmangel-Index auf die Wassertiefe bezogen. Die Indexe werden anhand von praktischen Beispielen aus der südwestlichen Ostsee erläutert.
    Notes: Summary Usually, the oxygen conditions in the lower water layer of a shelf sea area are characterized by the oxygen concentration immediately above the bottom, because this concentration is essential for the bottom living organisms, and as there may be a high oxygen demand due to benthic respiration For other environmental aspects, however, the vertical distribution in the whole water column must be taken into account. So, a new oxygen deficiency index is proposed. It is difined by the oxygen deficit in the layer between the bottom and the depth witl: 100% oxygen saturation, Both indexes complement each other. They can be used for a) Characterizing the actual oxygen situation, b) recongnizing temporal changes and trends, c) comparing the oxygen conditions in different areas. For comparison of stations with different depths, the oxygen dificiency index is related to (=divided by) the water depth. Some examples are given for temporal variations and trends and for spatial differences of the oxygen situation in the south-western Baltic Sea.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02226954
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  • 9
    Electronic Resource
    Electronic Resource
    Über die analytische Bestimmung der Vitamine A, B1, B2 und C (1939)
    Springer
    Fresenius' Zeitschrift für analytische Chemie 117 (1939), S. 284-297 
    Details
    ISSN: 1618-2650
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01470729
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  • 10
    Electronic Resource
    Electronic Resource
    Neuere Veröffentlichungen (1981)
    Springer
    Ocean dynamics 34 (1981), S. 38-40 
    Details
    ISSN: 1616-7228
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02227004
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