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  • 1
    Electronic Resource
    Electronic Resource
    A prospective study of the development of hypertension and renal stone disease in subjects with increased blood urate (1983)
    Springer
    Urological research 11 (1983), S. 211-213 
    Details
    ISSN: 1434-0879
    Keywords: Allopurinol ; Blood pressure ; Renal stones ; Hyperuricaemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The results of a prospective study of the development of hypertension and renal stone disease in subjects with increased blood urate are reported and compared with matched controls. None of the 14 patients on Allopurinol developed a renal stone but one untreated control did. For male patients there was a significant difference (p〈0.01) in diastolic blood pressure between the 2 groups over the 5-year study period, with treated patients having higher blood pressures than untreated controls. This suggests that Allopurinol has had no effect on lowering diastolic blood pressure. Long-term therapy with Allopurinol was effective in reducing mean blood urate levels. It is suggested that blood urate levels are more relevant in predicting renal stone formation and of less value in assessing the therapy and prognosis in hypertension.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00272281
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Renal cadmium content in the West of Scotland (1983)
    Springer
    Urological research 11 (1983), S. 285-290 
    Details
    ISSN: 1434-0879
    Keywords: Trace metals ; Cadmium ; Kidney cortex ; Ischaemic heart disease ; Medulla
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The trace element content of kidneys has been documented in very few international centres. Significant differences can be demonstrated between the cortical and medullary levels of calcium, zinc and cadmium. For the West of Scotland the values for the latter are similar to those found in Scandinavia. There are significantly higher cadmium contents in subjects who smoke and who have evidence of ischaemic heart disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256348
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    The effects of treatment on the hypercalciuria of chronic cadmium poisoning (1979)
    Springer
    Urological research 7 (1979), S. 285-289 
    Details
    ISSN: 1434-0879
    Keywords: Cadmium ; Iron ; Bendrofluazide ; Hypercalciuria Hyperzincuria ; Treatment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cadmium induces a variety of effects on kidney tubules including hypercalciuria. This is accompanied by hyperzincuria. The present work shows that both of these biochemical abnormalities can be corrected but where a state of cadmium-induced-anaemia exists urine zinc and calcium excretion do not follow the expected parallel course in response to iron therapy as they do with bendrofluazide.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00256610
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Histological and ultrastructural changes in rat kidney following cadmium injection (1977)
    Springer
    Urological research 5 (1977), S. 15-20 
    Details
    ISSN: 1434-0879
    Keywords: Cadmium ; Kidney ; Ultrastructure
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cadmium injection in rats affects the genito-urinary system. The renal effects are generally considered to be mainly tubular. Light microscopy of 29 specimens confirms cellular damage in the glomeruli with changes in glomerular capillaries. Electron microscopic changes in the glomeruli confirm changes in the podocytes, thickening of the basement lamina, the occurrence of electron dense deposits in association with the capillary endothelium with platelet and polymorphonuclear cell accumulations which suggests opening of the endothelial junction of the glomerular vessels.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00257111
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    Paper (German National Licenses)
    Fulltext
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