Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    Attachment of rhodosaminylanthracyclinone-type anthracyclines to the hinge-region of monoclonal antibodies (1990)
    s.l. : American Chemical Society
    Bioconjugate chemistry 1 (1990), S. 100-107 
    Details
    ISSN: 1520-4812
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bc00002a003
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Regulation of monocyte and keratinocyte interleukin 6 production by transforming growth factor β (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Experimental dermatology 3 (1994), S. 0 
    Details
    ISSN: 1600-0625
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract There is strong evidence for a complex network-like interaction between cytokines, growth factors and other mediators being responsible for cell growth and differentiation as well as for the outcome of an inflammatory reaction. Therefore, the regulation of the production of the ubiquitous proinflammatory cytokine interleukin 6 (IL-6) by transforming growth factor β (TGFP) was investigated. Human peripheral blood mononuclear cells (PBMC), human normal keralinocytes (HNK), and an epidermoid carcinoma cell line (KB) were treated with TGFβ or TGFβ2 and subsequently IL-6 secretion was evaluated. Addition of TGFβ1 as well as TGFβ2 to PBMC, HNK and KB cells resulted in a significantly increased release of IL-6 activity. The inducing effect of TGFβ was dose dependent and maximal when supernatants were harvested 48 h after stimulation. In addition, upon Western blot analysis using a monoclonal IL-6 antibody significantly increased amounts of IL-6 protein were detected in KB cell supernatants following stimulation with TGFβ 1. These results were further confirmed at the transcriptional level using a cDNA probe specific for IL-6 and Northern blot analysis. Accordingly, an increased IL-6 inRNA expression in PBMC or KB cells was detected following TGFβl treatment. These findings indicate that TGFβ in contrast to its antiinflammatory capacities also may stimulate IL-6 production in PBMC and keratinocytes. This further supports the possibly important immunoregulatory role of growth factors such as TGFβ.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0625.1994.tb00294.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Production of Immunosuppressing Melanotropins By Human Keratinocytes (1993)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 680 (1993), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1993.tb19741.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Protecting Groups for the Enzymatic Peptide Synthesis (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 613 (1990), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1990.tb18235.x
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 5
    Electronic Resource
    Electronic Resource
    Long-term effects of steroid withdrawal in kidney transplantation (1993)
    Springer
    Transplant international 6 (1993), S. 290-292 
    Details
    ISSN: 1432-2277
    Keywords: Steroid withdrawal, kidney transplantation ; Kidney transplantation, steroid withdrawal ; Conversion, steroid to azathioprine, kidney transplantation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The long-term graft function after withdrawal of steroids from maintenance immunosuppression was analyzed in 98 kidney recipients (59 on cyclosporin monotherapy, 39 on cycloporin plus azathioprine) who had not developed an early rejection episode when prednisolone was discontinued. Seven years after steroid withdrawal the probability of an increase in serum creatinine (〉20% of baseline levels) was 51%. The increase in creatinine was associated with sclerosing arteriopathy as a marker of chronic rejection in 29 of 43 graft biopsies. The addition of azathioprine had no, effect on the stability of long-term graft function and did not influence the 7-year graft survival rate in this highly selected group of patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00336030
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 6
    Electronic Resource
    Electronic Resource
    Endothelin excretion during ketoacidosis does not correlate with tubular dysfunction (1994)
    Springer
    Pediatric nephrology 8 (1994), S. 304-308 
    Details
    ISSN: 1432-198X
