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  • Chemistry  (12)
  • OK-432  (2)
  • 33.50.Hv  (1)
  • ACTH  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Neuroendocrine effects of ipsapirone on the hypothalamic-pituitary adrenal axis: CRF, ACTH and cortisol in healthy volunteers (1992)
    Springer
    European journal of clinical pharmacology 42 (1992), S. 163-169 
    Details
    ISSN: 1432-1041
    Keywords: Ipsapirone ; CRF ; ACTH ; cortisol ; time series analysis ; hypothalamic-pituitary-adrenal axis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Medicine
    Notes: Summary The neuroendocrine effects (changes in plasma CRF, ACTH and cortisol) of single and multiple (t.d.s. for 2 days) doses of ipsapirone (BAY Q 7821) 5 and 10 mg have been investigated in 6 healthy male volunteers. The study followed a balanced complete block, placebo-controlled and double blind design with two baseline phases (pre and post-treatment). Volunteers were investigated on identical days during 5 successive weeks. The results do not show a specific effect of ipsapirone on the hypothalamic-pituitary-adrenal axis when doses in the range of 5–30 mg per day were given.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00278478
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  • 2
    Electronic Resource
    Electronic Resource
    OK-432 therapy of lymphangiomas in children (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 649-652 
    Details
    ISSN: 1432-1076
    Keywords: Key words Lymphangioma ; Sklerosing therapy ; OK-432
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Between April 1988 and July 1995, 11 children with a lymphangioma were treated with intralesional OK-432 injection. In 7 patients it was the primary therapy and total shrinkage of the lesion was obtained in 5 of them. Two patients did not respond and the children underwent surgery. Following incomplete surgical removal or recurrence of the lymphangioma, intralesional OK-432 injection was used as secondary therapy in 4 patients. Total regression was observed in 2 cases and marked regression in the 2 others. No serious side-effects except fever lasting for 2–3 days and slight tenderness with swelling of the lymphangioma for 3–4 days after the injection was noted. Local inflammatory reaction did not cause any damage to the overlying skin and did not lead to scar formation. Depending on the size, location, and anatomical relationship to the airway, intralesional injections of the lymphangiomas were performed under general anaesthesia and the children were observed for 24 h. There was no recurrence after follow up periods ranging from 2 months to 7 years. Conclusion Intralesional injection of OK-432 represents an alternative, safe and effective treatment for lymphangiomas. It can be used as the primary therapy, after partial surgical excision, or in recurrent lymphangiomas.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01957145
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  • 3
    Electronic Resource
    Electronic Resource
    OK-432 therapy of lymphangiomas in children (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 649-652 
    Details
    ISSN: 1432-1076
    Keywords: Lymphangioma ; Sklerosing therapy ; OK-432
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Between April 1988 and July 1995, 11 children with a lymphangioma were treated with intralesional OK-432 injection. In 7 patients it was the primary therapy and total shrinkage of the lesion was obtained in 5 of them. Two patients did not respond and the children underwent surgery. Following incomplete surgical removal or recurrence of the lymphangioma, intralesional OK-432 injection was used as secondary therapy in 4 patients. Total regression was observed in 2 cases and marked regression in the 2 others. No serious side-effects except fever lasting for 2–3 days and slight tenderness with swelling of the lymphangioma for 3–4 days after the injection was noted. Local inflammatory reaction did not cause any damage to the overlying skin and did not lead to scar formation. Depending on the size, location, and anatomical relationship to the airway, intralesional injections of the lymphangiomas were performed under general anaesthesia and the children were observed for 24 h. There was no recurrence after follow up periods ranging from 2 months to 7 years.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01957145
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Die Oberflächenspannung geschmolzener Metalle und Legierungen. IV. Die zeitliche Veränderung der Oberflächenspannung und die Methode der Tropfenausmessung bei höherer Temperatur (1933)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 213 (1933), S. 310-318 
    Details
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Die Oberflächenspannung des Quecksilbers im höchsten Vakuum liegt zwischen dem Anfangswert und dem Endwert der Oberflächenspannung in Luft. Bei Zinn konnte eine Veränderung der Oberflächenspannung mit der Zeit im Vakuum von 5·10-5 mm Hg nicht festgestellt werden. Thallium wies eine Zunahme der Oberflächenspannung mit der Zeit im Vakuum von 10-5 bis 10-4 mm Hg auf. Aus diesen Feststellungen wurde geschlossen, daß dort, wo beim Quecksilber Veränderungen der Oberflächenspannung mit der Zeit vorliegen, die sich einstellenden Oberflächenspannungen sich als Resultierende zwischen den Einflüssen der Anordnung der Metallatome der Oberfläche und der ein- und angelagerten Gasatome ergeben.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19332130311
