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  • 1970-1974  (3)
  • insulin  (2)
  • Hyperlipoproteinämie Typ III  (1)
  • Acidosis
  • 1
    Electronic Resource
    Electronic Resource
    Interaction between serum calcium concentration and glucose tolerance in normal and azotaemic patients (1973)
    Springer
    Diabetologia 9 (1973), S. 467-471 
    Details
    ISSN: 1432-0428
    Keywords: Calcium ; EDTA ; glucose tolerance ; insulin ; uraemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of calcium infusion on the intravenous glucose tolerance was tested in hypocalcaemic patients suffering from renal insufficiency. It was shown that the delayed glucose disappearance rate in uraemics could be improved (p 〈 0.005) by the infusion of calcium gluconolactobionate despite the fact that the serum concentrations of potassium, urea nitrogen, and the blood pH were not altered. The basal insulin concentration was significantly depressed by the calcium infusion (p 〈 0.02). The serum calcium concentration was significantly correlated to the glucose assimilation coefficient in the uraemic patients (p 〈 0.01). — 3 hypocalcaemic patients without renal failure had a normal glucose tolerance and a normalization of the serum calcium concentration had no discernable effect. — A slight but significant decrease of the serum calcium concentration (p 〈 0.01) by EDTA-Na2 in normocalcaemic patients did not change the intravenous glucose tolerance. — It is concluded that hypocalcaemia may be one of the causes for the abnormal glucose tolerance in chronic renal failure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00461690
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Action of insulin and glucose on the re-esterification rate of free fatty acids in isolated human fat cells (1973)
    Springer
    Diabetologia 9 (1973), S. 499-504 
    Details
    ISSN: 1432-0428
    Keywords: Key words ; Glucose ; fructose ; insulin ; isolated fat cells ; re-esterification of free fatty acids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In isolated human fat cells of the greater omentum and the mammary gland, the effect of glucose, fructose, and/or insulin was tested on the re-esterification rate of FFA measured by the balance method. It could be shown that in the absence of glucose no re-esterification activity was demonstrable. Glucose alone or fructose alone stimulated the re-esterification of FFA dose-dependently in isolated fat cells of the greater omentum, and to a minor degree in fat cells of the mammary gland. Insulin had no effect on the re-esterification rate of FFA in the presence or absence of glucose or fructose, whereas it significantly stimulated the incorporation of glucose-C into CO2 and lipids. It is concluded that the re-esterification of FFA in human adipose tissue, at least in vitro, is mainly controlled by glucose without need for insulin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00461696
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Hyperlipoproteinämie Typ III: Diagnose und quantitative Isolierung des charakteristischen Lipoproteins (1974)
    Springer
    Journal of molecular medicine 52 (1974), S. 792-794 
    Details
    ISSN: 1432-1440
    Keywords: Type III hyperlipoproteinaemia ; rate zonal ultracentrifugation ; Hyperlipoproteinämie Typ III ; zonale Ultrazentrifugation ; linearer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Mit Hilfe einer zonalen Ultrazentrifugationstechnik wurde bei Patienten mit Typ III-Hyperlipoproteinämie ein zusätzliches Lipoprotein (Lp III) quantitativ isoliert. Dieses Lp III ist hinsichtlich seiner hydrierten Dichte (S f 15–20), seines Gehalts an Protein (20%), Gesamtcholesterin (36%) und Triglyceriden (19%), sowie hinsichtlich seiner elektrophoretischen Wanderungsgeschwindigkeit zwischen VLDL (S f 〉20) und LDL (S f 6–8) einzuordnen. Immunologisch konnte wie in den VLDL Apo-Lp B und Apo-Lp C nachgewiesen werden. Lp III wurde bei 50 Normalpersonen und 36 Patienten mit anderen Typen von Hyperlipoproteinämie im Nüchternblut nicht beobachtet. Diese Befunde stützen die Hypothese, wonach bei Typ III-Hyperlipoproteinämie ein Abbaudefekt der triglyceridreichen Lipoproteine vorliegt.
    Notes: Summary In contrast to normals and patients with different types of hyperlipoproteinaemia in 10 patients with type III an intermediate lipoprotein density class (Lp III) was isolated quantitatively. This Lp III showed intermediate characteristics between VLDL and LDL with respect to chemical composition, electrophoretic mobility, and hydrated density. Apo-Lp B and Apo-Lp C were detectable as in VLDL. These findings support the hypothesis of an impaired catabolism of triglyceride-rich lipoproteins in type III patients.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01468740
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    Paper (German National Licenses)
    Fulltext
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