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  • Chemical Engineering  (7)
  • 5-HT autoreceptors  (1)
  • 8-OH-DPAT  (1)
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  • 1
    Digitale Medien
    Digitale Medien
    The 5-HT1A agonist 8-OH-DPAT increases consumption of palatable wet mash and liquid diets in the rat (1988)
    Springer
    Psychopharmacology 94 (1988), S. 58-63 
    Details
    ISSN: 1432-2072
    Schlagwort(e): 8-OH-DPAT ; Feeding ; Drinking ; Palatability ; Appetite ; Fenfluramine ; Satiety ; Rat
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The 5-HT1A agonist 8-OH-DPAT, at a dose of 30 μg/kg, enhanced the consumption of sweetened wet mash and sweetened milk in non-deprived rats. In partially satiated rats, sensitivity to the hyperphagic effect of 8-OH-DPAT on wet mash intake was substantially increased, so that the minimally effective dose was reduced to 3 μg/kg. Similarly, 8-OH-DPAT was more efficacious in increasing milk intake in satiated rats. Thus, 30 and 40 μg/kg 8-OH-DPAT produced a 4-fold increase of milk intake in completely satiated rats compared to a 2-fold increase in partially satiated animals at a dose of 30 μg/kg. The increased intake of liquid and wet mash diets observed after treatment with low doses of 8-OH-DPAT argues against the involvement of non-specific gnawing in the increased consumption of solid food produced by the drug. Rather, the data suggest that 8-OH-DPAT may specifically stimulate appetite by counteracting a tonic serotonergic inhibition of feeding. The present experiments also showed that 8-OH-DPAT attenuates fenfluramine-induced anorexia which is thought to depend on increased serotonergic neurotransmission.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00735881
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  • 2
    Digitale Medien
    Digitale Medien
    Effects of the novel anxiolytics gepirone, buspirone and ipsapirone on free feeding and on feeding induced by 8-OH-DPAT (1987)
    Springer
    Psychopharmacology 93 (1987), S. 349-352 
    Details
    ISSN: 1432-2072
    Schlagwort(e): 5-HT1A receptors ; Anxiolytics ; Interactions ; Feeding ; Rat ; 5-HT autoreceptors
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The effects of the novel anxiolytics gepirone, buspirone and ipsapirone on free feeding and on feeding induced by the 5-HT1A receptor agonist, 8-hydroxy-2-(di-n-propylamino) tetralin (8-OH-DPAT), were examined. Gepirone dose-dependently increased feeding 2 and 4 h after injection, the magnitude of the response being larger than previously observed with any other 5-HT1A receptor ligand. Previous studies have suggested that buspirone and ipsapirone can block some of the behavioural effects of 8-OH-DPAT. However, gepirone, buspirone and ipsapirone did not inhibit feeding induced by 8-OH-DPAT. These results indicate that gepirone is a very efficacious appetite stimulant in rats and suggest that gepirone, buspirone and ipsapirone act as 5-HT autoreceptor agonists in the feeding model.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00187255
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  • 3
    Digitale Medien
    Digitale Medien
    Tensile yield in polyethylenePresented in part at the American Physical Society Meeting in Detroit, Michigan, March 1984 (1986)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 26 (1986), S. 554-559 
    Details
    ISSN: 0032-3888
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: Uniaxial tension tests to the yield point were performed on polyethylene as a function of temperature from 21 to 117°C at a strain rate of 2 min-1. At 21, 45, and 69°C, measurements were also made at strain rates from 0.02 to 8 min-1. Yield energy was found to be a linear function of temperature extrapolating to zero at the melting point (140°C). The ratio of thermal to mechanical energy to produce yielding is about three times smaller than for glassy amorphous polymers. The ratio of yield stress to (initial) Young's modulus is 0.021 at room temperature and increases to 0.059 at 117°C. Also this ratio was found to decrease with log strain rate. For instance, at 21°C for a strain rate of 0.02 min-1 the value was 0.023, while at 8 min-1 this value decreased to 0.020.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pen.760260806
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  • 4
    Digitale Medien
    Digitale Medien
    Tensile yield in polypropylene (1987)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 27 (1987), S. 823-828 
    Details
    ISSN: 0032-3888
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: Untaxial tension tests to the yield point were performed on polypropylene as a function of temperature from 22 to 143°C at a strain rate of 2 min-1. At 22, 42, and 71°C, measurements were also made at strain rates from 0.02 to 8 min-1. Yield energy was found to be a linear function of temperature extrapolating to zero at the melting point (164°C). The ratio of thermal to mechanical energy to produce yielding is about three times smaller than for glassy polymers. The ratio of yield stress to (initial) Young's modulus is about 0.024 at room temperature and increases to 0.043 at 143°C. Yield stress is a linear function of unstrained volume.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pen.760271109
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  • 5
    Digitale Medien
    Digitale Medien
    Simulation of decoking of thermal cracking coils by steam/air-mixtures (1997)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 43 (1997), S. 118-126 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: A rigorous approach was developed for the simulation of the decoking of an industrial cracking furnace. A one-dimensional heterogeneous reactor model, which accounts for the interfacial gradients between the process gas and the coke surface, was used to simulate reactor coils. Both the combustion and steam gasification of the coke layer were taken into account. The reactor model for the decoking was coupled with a detailed firebox simulation model. The initial profile of the coke layer thickness, required for the decoking calculations, was obtained by a run-length simulation. The evolution with time of the temperature distribution inside the cracking coil and in the furnace was generated simultaneously, which made it possible to understand the decoking operation in detail and to predict its duration accurately.
