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  • 1
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    Madrid : Periodicals Archive Online (PAO)
    Revista de filología española. 11 (1924) 193-196 
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  • 2
    ISSN: 1434-4475
    Keywords: Complexes ; Gold(III) ; Theophylline ; Trimethylxanthine
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Es wurden Komplexe der generellen Formel AuLCl2 (wobeiL jeweils die deprotonierten Formen von Theophyllin, 1,3,8-Trimethylxanthin, 8-Ethyltheophyllin, 8-Isopropyltheophyllin und 8-Pentyltheophyllin sind) hergestellt und mittels spektroskopischer (IR,1H-NMR) und thermischer Methoden (TG, DSC) charakterisiert. Die experimentellen Daten legen nahe, daß alle Komplexe eine polymere Struktur aufweisen, wobei die entsprechenden Theophyllin-Derivate als Monoanionen wirken, die an die benachbarten Au(III)-Ionen über beide Imidazol-Stickstoffatome gebunden sind. Die Struktur der Monomeren scheint quadratisch-planar zu sein, wobei die Chloratome intrans-Positionen an das Metall-Ion gebunden sind.
    Notes: Abstract Complexes with the general formula AuLCl2, whereL are the deprotonated forms of theophylline, 1,3,8-trimetylxanthine, 8-ethyl-theophylline, 8-isopropyl-theophylline and 8-pentyl-theophylline, have been synthesized and characterized by spectral (IR and1H-NMR) and thermal methods (TG and DSC). Experimental data suggest that all of them present a polymeric structure, in which the corresponding theophylline derivative acts as a monoanion, bonding to contiguous Au(III) ions through both imidazole nitrogen atoms. The structure of the monomer seems be square-planar, with the chlorine atoms linked to metal ion intrans positions.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1420-9071
    Keywords: Aspilia ; chimpanzees, feeding behavior ; thiarubrine A
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Two African species ofAspilia (Asteraceae), which are used medicinally by man and which are eaten by wild chimpanzees in an unusual manner, were found to contain the potent antibiotic thiarubrine A as a major leaf phytochemical. Its presence in leaf material strengthens the view that the feeding behavior of wild chimpanzees is related to special physiological or pharmacological effects on the animals.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Histochemistry and cell biology 84 (1986), S. 31-40 
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The ontogenetical development of the subcommissural organ (SCO) was investigated in chick embryos collected daily from the 1st to the 21st day of incubation. Some duck embryos, and adult chickens and ducks were also studied. Immunocytochemistry using an anti-Reissner's fiber (RF) serum as the primary antibody was the principal method used. In the chick embryos the events occurring at different days of incubation were: day 3 morphologically undifferentiated cells in the dorsal diencephalon displayed immunoreactive material (IRM); days 4 to 6 immunoreactive cells proliferated, formed a multilayered structure and developed processes which traversed the growing posterior commissure and ended at the brain surface; day 7 i) blood vessels penetrated the SCO, ii) scarce hypendymal cells appeared, iii) the first signs of ventricular release of IRM were noticed, iv) appearance of IRM bound to cells of the floor of the Sylvius aqueduct; day 7 to 10 the number of apical granules and amount of extracellular IRM increased progressively; day 11 RF was observed along the Sylvian aqueduct; day 12 RF was present in the lumbar spinal cord; day 13 IRM on the aqueductal floor disappeared; days 10 to 21 i) hypendymal cells proliferated, developed processes and migrated dorsally, ii) ependymal processes elongated and their endings covered the external limiting membrane. In adult specimens the ependymal cells lacked basal processes and the external membrane was contacted by hypendymal cells. The duck SCO appears to follow a similar pattern of development.