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  • 5
    Electronic Resource
    Electronic Resource
    From torsional spectra to Hamiltonians and dynamics: effects of coupled bright and dark states of 9-(N-carbazolyl)-anthracene (1995)
    Springer
    The European physical journal 34 (1995), S. 111-118 
    Details
    ISSN: 1434-6079
    Keywords: 33.10.-n ; 33.50.Hv ; 33.80.Be
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The torsional dynamics of the 9-(N-carbazolyl)-anthracene (C9A) molecule is investigated by means of time-independent (1) and time-dependent (2) quantum-mechanical simulations in a diabatic representation. The study includes effects of surface crossing of the brightS 1 state with a dark state. (1) The intensity pattern of theS 0 →S 1 fluorescence excitation spectrum is used to fit an effective one-dimensional Hamiltonian with a single-minimum potential for the dark state together with diabatic couplings to the double well potential of the bright state. (2) Based on this Hamiltonian, first predictions for a pump-probe scheme are made. In the pump process the molecules are excited to theS 1 state followed by competing torsions in the bright state and diabatic curve crossings to the dark state, depending on the pump frequency. Assuming the probe process to be an ionization from the bright state, the interfering effects of the dark state on the dynamics in the bright state can be monitored in a directly time-dependent way on a fs-ps time scale.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01439385
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  • 6
    Electronic Resource
    Electronic Resource
    Die Oberflächenspannung geschmolzener Metalle und Legierungen. V. Die Oberflächenspannung von Fe—C-Legierungen, Hg5Tl2NaHg2, ihre zeitliche Veränderung bei Thallium und die Oberflächenspannung von Schlacken (1935)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 223 (1935), S. 84-90 
    Details
    ISSN: 0863-1786
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19352230108
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  • 7
    Electronic Resource
    Electronic Resource
    194. Das Nara-Hybridization-System (1998)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 70 (1998), S. 1205-1206 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.3307009196
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  • 8
    Electronic Resource
    Electronic Resource
    144. Simulation und Optimierung von Kompostierungsanlagen (1996)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 68 (1996), S. 1158-1158 
    Details
    ISSN: 0009-286X
    Keywords: Chemistry ; Industrial Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.3306809146
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  • 9
    Electronic Resource
    Electronic Resource
    Untersuchungen zur Fischer-Tropsch-Synthese in Suspensionsphase an Mn/Fe- und Fe/Cu- KatalysatorenVorgetragen von W.-D. Deckwer auf der Arbeitssitzung des DECHEMA Ausschusses „Technische Reaktionen“ am 11. Februar 1981 in Arnoldshain/Ts. (1981)
    Weinheim : Wiley-Blackwell
    Chemie Ingenieur Technik - CIT 53 (1981), S. 818-819 
    Details
    ISSN: 0009-286X
    Keywords: Fischer-Tropsch-Synthese ; Suspensions-Reaktor ; Mn/Fe- und Fe/Cu-Katalysator ; Produktverteilung nach Schulz-Flory ; Geschwindigkeitskonstanten für Synthesegas-Verbrauch ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Process Engineering, Biotechnology, Nutrition Technology
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/cite.330531016
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  • 10
    Electronic Resource
    Electronic Resource
    Mg2IrB2-x, ein Magnesium-Iridiumborid mit W2CoB2 -verwandter Struktur (1986)
    Weinheim : Wiley-Blackwell
    Zeitschrift für anorganische Chemie 543 (1986), S. 89-96 
    Details
    ISSN: 0044-2313
    Keywords: Chemistry ; Inorganic Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Description / Table of Contents: Mg2IrB2-x, a Magnesium Iridium Boride with a Structure Related to the W2CoB2-TypeThe new compound Mg2IrB2-x with a small homogeneity range determined approximately as 0,2 ≤ x ≤ 0,35 crystallizes monoclinically in the space group C2/m, Z=4 (lattice constants see Inhaltsübersicht). The structure which was solved by single crystal X-ray and powder neutron diffraction methods is related to the W2CoB2-type and contains distorted Mg4Ir2-prisms. The boron atoms are partly disordered. They are situated either inside the prisms forming pairs or with very short Ir-B distances (199 pm) on an elongated prism edge formed by two iridium atoms.
    Notes: Die neue Verbindung Mg2IrB2-x mit einem schmalen Homogenitätsbereich, der näherungsweise zu 0,2 ≤ x ≤ 0,35 bestimmt wurde, kristallisiert monoklin in der Raumgruppe C2/m, Z = 4. Bei x = 0,35 betragen die Gitterkonstanten a = 858,0(1) pm, b = 484,6(1) pm, c = 683,6(1) pm, β = 115°43′(1). Die Struktur, die mit Röntgen-Einkristall- und Pulver-Neutronenbeugungsmethoden bestimmt wurde, leitet sich vom W2CoB2-Typ ab und enthält verzerrte Mg4Ir2-Prismen. Die Boratome sind zum Teil fehlgeordnet. Sie befinden sich entweder innerhalb der Prismen und bilden Paare, oder sie liegen auf einer aufgeweiteten, aus zwei Iridiumatomen bestehenden Prismenkante, wobei sehr kurze Ir-B-Abstände ausgebildet werden (199pm).
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/zaac.19865431211
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