Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • Hepatitis B  (2)
  • 65N30  (1)
  • 65Y05 (primary)  (1)
  • 1
    Electronic Resource
    Electronic Resource
    A domain splitting algorithm for parabolic problems (1992)
    Springer
    Computing 49 (1992), S. 11-23 
    Details
    ISSN: 1436-5057
    Keywords: 65M55 ; 65Y05 (primary) ; 65M60 (secondary) ; Domain decomposition ; parallel time stepping ; parabolic problems ; transputer system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Die Implementierung von Lösungs-methoden für parabolische Probleme erfordert eine ausreichende Balance zwischen der parallelen Effizienz voll-expliziter Schemata und der Notwendigkeit von Stabilität und Genauigkeit, welche einen gewissen Grad an Implizitheit bedingt. Als ein Kompromiß wird ein Gebietszerlegungsverfahren vorgeschlagen, welches lokal implizit ist auf leicht überlappenden Teilgebieten, die lokalen Randdaten aber durch einen einfachen expliziten Prozeß fortpflanzt. Die Analyse dieses Algorithmus zeigt, daß er zufriedenstellende Stabilitäts- und Approximationseigenschaften besitzt und effektiv parallelisiert werden kann. Diese theoretischen Resultate werden bestätigt durch numerische Tests auf einem Transputer-System.
    Notes: Abstract In the parallel implementation of solution methods for parabolic problems one has to find a proper balance between the parallel efficiency of a fully explicit scheme and the need for stability and accuracy which requires some degree of implicitness. As a compromise a domain splitting scheme is proposed which is locally implicit on slightly overlapping subdomains but propagates the corresponding boundary data by a simple explicit process. The analysis of this algorithm shows that it has satisfactory stability and approximation properties and can be effectively parallelized. These theoretical results are confirmed by numerical tests on a transputer system.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02238647
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    On finite element methods for elliptic equations on domains with corners (1982)
    Springer
    Computing 28 (1982), S. 53-63 
    Details
    ISSN: 1436-5057
    Keywords: Polygonal domains ; singular expansion ; 65N30
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science
    Description / Table of Contents: Zusammenfassung Es wird eine Finite Elemente Methode zur Approximation elliptischer Differentialgleichungen auf Eckengebieten vorgeschlagen. Das Verfahren benutzt die Singulärfunktionen des Problems im Raum der Ansatzfunktionen und die Kernfunktionen des adjungierten Operators im Testraum. Dadurch erhält man gute Näherungen der Koeffizienten, der Singulärfunktionen. In einem numerischen Beispiel wird das Verfahren mit der bekannten Methode der Singulärfunktionen verglichen.
    Notes: Abstract A finite element method for approximating elliptic equations on domains with corners is proposed. The method makes use of the singular functions of the problem in the trial space and the kernel functions of the adjoint problem in the test space. This leads to good approximates of the coefficients of the singular functions. In the numerical computations, the method is compared with the well known Singular Function Method.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02237995
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Molecular therapeutic strategies in hepatitis B virus infection (1994)
    Springer
    Journal of molecular medicine 72 (1994), S. 737-741 
    Details
    ISSN: 1432-1440
    Keywords: Hepatitis B ; Antiviral agents ; Oligonucleotides ; Antisense
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Chronic infection with the hepatitis B virus is a major health problem worldwide. The only established therapy is interferon-α, with an efficacy of only 30–40% in highly selected patients. Nucleoside analogues do not show a significant clinical benefit. Molecular therapeutic strategies aimed at blocking gene expression include antisense DNA/RNA and ribozymes acting at the posttranscriptional level and triple helix formation blocking at the transcriptional level. In vitro, antisense oligodeoxynucleotides inhibit viral replication and gene expression in human hepatoma cell lines. In vivo, an antisense oligodeoxynucleotide directed against the 5′-region of the pre-S gene of the duck hepatitis B virus inhibited viral replication and gene expression in ducks. In vitro, ribozymes accurately cleave HBV substrate RNA. Triple helix formation is another very promising molecular approach. Results in hepadnaviral infection are not yet available, however.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180539
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 4
    Electronic Resource
    Electronic Resource
    Solid-phase radioimmunoassay for hepatitis be antigen (HBeAg) (1979)
    Springer
    Journal of molecular medicine 57 (1979), S. 1129-1132 
    Details
    ISSN: 1432-1440
    Keywords: Hepatitis B ; HBsAg ; HBeAg ; Anti-HBe ; Solid-Phase Radioimmunoassay ; Hepatitis B ; HBsAg ; HBeAg ; anti-HBe ; Solid-Phase Radioimmunoassay
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary A solid-phase radioimmunoassay was developed for the detection of HBeAg and anti-HBe in sera or serum fractions. HBe/sAg positive sera, partially purified HBeAg, partially purified HBsAg, and HBe/sAg negative sera were polymerized in polyacrylamide and compared for their ability to bind125I-IgG (anti-HBe). Only gels containing HBeAg reacted specifically with the iodinated antibody. The specificity of the binding was confirmed by blocking and inhibition tests using anti-HBe, HBeAg, HBsAg, and negative control sera. The radioimmunoassay allows the specific and quantitative detection of HBeAg and anti-HBe even in the presence of detergents and high salt concentrations.
    Notes: Zusammenfassung Ein Radioimmunoassay wurde entwickelt zum Nachweis von HBeAg und anti-HBe in Serum oder Serumfraktionen. HBe/sAg positives Serum, teilweise gereinigtes HBeAg, teilweise gereinigtes HBsAg und HBe/sAg negatives Kontrollserum wurden in Polyacrylamid polymerisiert und auf ihre Bindungsfähigkeit für125I-IgG (anti-HBe) untersucht. Nur Gele mit immobilisiertem HBeAg reagierten spezifisch mit anti-HBe. Die Spezifität der Bindung wurde gesichert durch Blockierungs-/Inhibitionsteste mit anti-HBe, HBeAg, HBsAg und negativen Kontrollseren. Der Radioimmunoassay ermöglicht den spezifischen und quantitativen Nachweis von HBeAg und anti-HBe, auch in Gegenwart von Detergentien und hohen Salzkonzentrationen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01481494
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...