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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Biochimica et Biophysica Acta (BBA)/Protein Structure and Molecular 913 (1987), S. 60-65 
    ISSN: 0167-4838
    Keywords: (E. coli ; Citrate lyase ; Subunit structure
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 355 (1981), S. 628-628 
    ISSN: 1435-2451
    Keywords: Colorectal cancer ; Follow-up ; CEA ; Second-look operation ; Colorectales Carcinom ; Nachsorge ; CEA ; Second Look Operation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Von 1978–1980 wurden 155 Patienten nach potentiell kurativer Operation wegen colorectalen Carcinoms nach einem tumor-spezifischen Nachsorgeprogramm nachuntersucht. Bei 22 von 26 Patienten mit Rezidiv, Fernmetastasen bzw. Zweitcarcinom war der CEA-Test frühester diagnostischer Hinweis, im Mittel 5,5 Monate vor Sicherung der Diagnose. Bei 8 von 10 Second Look Operationen ausschließlich auf Grund des auffälligen CEA-Verlaufes wurden ein Rezidiv bzw. Fernmetastasen intraabdominell gefunden. Bei 16 Patienten erfolgte eine operative Sekundärtherapie, 9mal potentiell kurativ.
    Notes: Summary Between 1978 and 1980 a follow-up study was performed with 155 patients after a curative operation for colorectal cancer. In 26 cases recurrent disease or a second colorectal cancer was diagnosed. In 22 cases the CEA test was the first sign of tumor progression in the mean 5.5 months before clinical diagnosis. In 8 of 10 second-look operations, intraabdominal tumor relapse was found. Of the 16 patients operated on a second time, 9 are potentially curable.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 366 (1985), S. 625-625 
    ISSN: 1435-2451
    Keywords: Colorectal cancer ; Recurrence ; Reoperation ; CEA ; Colorectales Carcinom ; Rezidiv ; Chirurgische Therapie ; CEA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Von 1978–1984 wurden 87 Patienten wegen lokoregionärer Rezidive (35) und metachroner Fernmetastasen (52) colorectaler Carcinome operiert. 28,6% der Patienten mit Rezidiven und 46,2% der Patienten mit Metastasen konnten potentiell kurativ therapiert werden. Zum Zeitpunkt der gesicherten Diagnose hatten 73/87 Patienten einen erhöhten CEA-Wert (≧5 ng/ml). Bei 65/73 Patienten ging der CEA-Ànsbeg der Diagnose voraus. Bei 14 Patienten wurde die Diagnose erst durch eine Second-Look-Operation gesichert. Rezidivpatienten (71,4%) wiesen gegenüber Patienten mit Metastasen (92,3%) seltener erhöhte CEA-Werte auf. Die CEA-Werte der potentielle kurativ operablen Patienten (median 19,7 ng/ml) waren signifikant niedriger (p 〈 0,05) als bei Patienten mit inoperablen Befunden (median 36,9 ng/ml).
    Notes: Summary Between 1978 and 1984, 87 patients with recurrent colorectal cancer have been operated upon. In 10 of 35 patients with locoregional recurrence and 24 of 52 with distant metastases, the therapy was potentially curative. Of 87 patients, 73 had elevated CEA levels (≧ 5 ng/ml) at the time of diagnosis. In 65 of 73 patients, the CEA increase preceded the recognition of recurrence and in 14 patients the diagnosis could be confirmed only by a second-look operation. Patients with metastases (91.3%) showed CEA elevation more often than those with locoregional recurrence (71.4%). Patients with operable disease had significantly (p 〈 0.05) lower CEA values (median 19.7 ng/ml) than those with inperable recurrent carcinomas (median 36.9 ng/ml).
    Type of Medium: Electronic Resource
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