    Keywords: Endothelin ; Diabetes ; Ketoacidosis ; Tamm-Horsfall protein ; α1-Microglobulin ; Glomerular filtration rate ; Diuresis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Urinary excretion of endothelin was measured by radioimmunoassay in children with diabetes mellitus during severe ketoacidosis and 12 days later when blood pH and blood glucose concentrations were normal. Metabolically stable diabetic children served as controls. Results from apparently healthy children without diabetes mellitus were used as normal values. Renal tubular injury was evaluated by the urinary excretion of the proximal tubular marker α1-microglobulin and the distal tubular marker Tamm-Horsfall protein (THP). During ketoacidosis we detected a decreased glomerular filtration rate associated with highly significant changes in the excretion of α1-microglobulin, indicating proximal tubular damage, and THP, suggesting disturbance of cells of the ascending loop of Henle. The daily excretion of endothelin was unaltered but the ratio of endothelin/creatinine or endothelin excretion/creatinine clearance were significantly enhanced. In conclusion, we could demonstrate that, despite a proximal and distal tubular cell dysfunction, endothelin excretion when related to creatinine clearance may be a consequence of disturbed proximal tubular function or dysfunction of the renal medulla.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00866342
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 7
    Electronic Resource
    Electronic Resource
    Virasoro model space (1990)
    Springer
    Communications in mathematical physics 134 (1990), S. 539-554 
    Details
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract The representations of a compact Lie groupG can be studied via the construction of an associated “model space.” This space has the property that when geometrically quantized its Hilbert space contains every irreducible representation ofG just once. We construct an analogous space for the group DiffS 1. It is naturally a complex manifold with a holomorphic, free action of DiffS 1 preserving a family of pseudo-Kahler structures. All of the “good” coadjoint orbits are obtained from our space by Hamiltonian constraint reduction. We briefly discuss the connection to the work of Alekseev and Shatashvili.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02098446
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 8
    Electronic Resource
    Electronic Resource
    Supermoduli spaces (1990)
    Springer
    Communications in mathematical physics 135 (1990), S. 91-100 
    Details
    ISSN: 1432-0916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics , Physics
    Notes: Abstract The connection between different supermoduli spaces is studied. It is shown that the coincidence of the moduli space of (1/1) dimensional complex manifolds andN=2 superconformal moduli space is connected with hiddenN=2 superconformal symmetry in the superstring theory.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02097658
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 9
    Electronic Resource
    Electronic Resource
    Terrestrial vegetation at Canada Glacier, Southern Victoria Land, Antarctica (1992)
    Springer
    Polar biology 12 (1992), S. 397-404 
    Details
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Bryophyte flushes in the vicinity of Canada Glacier in S.S.S.I. No. 12, Taylor Valley, Southern Victoria Land, were investigated in order to describe the vegetation present and to investigate factors affecting vegetation distribution. Biomass values from 950 to 1,250 g m−2 (dry weight) and vegetated areas up to 14,450 m2 indicate this is a significant area of bryophyte growth in Southern Victoria Land. The pattern of plant species in relation to water flow was investigated through detailed mapping. This is the first confirmed identification of Bryum argenteum, and Pottia heimii, and the first report of Bryum pseudotriquetrum from this area. Tissue nitrogen values for plants at this site are lower than other reported data, but it seems unlikely this would be a limiting factor for growth. It is concluded that, in this area, summer water flow in conjunction with microtopography has the greatest influence in determining where mosses, cyanobacteria and algae grow.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00243110
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 10
    Electronic Resource
    Electronic Resource
    Invertebrates associated with moss communities at Canada Glacier, southern Victoria Land, Antarctica (1993)
    Springer
    Polar biology 13 (1993), S. 157-162 
    Details
    ISSN: 1432-2056
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The invertebrate faunal composition of moss-dominated flushes near the Canada Glacier was, as in similar habitats in continental Antarctic regions, numerically dominated by protozoa, rotifers, nematodes and tardigrades. Mites were of lesser abundance. Although collembola occur in the Taylor Valley, none were found at the study site. The finding of a catenulid flatworm is significant as microturbellarians have only rarely been recorded from Antarctica. Nematode, tardigrade and rotifer densities recorded were comparable to those in other Antarctic regions. These groups were found at a mean depth ranging from 5 to 10.83 mm in the moss. A greater percentage of all groups were in the upper 5 mm of moss cores in post-melt samples than in pre-melt samples.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00238925
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...