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Three straining protocols for the ultrastructural visualization of concanavalin A (ConA) and wheat germ agglutinin (WGA) binding sites were applied to samples of nervous tissue embedded in Lowicryl K4M. The hypothalamo-neurohypophysial neurosecretory system was chosen for this investigation because it has two major neuronal populations, one secreting vasopressin, whose precursor is glycosylated, and the other secreting oxytocin whose precursor form is not glycosylated. The series of incubations of the tissue sections for the three protocols were: Protocol 1: i) non labeled ConA or WGA; ii) ConA or WGA antibody; iii) protein A-gold; Protocol 2: i) pre-prepared WGA-anti-WGA complex; ii) protein A-gold; Protocol 3: i) peroxidase-labeled ConA or WGA; ii) anti-peroxidase; iii) protein A-gold. The three methods allowed to detect fine differences in the distribution of sugar residues. This, in turn, made it possible to distinguish vasopressin granules containing precursor forms from those containing processed precursor. At the light microscopic level the three methods were successfully applied to paraffin and 1-μm methacrylate sections by using a second antibody, PAP complex and the diaminobenzidine reaction.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-119X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary In the snake, Natrix maura, and the turtle, Mauremys caspica, the basal processes of the ependymal cells of the subcommissural organ project toward the local blood vessels and the leptomeninges. These processes and their endings were studied using aldehyde-fuchsin (AF), periodicacid Schiff (PAS), periodic-acid silver-methenamine (PASM), concanavalin A (ConA), wheat germ agglutinin (WGA), immunoperoxidase staining (employing an antiserum against bovine Reissner's fiber; AFRU), and conventional transmission electron microscopy. For the purposes of comparison, the ventricular cell pole was also analyzed. The secretory material located in the ventricular cell pole and that present in ependymal endings had only a few staining properties in common, i.e., affinity for AF, ConA, and AFRU at a dilution of 1:1000. On the other hand, PAS, PA-SM, WGA, and AFRU at a dilution of 1:200 000 stained the apical (ventricular) secretory material but not the secretory material of the ependymal processes. The histochemical features of the secretory material located in the terminals of ependymal processes, as well as the presence at these sites of numerous rough-endoplasmic-reticulum cisternae and secretory granules, suggest that secretory material may by synthesized in these terminals. The probable fate of this material, i.e., release to the perivascular and leptomeningeal spaces or transport to the ventricular cell pole, is discussed.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1572-8943
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Das thermische Verhalten von 6-Amino-5-formyluracil (HFU), 6-Amino-1-methyl-5-formyluracil (1-HFU), 6-Amino-3-methyl-5-formyluracil (3-HFU) und 6-Amino-1,3-dimethyl-5-formyluracil (HDFU) wird beschrieben. Nur HDFU enthält Kristallwasser. Dehydratisierungs- und Schmelzenthalpiewerte wurden aus den DSC-Kurven berechnet. Auch über das thermische Verhalten neuer, durch Reaktion der obigen Pyrimidin-Derivate mit Ni(II)-, Cu(II)- und Pd(II)-Ionen erhaltenen Komplexe wird berichtet.
    Abstract: Резюме Описано термическое поведение 6-амино-5-форм ил-, 6-амино-1-метил-5-формил-, 6а мино-З-метил-5-формили 6-амино-1,3-диметил-5-форми лурацилов. Показано, ч то только последнее соединени е содержит кристалли зационную воду. На основе кривых ДСК вычислены значения энтальпии д егидратации и плавле ния. Подобным образом изу чено также термическ ое разложение комплекс ов вышеприведенных п роизводных пиримидина с двухвал ентными никелем, медью и палла дием.
    Notes: Abstract The thermal behaviour of 6-amino-5-formyluracil (HFU), 6-amino-1-methyl-5-formyluracil (1-MFU), 6-amino-3-methyl-5-formyluracil (3-HFU) and 6-amino-1,3-dimethyl-5-formyluracil (HDFU) is described. Only HDFU is shown to contain crystallization water. Dehydration and fusion enthalpy values have been calculated from the DSC curves. Likewise, the thermal behaviour of new complexes obtained by reaction between the above pyrimidine derivatives and Ni(II), Cu(II) and Pd(II) ions is reported.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Journal of thermal analysis and calorimetry 30 (1985), S. 771-779 
    ISSN: 1572-8943
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Zusammenfassung Tetrachloroaurate von 8-Äthyl-, 8-Isopropyl-, 8-Propyl- und 8-Pentyltheophillin wurden synthetisiert und mittels1H-NMR, TG und DSC untersucht. Die 8-Alkyltheophillin-Derivate sind nicht koordinativ an das Metall gebunden, es liegt vielmehr eine salzartige Struktur vor.
