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  • 1975-1979  (2)
  • 1970-1974  (3)
  • 1
    Electronic Resource
    Electronic Resource
    Spinal cord tissue cultures-a model for autoradiographic studies on uptake of putative neurotransmitters such as glycine and GABA (1972)
    Springer
    Cellular and molecular life sciences 28 (1972), S. 1342-1344 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Autoradiographische Untersuchungen haben gezeigt, dass3H-Glycin und3H-GABA in kultivierte Neurone und Gliazellen des Rückenmarks der Ratte aufgenommen werden. Aus unseren licht- und elektronenmikroskopischen Befunden geht hervor, dass die Nervengewebskultur ein geeignetes Versuchsmodell für Aufnahme und zelluläre Lokalisation von Überträgersubstanzen ist.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01965334
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Monoamine-containing neurones in cultures of rat brain stem (1971)
    Springer
    Cellular and molecular life sciences 27 (1971), S. 310-311 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Monoaminhaltige Neurone konnten mit Hilfe der Fluoreszenz-Mikroskopie in Hirnstammgewebe, welches während mehrerer Tage in vitro gezüchtet wurde, nachgewiesen werden. Reserpin und Natriumborhydrid bewirkten eine deutliche Abnahme dieser Fluoreszenz. Diese Untersuchungen weisen darauf hin, dass Neurone, welche während mehrerer Tage in vitro gezüchtet wurden, die Fähigkeit haben, Monoamine zu speichern und/oder zu synthetisieren.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02138165
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Effects of potassium on the membrane potential of spinal neurones in tissue culture (1972)
    Springer
    Pflügers Archiv 333 (1972), S. 362-365 
    Details
    ISSN: 1432-2013
    Keywords: Tissue Culture ; Rat Spinal Cord ; Membrane Potentials ; External Potassium
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effects of changes in extracellular potassium concentration on the membrane potential of mammalian spinal neurones in tissue culture have been studied. An increase of extracellular potassium caused a depolarization of the cell membrane which was proportional to the amount of potassium in the bathing fluid. The method of tissue culture provides a useful model for investigating the effects of variations in the extracellular ionic environment on the bioelectric activity of single cells of the mammalian central nervous system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00586215
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Neuron-glia interactions: Indirect effect of GABA on cultured glial cells (1978)
    Springer
    Experimental brain research 33 (1978), S. 425-434 
    Details
    ISSN: 1432-1106
    Keywords: Neuron-glia interactions ; GABA ; Glial cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A study was made of the action of GABA on the membrane potential and resistance of satellite glial (SG) cells in cultures of rat dorsal root ganglia. GABA (10-4M) depolarized all SG cells tested without producing significant changes in membrane resistance. Similar results were obtained from astrocytes of cultured rat spinal cord and brain stem, although only half of the cells tested were depolarized by GABA. Bicuculline (10-5 and 10-6M) which blocked the GABA-depolarization on cultured dorsal root ganglion (DRG) neurons, also markedly reduced or blocked the action of GABA on SG cells. When GABA was tested in sodium-free bathing solution, the amino acid caused a depolarization of similar shape and amplitude as in normal (137 mM Na+) bathing fluid, indicating that uptake processes are probably not involved in producing the depolarization by GABA. It is suggested that the depolarizing action of GABA on glial cells is an indirect effect due to the release of potassium from adjacent neurons during the action of the amino acid.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00235564
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Autoradiographic studies on the uptake of 3H-noradrenaline and 3H-GABA in cultured rat cerebellum (1976)
    Springer
    Experimental brain research 26 (1976), S. 319-324 
    Details
    ISSN: 1432-1106
    Keywords: Uptake ; 3H-GABA ; 3H-Noradrenaline ; Cerebellum ; Tissue Culture
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Autoradiographic studies were made on the uptake of 3H-noradrenaline and 3H-GABA in rat cerebellum grown in tissue culture. GABA was taken up by Purkinje cells and interneurones as well as by glial cells. In contrast, 3H-noradrenaline was only accumulated by nerve fibres but not by neuronal cell bodies and by glial cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00234935
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    Paper (German National Licenses)
    Fulltext
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