    Zusätzliches Material: 15 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690430114
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  • 6
    Digitale Medien
    Digitale Medien
    Methane steam reforming: II. Diffusional limitations and reactor simulation (1989)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 35 (1989), S. 97-103 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Given the intrinsic kinetics, the tortuosity factor of a Ni/MgAl2O4 catalyst was determined under reaction conditions by minimizing the sum of squares of residuals of the experimental and the simulated conversions. The parallel cross-linked pore model with uncorrelated pore size distribution and orientation was used in the calculation of the effective diffusivities. A modified collocation method was used to obtain the partial pressure profiles of the reacting components in the catalyst pellet. The simulation of the experimental reactor during the optimization of the tortuosity factor also yielded the effectiveness factors of the reactions. The results of the simulation of an industrial steam reformer are also discussed.
    Zusätzliches Material: 7 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690350110
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  • 7
    Digitale Medien
    Digitale Medien
    Methane steam reforming, methanation and water-gas shift: I. Intrinsic kinetics (1989)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 35 (1989), S. 88-96 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Intrinsic rate equations were derived for the steam reforming of methane, accompanied by water-gas shift on a Ni/MgAl2O4 catalyst. A large number of detailed reaction mechanisms were considered. Thermodynamic analysis helped in reducing the number of possible mechanisms. Twenty one sets of three rate equations were retained and subjected to model discrimination and parameter estimation. The parameter estimates in the best model are statistically significant and thermodynamically consistent.
    Zusätzliches Material: 9 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690350109
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  • 8
    Digitale Medien
    Digitale Medien
    Thermal cracking of light hydrocarbons and their mixtures (1977)
    Hoboken, NJ : Wiley-Blackwell
    AIChE Journal 23 (1977), S. 93-106 
    Details
    ISSN: 0001-1541
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: The kinetics and product distributions of the thermal cracking of binary and ternary mixtures of ethane, propane, n- and i-butane were determined in a pilot plant under conditions of residence time, temperature, total pressure, and dilution as close as possible to those prevailing in industrial operation. The kinetics and yields observed with ternary mixtures were compared with those obtained with binary mixtures and with pure components. The experimental selectivities were compared with those which would be obtained from separate cracking and subsequent addition of the product streams. The deviations between the two can be predicted by means of the so-called global kinetics selectivities, which are based upon the selectivities obtained from the pure components cracking and upon the global rates of cracking of the feed components in the mixture.
    Zusätzliches Material: 26 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/aic.690230114
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  • 9
    Digitale Medien
    Digitale Medien
    Tensile yield in poly(chlorotrifluoroethylene) and poly(vinylidene fluoride) (1991)
    Stamford, Conn. [u.a.] : Wiley-Blackwell
    Polymer Engineering and Science 31 (1991), S. 231-238 
    Details
    ISSN: 0032-3888
    Schlagwort(e): Chemistry ; Chemical Engineering
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie , Maschinenbau , Physik
    Notizen: Uniaxial tension tests to the yield point were performed on poly(chlorotrifluoroethylene) (PCTFE) and poly(vinylidene fluoride) (PVF2) from room temperature to near the melting point at a strain rate of 2 min-1. At room temperature and at least two elevated temperatures, measurements were also made at strain rates from 0.02 to 8 min-1. The properties of these polymers were found to be similar to those of other semicrystalline polymers. In the absence of other transitions, yield energy was found to be a linear function of temperature extrapolating to zero near the melting temperature. The ratio of thermal to mechanical energy to produce yielding is smaller than for glassy polymers. Yield stress is a linear function of log strain rate. The ratio of yield stress to (initial) Young's modulus is about 0.03 at room temperature for both polymers. Yield stress is a linear function of unstrained volume. Yield strain, elastic, and plastic strain all initially increase with temperature, but PCTFE shows a decrease with temperature starting at about 100°C, thus behaving like a glassy amorphous polymer in this region.
    Zusätzliches Material: 8 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/pen.760310405
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