    Abstract: Резюме Синтезированные тет рахлороаураты 8-этил-, 8-пропил-, 8-изопропил- и 8-п ентилтеофиллина были изучены методам и ПМР, ТГ и ДСК. Установлено, что мета лл не координирован с 8-алкилтеофиллинами и соединения имеют сол еобразную структуру.
    Notes: Abstract Tetrachloroaurates of 8-ethyl-, 8-isopropyl-, 8-propyl- and 8-pentyltheophylline were synthesized and studied by1H-NMR, TG and DSC techniques. The metal is not coordinated to the 8-alkyltheophylline derivatives and forms a salt-like structure.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Journal of materials science 22 (1987), S. 1934-1940 
    ISSN: 1573-4803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The temperature changes as a result of rapid hydrostatic pressure applications are reported for high density polyethylene (HDPE) and low density polyethylene (LDPE) in the reference temperature range from 298 to 423 K and in the pressure range from 13.8 to 200 MN m−2. The adiabatic temperature changes were found to be a function of pressure and temperature. A curve fitting analysis showed that the empirical curve (∂/∂P) =ab(ΔP)b−1 described the experimental thermoelastic coefficients obtained from the experiments. The data were analyzed by determining the predicted thermoelastic coefficients derived from the Thomson equation (∂/∂P)θ = αT 0/ϱC p. The experimental and predicted Grüneisen parameter γ T were also determined.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-0878
    Keywords: Subcommissural organ ; Secretory activity, neural control ; Transplantation ; Long-spacing collagen ; Immunocytochemistry ; Molecular markers (neuronal, glial) ; Electron microscopy ; Rat (Sprague-Dawley)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary There is increasing evidence that, in the rat, a serotonin-mediated neural input may have an inhibitory influence on the secretory activity of the subcommissural organ (SCO). In the present investigation the rat SCO was studied 7, 30 and 90 days after transplantation under the kidney capsule, an area devoid of local serotonin-containing nerves. The grafted tissue was examined by use of immunocytochemistry employing a series of primary antisera, lectin histochemistry and transmission electron microscopy. The grafted SCO survived transplantation and contained, in addition to secretory ependymal and hypendymal SCO-cells, also elements immunoreactive with antisera against glial fibrillary acidic protein or S-100 protein. In transplants, SCO-cells produced a material displaying the characteristic immunocytochemical and lectin-binding properties of SCO-cells observed under in-situ conditions. The ependymal cells lined 1–3 small cavities, which contained secretory material. A fully developed structural equivalent of Reissner's fiber was, however, never found. The immunocytochemical and ultrastructural study of the grafted SCO showed an absence of nerve fibers within the graft and suggested a state of enhanced secretory activity. A network of protruding basal lamina structures connected the secretory cells to the newly formed capillaries revascularizing the SCO. One week after transplantation, long-spacing collagen started to appear in expanded areas of such laminar networks and also in the perivascular space. It is suggested (i) that the formation of long-spacing forms of collagen is triggered by factors provided by the SCO-secretory cells, and (ii) that secretory material of the ependymal and hypendymal cells may reach the reticular extensions of the basal lamina. In contrast to the SCO in situ, the grafted SCO-cells showed a positive immunoreaction for neuron-specific enolase. They became surrounded by a S-100-immunoreactive glial sheath that separated them from other transplanted cell types and the adjacent kidney tissue of the host.
    Type of Medium: Electronic Resource
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