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  • 1985-1989  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of molecular medicine 63 (1985), S. 93-94 
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1437-3262
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Description / Table of Contents: Abstract The Brazilian Coastal Mobile Belt in southern Espírito Santo consists of Archean to Upper Proterozoic units which have been metamorphosed and deformed to a gneiss, migmatite and granulite-facies rock assemblage during Archean and Proterozoic tectono-thermal events. Several tectonic phases and an amphibolite-facies metamorphism are attributed to the Brasiliano-Event (680-450 Ma). Towards the end of the Brasiliano-Cycle diapirically ascending basic to intermediate and acid magmas intruded the lower crust, forming numerous concordant plutons. A model is presented for the Santa Angélica intrusion: A mantle derived basic magma, probably a fractionated alkali or transitional basalt, intruded the lower crust and induced anatectic melting and production of granitic melts. Intensive mechanical mixing of basic and granitic magma during ascent through buoyant and/or forced convection led to a wide variety of hybrid rocks. The structures suggest liquid-solid and liquid-liquid, or mushy-mushy interaction of the contrasting magmas. Different stages of mechanical mixing and homogenization are preserved, now representing »frozen-in« magma mixing features.
    Abstract: Resumen El cinturon orogénico costero brasilero en el sur del estado de Espírito Santo contiene unidades arcaicas hasta proterozoicas superiores, las cuales fueron transformados en gneises, migmatitas y rocas de la facies granulita y altamente deformadas por eventos téctono-termales del Arcaico y Proterozoico. Al Evento Brasiliano (680-450 Ma) se le atribuyen varias fases tectónicas bajo condiciones de metamorfismo de facies de anfibolita. Hacia el final del Ciclo Brasiliano se efectuó la ascensión diapírica de magmas básicos/intermedios a ácidos bajo la formación de varios plutones concordantes en profundos niveles de la corteza. Se presenta un modelo de intrusión para el plutón de Santa Angélica: Magma básico proveniente del manto induce magma granítico anatéctico en la corteza inferior. El magma básico es considerado un producto de cristallisación fraccionada de un basalto alcalino o transicional. La intensiva mezcla mecánica durante la ascensión a consecuencia de »buoyant« y/o »forced convection« condujo a la formación de rocas híbridas en su mas amplo espectro. Las estructuras observadas en estas rocas se deben a reacciones líquidosólido, líquido-líquido y »mushy-mushy« entre ambos magmas. Los mas diversos estadios de la mezcla mecánica y de la homogeneisación fueron conservados. Actualmente se encuentra el »magma-mixing« en un estadio de »congelamiento«.
    Notes: Zusammenfassung Der Brasilianische Küstenfaltengürtel im südlichen Espírito Santo beinhaltet archaische bis oberproterozoische Einheiten, die durch tektono-thermale Ereignisse des Archaikums und Proterozoikums in hochdeformierte Gneise und Migmatite umgewandelt wurden. Dem Brasiliano-Ereignis (680–450 Ma) werden mehrere tektonische Phasen unter amphibolitfaziellen Metamorphosebedingungen zugeordnet. Gegen Ende des Brasiliano-Zyklus' erfolgte der diapirische Aufstieg basisch/intermediärer bis saurer Magmen in tiefere Krustenstockwerke unter Bildung konkordanter Plutone. Für den Santa Angélica Pluton wird ein Intrusionsmodell vorgestellt: Basisches Magma aus dem Mantel, das als Fraktionierungsprodukt eines Alkalioder Transitionalbasaltes angesehen wird, induziert anatektische Granitschmelzen in der Unterkruste. Intensive mechanische Durchmischung während des Aufstieges infolge »buoyant« und/oder »forced convection« führt zur Bildung eines weiten Spektrums von Hybridgesteinen. Die darin beobachteten Strukturen sind auf »Flüssig-Fest«- und »Flüssig-Flüssig«-Reaktionen zwischen den beiden verschiedenen Magmen zurückzuführen. Es sind die verschiedensten Stadien der mechanischen Durchmischung und Homogenisierung erhalten. Auf diese Weise ist die Magmenmischung heute in »eingefrorenem« Zustand erhalten.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-2568
    Keywords: human ; stomach ; duodenum ; mucosa ; prostaglandin synthesis ; antacids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Using14C-labeled arachidonic acid as precursor for in vitro prostaglandin synthesis, the effect of an antacid containing Al (OH)3, Mg(OH)2 and CaCO3 on endogenous prostaglandin synthesis was investigated in antral and duodenal mucosa of healthy volunteers. After three weeks of treatment with a high-dose antacid, there was no detectable change in the total capacity of the mucosa for prostaglandin synthesis, but the prostaglandin profile was markedly altered. The relative amounts of PGE2 and PGF2α synthesized by antral and duodenal mucosa increased at the expense of the prostaglandinsA2/B2, thromboxane A2, and prostacyclin. In a short-term study, this change was not observed following a single antacid dose within 1 hr after application. It is concluded that long-term antacid treatment may alter the prostaglandin pattern formed by gastroduodenal mucosa and this may be related to its therapeutic effect.
    Type of Medium: Electronic Resource
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