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  • 1
    Electronic Resource
    Electronic Resource
    Glomerular disease of transplanted kidneys (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 840-842 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00190333
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  • 2
    Electronic Resource
    Electronic Resource
    Treatment of acute postoperative renal failure after liver and heart transplantation by urodilatin (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 435-436 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180055
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  • 3
    Electronic Resource
    Electronic Resource
    Kidney transplantation from cadaveric donors versus living related donors: improved results in the cyclosporine era (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 621-621 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00184488
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  • 4
    Electronic Resource
    Electronic Resource
    Influence of antihypertensive therapy on renal function (1992)
    Springer
    Journal of molecular medicine 70 (1992), S. S120 
    Details
    ISSN: 1432-1440
    Keywords: Hypertension ; Kidney ; Antihypertensive drugs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Antihypertensive therapy influences kidney function by different mechanisms depending on the mode of action of the drug used. The GFR is improved by calcium entry blockers and ACE inhibitors, unaffected by vasodilators, α-blockers and centrally acting sympatholytics and impaired by β-blockers. The same is true for renal blood flow and is due to changes of renal vascular resistance. Renal sodium excretion is impaired mostly by vasodilators, by α-blockers, sympatholytics and β-blockers; in contrast, calcium entry blockers and ACE inhibitors acutely induce natriuresis. The RAAS is stimulated by vasodilators, unaffected by α-blockers and sympatholytics and suppressed by β-blockers. Plasma catecholamines are stimulated by vasodilators and suppressed by centrally acting sympatholytics and unaffected by the others. Induction of acute renal functional impairment is reported for ACE inhibitors under conditions of compromised renal perfusion pressure such as in renal artery stenosis. These data from the literature reviewed are supported by our own experimental data on sodium balance under different drugs and micropuncture data in experimental renal artery stenosis. To achieve effective antihypertensive treatment with a low profile of side effects, careful monitoring of renal function seems to be mandatory.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00207622
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  • 5
    Electronic Resource
    Electronic Resource
    Disseminated tuberculosis after renal transplantation (1990)
    Springer
    Transplant international 3 (1990), S. 113-115 
    Details
    ISSN: 1432-2277
    Keywords: Tuberculosis ; in renal transplantation — Renal transplantation ; tuberculosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Disseminated mycobacterial infections occurred in two female renal graft recipients late after transplantation. In the first patient, initially presenting with fever, diagnosis was made at autopsy. Temporary defervescence following antibiotic therapy with ofloxacin possibly contributed to the fatal diagnostic delay. In the second case, body temperature was normal throughout the protracted course of the patient's illness. Her presenting symptom was rapidly increasing ascites, attributed initially to chronic liver disease. These cases demonstrate that tuberculosis remains a serious complication after renal transplantation, in particular due to its sometimes atypical clinical manifestations. Response to antibacterial therapy has to be critically evaluated in order to avoid fatal diagnostic delay.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00336215
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  • 6
    Electronic Resource
    Electronic Resource
    Somatic fusion for combining virus resistances in Solanum tuberosum L. (1993)
    Springer
    Theoretical and applied genetics 85 (1993), S. 863-867 
    Details
    ISSN: 1432-2242
    Keywords: Potato ; PYX ; PVY ; Protoplasts ; Somatic hybrids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Dihaploid genotypes of potato, containing the dominant allele for extreme resistance to PVX and/or PVY, were used in a fusion program in order to analyze the behaviour of the two monogenetic resistances after fusion. Eighteen different fusion combinations were performed and regenerated hybrids were tested by ELISA for their virus resistance. In most of the combinations an addition of the two qualities was found, but a few deviating clones were observed. The possible reasons for the phenotypic disappearance of resistant alleles are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225030
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  • 7
    Electronic Resource
    Electronic Resource
    Field evaluation of tetraploid somatic potato hybrids (1994)
    Springer
    Theoretical and applied genetics 88 (1994), S. 147-152 
    Details
    ISSN: 1432-2242
    Keywords: Solanum tuberosum ; Somatic hybrids ; Field evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Tetraploid somatic hybrids, derived from ten different fusion combinations, were grown in the field to study the inheritance of quantitatively-controlled agronomic traits. The data from two seasons showed that the heterosis in yield varied between 70% and 230% compared to the mid-parent value of the dihaploid fusion clones. The relative yield of the hybrids compared to two standard varieties (= 100%) ranged from 47% to 106%. Despite large differences in yield between the single hybrids of the same fusion combination, no significant differences could be detected between the hybrids. The analysis of the yield components revealed that the heterosis was mainly due to a highly increased tuber weight, whereas the tuber number was in general intermediate to that of the parent clones. In three combinations, the starch content of the hybrids was 15–20% higher than the midparent value and in the others it was intermediate. Fusion of clones with long oval tubers and with round or round-oval ones showed the round/round-oval form was dominant. Fusion combinations of tuber flesh colour indicated that in most cases yellow was dominant to white, while red skin colour was dominant over yellow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225890
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  • 8
    Electronic Resource
    Electronic Resource
    Interaction between cytoplasmic composition and yield parameters in somatic hybrids of S. tuberosum L. (1994)
    Springer
    Theoretical and applied genetics 89 (1994), S. 873-878 
    Details
    ISSN: 1432-2242
    Keywords: Potato ; Somatic fusion ; Cytoplasm Starch ; Variability ; Field evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The nuclear and cytoplasmic composition of five different fusion combinations, consisting of up to 50 hybrid regenerants each, was characterized by RFLP analysis. Simultaneously, the hybrid clones of four fusion combinations were evaluated in field experiments for yield and starch content. Predominantly complete chloroplast segregation was found with a 1∶1 ratio, in all but one fusion combination. Mitochondria, in contrast revealed up to 75% recombination, as proven by the partial addition of parental banding patterns and the altered assignment of the same genotypes with different probes. Newly occuring DNA bands were also indicative of rearrangements in the mitochondrial genome. Correlations between RFLP data and field parameters were calculated. Deviating RFLP patterns of the nuclear genome did not influence yield parameters. Also the assignment of hybrids to different chloroplast genotypes did not affect yield or starch content. However, mitochondrial types could be distinguished with respect to starch content and tuber yield. The more thorough analysis of mitochondrial composition, with different probes homologous to coding regions, revealed a relationship between the homogeneity of the mt genome and the yield level.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224512
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