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  • 1990-1994  (2)
  • Diffuse peritonitis  (1)
  • Lamprey, Geotria australis (Cyclostomata)  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 265 (1991), S. 447-457 
    ISSN: 1432-0878
    Keywords: Gills ; Chloride cells ; Tight junctions ; Seawater adaptation ; Osmoregulatory function ; Lamprey, Geotria australis (Cyclostomata)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Thin sections and freeze-fracture replicas have been used to study the structure of the zonulae occludentes of the branchial chloride cells in young adults of the anadromous lamprey Geotria australis, caught during their downstream migration to the sea and after acclimation to full-strength seawater (35‰). The chloride cells in the epithelium of the gill filaments of both freshwater- and seawater-acclimated animals form extensive multicellular complexes. In freshwater animals, the majority of chloride cells (64%) are covered by pavement cells and are thus not exposed to the external environment. Most of the other chloride cells are separated from each other by pavement cells or their processes. The zonulae occludentes between chloride cells and pavement cells and between adjacent chloride cells are extensive and characterised by a network of 4 (range 3–7) superimposed strands. In seawater-acclimated animals, the pavement cells cover only 30% of the chloride cells and their processes no longer occur between chloride cells. Whereas the zonulae occludentes between chloride cells and pavement cells are still extensive, those between chloride cells are shallow and comprise only a single strand or two parallel strands. The zonulae occludentes between the chloride cells of lampreys acclimated to seawater are similar to those in the gills of teleosts in seawater, and are thus considered to be leaky and to provide a low-resistance paracellular pathway for the passive transepithelial movement of Na+.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 377 (1992), S. 89-93 
    ISSN: 1435-2451
    Keywords: Diffuse peritonitis ; Programmed relaparotomy ; Prognostic factors ; Univariate, multivariate analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Anhand cities Patientenkollektivs von 184 Patienten mit diffuser Peritonitis wurden 46 Variablen in einer uni- und multivariaten Analyse auf ihre prognostische Relevanz für das Überleben der Patienten überprüft. Dabei zeigten in der univariaten Analyse folgende Parameter eine signifikante Korrelation mit dem Verlauf: Lebensalter ≥70 Jahre, heptatogene und kardiale Vorerkrankung, nicht erfolgte Fokussanierung bei 1. Operation wegen Peritonitis, Kreislaufinstabilität, pulmonales Versagen, Hyperbilirubindmie, Thrombozytopenie, erhöhtes Serumkreatinin und eingeschränkte Kreatinin-Clearance zu Behandlungsbeginn sowie der Nachweis von Pseudomonas aeruginosa im Peritonealexsudat und von Candida albicans hämatogen im Therapie verlauf. In der multivariaten Analyse erwiesen sich in hierarchischer Ordnung die chirurgische Fokussanierung bei der 1. Laparotomie wegen Peritonitis, das Serumkreatinin bei Krankheitsbeginn, Patientenalter ≥70 Jahre und die hepatogene Vorerkrankung als unabhängige Variable mit signifikanter prognostischer Relevanz für das Überleben der Patienten.
    Notes: Summary In order to evaluate their prognostic relevance for survival 46 variables were submitted to univariate as well as multivariate analysis in a group of 184 patients with diffuse peritonitis. In the univariate analysis a significant correlation with the outcome was found for the following parameters: age ≥ 70 years, preexisting hepatic or cardiac disease, no eradication of the primary source of infection at first laparotomy for peritonitis, cardiovascular instability, respiratory failure, hyperbilirubinemia, thrombocytopenia, elevated serum creatinine and diminished creatinine clearance at the beginning and proof of pseudomonas aeruginosa in the peritoneal exsudate and of candida albicans in the blood culture during the course of the peritonitis. In the multivariate analysis the surgical eradication of the primary source of infection at the first laparotomy for peritonitis, serum creatinine at the beginning of peritonitis, age ≥ 70 years and a preexisting hepatic disease proved to be the independent variables with significant prognostic relevance for survival of the patients.
    Type of Medium: Electronic Resource
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