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  • 1
    Electronic Resource
    Electronic Resource
    Einbau von15N-Glyzin in VLDL und LDL: In-vivo-Synthese von Apolipoprotein B beim Menschen postabsorptiv und im Fastenzustand (1989)
    Springer
    Journal of molecular medicine 67 (1989), S. 280-285 
    Details
    ISSN: 1432-1440
    Keywords: 15N-Glycine ; Apolipoprotein-B-Synthesis ; Low density lipoprotein ; Very low density lipoprotein
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In vivo synthesis of apolipoprotein B 100 (ApoB) was recently determined in man using stable isotopes. With this procedure we analyzed (1) the effect of fasting on synthesis of ApoB from very low density lipoprotein (VLDL) and (2) tracer enrichment in low density lipoprotein (LDL). After a 36-hour fasting period and in the post-absorptive state 4 healthy subjects were given a priming dose (8.7 µmol/kg) of15N glycine followed by a constant infusion (10 µmol/kg/h for 8 h) to achieve 5% tracer enrichment in the plasma pool of glycine. The K-values, i.e. fractional synthetic rates/hr of ApoB from VLDL were 0.53±0.26 vs. 0.43±0.16 (p〉0.05). Tracer enrichment in ApoB from LDL at the end of the infusions was 0.19% vs. 1.46% in ApoB from VLDL. The results indicate that (1) in young healthy postabsorptive individuals about 40% of ApoB from VLDL in plasma is synthesized per hour, (2) fasting does not materially affect fractional ApoB synthesis and (3) at 5%15N enrichment in plasma glycine, tracer enrichment in ApoB from LDL is at the lower limit of detection for the procedure employed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01892895
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    355. Zur Wirksamkeit von Fibrinogen und Thrombin bei der Deckung experimenteller Verbrennungswunden (1983)
    Springer
    Langenbeck's archives of surgery 361 (1983), S. 907-907 
    Details
    ISSN: 1435-2451
    Keywords: Burn injuries ; Mesh graft ; Fibrin glue ; Verbrennung ; Mesh-Graft ; Fibrinkleber
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Experimentelle Verbrennungswunden an der Rückenhaut von Ratten (n = 20) im Bereich des thoracolumbalen Übergangs wurden mit Haut-Mesh-graft gedeckt, wobei in der Versuchsgruppe zusätzlich Fibrinkleber (Tissuecol) verwendet wurde. Planimetrische Auswertungen der nach 14 Tagen verbleibenden Wundflächen sowie mikroangiographische, histologische und thermographische Untersuchungen zeigen ein verbessertes Einheilen des Transplantates bei gleichzeitiger Fibrinkleberapplikation, was durch den festen initialen Kontakt zum Wundgrund und die verbesserte Blutstillung erklärt werden kann.
    Notes: Summary Experimental bum injuries in the dorsal thoracolumbar region of rats were covered by skin mesh grafts. In the treated group, fibrin adhesive (Tissucol) was also applied. Fourteen days after transplantation planimetric localization of the remaining wound area, microangiographic, histologic and thermographic studies demonstrated a better healing of the transplant additionally treated with fibrin adhesive. This can be explained by the fibrin-initiated contact with the wound and the hemostyptic effect of the fibrin adhesive.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01276181
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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