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  • 1
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 45 (1973), S. 965-967 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Naturwissenschaften 57 (1970), S. 295-298 
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 224 (1977), S. 437-438 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 224 (1977), S. 434-435 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 212 (1972), S. 397-400 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 20 Frauen mit einem Endometriumcarcinom erhielten nach einer Erstabrasio durchschnittlich 1000 mg 17-Hydroxynorprogesteroncapronia parenteral (Depostat) innerhalb von 14 Tagen. Eine Auszählung der Mitosen nt jeweils 100 Gesichtsfeldern ergab in der Hälfte der Fälle eine niedrigere Mitosezahl um mehr als 50%, davon in 5 Fällen um mehr als 80%. Die durchschnittliche Differenz der Mitosezahl betrug 50% und war damit identisch mit den früheren Resultaten bei Verwendung von 19-Nortestosteronverbindungen. Die differenzierten Carcinome reagierten auf das Gestagen mit einer stärkeren prozentualen Abnahme als die weniger differenzierten Carcinome. — Im Kontrollkollektiv von 25 Endometriumcarcinomen war bei der Zweitabrasio eine geringe Erhöhung der Mitosezahl um 8,3% nachzuweisen. — Eine Gestagenapplikation beim Endometriumcarcinom erscheint vor allem beim progressiven Verlauf, aber auch im Zusammenhang mit der Primärbehandlung prä- und postoperativ begründet.
    Notes: Summary 20 patients with endometrial carcinoma were given an injection of an average dose of 1000 mg 17-hydroxynorprogesteroncapronat (Depostat) within fourteen days after a first abrasion. The number of mitosis was determined by microscopical examination of 100 visual fields of the material obtained by abrasion immediately before and after this treatment. In 50% of the cases the number of mitosis showed a decrease by more than 50%, in 5 cases by more than 80%. The average decrease of the number of mitosis was 50% and therefore identical with earler results obtained by using nortestosterone preparations. The differentiated carcinomas showed a larger decrease than the less differentiated carcinomas.—In the control group of 25 endometrial carcinomas a small increase of the number of mitosis by 8.3% was found in the second abrasion.—A gestagen-application in cases of endometrial carcinoma appears reasonable particularly in the progressive stadium but also in combination with the primary treatment pre- and post-operatively.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 213 (1972), S. 28-30 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 10 Frauen mit einem Endometriumcarcinom wurden insgesamt 40 mg Oestradiolvalerianat zwischen der diagnostischen Erstabrasio und einer Zweitabrasio 14 Tage später injiziert; 10 weitere Frauen nahmen während derselben Zeit täglich 10 mg Diäthylstilboestrolpropionat ein. Die Ergebnisse waren in beiden Kollektiven nahezu identisch. Es ergaben sich somit keine Anhaltspunkte für eine generelle Propagierung proliferativen Wachstums von Endometriumcarcinomen durch hochdosierte Oestrogene. Eine Abhängigkeit vom Differenzierungsgrad des Carcinoms war nicht nachzuweisen.
    Notes: Summary 10 patients with endometrical carcinoma were given an injection of 40 mg estradiolvalerianat within fourteen days between a first diagnostical abrasion and a second abrasion; in the same time 10 other patients took 10 mg diaethylstilbestrolproprionat daily. The results of both groups were nearly identical. Thus no evidence for a general propagation of a proliferative growth of endometrial carcinoma by high doses of estrogens is obtained. A dependence upon the degree of differentiation of the carcinoma was not observed.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 223 (1977), S. 213-220 
    ISSN: 1432-0711
    Keywords: Premenopauseal cycles ; Anovulatory cycle ; Gonadotropine ; Ovarian steriods ; Ovarian insufficiency ; Zyklen in der Prämenopause ; Anovulatorischer Zyklus ; Gonadotropine ; Ovarialsteroide ; Ovarialinsuffizienz
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Aufgrund der kontinuierlichen Bestimmung der Konzentration von FSH, LH, Östradiol-17β und Progesteron im Serum sowie der Gesamt-gonadotropine, der Gesamtöstrogene und des Pregnandiols im 24-Std-Urin konnten 19 Zyklen von Frauen in der Prämenopause zwischen 44 und 50 Jahren in 2 von einander unterscheidbare Gruppen eingeteilt werden. Die erste Gruppe bot die Kriterien des ovulatorischen Zyklus mit verkürzter hyperthermer Phase der Basaltemperatur. Die diskret über der Norm liegenden FSH- und die geringgradig verminderten Östrogen-, Progesteron- und Pregnandiolwerte dokumentierten eine beginnende Insuffizienz der ovulatorischen Ovarialfunktion in der Prämenopause. Die zweite Gruppe war gekennzeichnet durch eine um das Mehrfache erhöhte FSH- und etwas weniger erhöhte LH-Konzentration sowie durch eine stark verminderte Östrogen-, Progesteron- und Pregnandiolkonzentration. Während bei den ovulatorischen Übergangszyklen die Hormonfluktuation noch weitgehend erhalten war, blieb sie später bei konstant anovulatorischer Ovarialfunktion fast vollkommen aus.
    Notes: Summary By serial determinations of plasma LH, FSH, progesterone and estradiol-17β as well as total gonadotropines, total estrogens and pregnanediol in 24 h urine samples it was possible to classify 19 cycles of premenopauseal women, aged 44–50 years, into two groups. The first group showed ovulatory cycles with partially shortened hyperthermic phases in the basal body temperature curves, slightly elevated levels of FSH and diminuished estradiol-17β, pregnanediol and progesterone concentrations, indicating the beginning insufficiency of the ovarian function. The second group was characterized by several times above normal elevated FSH and somewhat less elevated LH levels significantly lowered estradiol-17β and only basal progesterone and pregnanediol concentrations. The ovulatory transitional cycles explicated a nearly normal fluctuation pattern which was completely abolished in the anovulatory cycles.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 224 (1977), S. 399-401 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 224 (1977), S. 22-24 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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