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  • subarachnoid haemorrhage  (2)
  • 79.60.Bm  (1)
  • Albumin  (1)
  • Cerebral blood flow  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Change in regional cerebral blood flow following glycerol administration predicts (1994)
    Springer
    Acta neurochirurgica 129 (1994), S. 171-176 
    Details
    ISSN: 0942-0940
    Keywords: Cerebral blood flow ; glycerol ; normal pressure hydrocephalus ; shunt surgery ; xenon enhanced computerized tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cerebral haemodynamics were measured in 22 adult patients with secondary normal pressure hydrocephalus (NPH) before and after glycerol administration to determine which patients might benefit from a shunt procedure. Of these 22 patients, 14 were found to be shunt-responsive (group 1) and 8 were shunt-unresponsive (group 2). Measurement of regional cerebral blood flow (rCBF) was performed by xenon-enhanced computerized tomography (XeCT). Clinical factors such as the Evans' index and the presence or absence of brain atrophy, periventricular lucency (PVL), ventricular reflux, stagnation of cerebrospinal fluid on cisternography, and increased intracranial pressure were not statistically significant predictors of shunt responsiveness. Preoperative rCBF values did not differ between groups 1 and 2. The rCBF value in every cerebral region of group 1 patients increased significantly after shunting except for the basal ganglia. On preoperative rCBF measurement, all rCBF values in group 1 significantly increased after glycerol administration except for the periventricular lucency (PVL). Patients in group 2, however, lacked such an increase in rCBF. We therefore propose that, in patients with secondary NPH, shunt surgery will be likely to be effective in those with a demonstrated rise in rCBF after glycerol administration.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01406498
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  • 2
    Electronic Resource
    Electronic Resource
    Atrial natriuretic polypeptide in patients with subarachnoid haemorrhage due to aneurysmal rupture (1989)
    Springer
    Acta neurochirurgica 97 (1989), S. 53-61 
    Details
    ISSN: 0942-0940
    Keywords: Atrial natriuretic polypeptide (ANP) ; hyponatremia ; subarachnoid haemorrhage ; cerebral salt wasting syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Measurement of plasma alpha-humanANP (ANP) and antidiuretic hormone (ADH) in 28 cases with aneurysmal subarachnoid haemorrhage (SAH) was carried out, and then compared with control subjects who were infused with hypertonic saline. In cases with hyponatremia (HN), statistical correlation between control subjects and cases without HN was not evident with regards to ANP and plasma osmolality (Posm), excreted fraction of filtrated sodium (FENa) and urinary Na/K. Furthermore, they secreted supernumerarilly in spite of HN. Cases with HN were further subdivided into two groups, they were those cases with negative total sodium balance at the time of appearance of HN, and those cases without total negative sodium balance. In the former, central venous pressure had a tendency to decrease, however, secretion of ANP and ADH was statistically not different in either groups. It appears that ANP regulated urinary sodium excretion against an osmotic or sodium load acts as a maintenance of homeostasis as an osmotic regulator. Cases with HN in which secretion of ADH was physiological, ANP secreted supernumerarilly in spite of hypoosmonaemia and hypovolaemia. Our findings may contribute to a better understanding of the pathophysiological processes leading to hyponatremia in cases with cerebral disorders, and may help to improve the treatment possibilities.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01577740
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Time course of csf lactate level in subarachnoid haemorrhage correlation with clinical grading and prognosis (1989)
    Springer
    Acta neurochirurgica 99 (1989), S. 127-134 
    Details
    ISSN: 0942-0940
    Keywords: Intracranial aneurysm ; subarachnoid haemorrhage ; cerebrospinal fluid ; lactic acidosis ; cisternal drainage
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Cisternal and/or ventricular cerebrospinal fluid (CSF) and arterial blood lactate and acid-base balance were measured serially in 38 patients with aneurysmal subarachnoid haemorrhage (SAH). Based on daily clinical assessment, the patients and accordingly the samples were divided into two groups according to the grading of the World Federation of Neurosurgical Societies (W.F.N.S.). In cisternal CSF, samples of Grade III–V showed significantly higher lactic acidosis than those of Grade I–II. The time course of lactate and pH in poor prognosis groups had a significant tendency of lactic acidosis, especially on the 5th, 6th, 7th day after SAH. Ventricular CSF lactate increased even without CSF acidosis in Groups III–V. Measurement of CSF lactate, especially from the cisterna magna is useful as an indicator of prognosis and changes of intracranial environment following SAH.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01402321
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Angle-resolved photoemission experiments on Bi2Sr2CaCu2O8+δ(001) (1995)
    Springer
    Applied physics 60 (1995), S. 247-254 
    Details
    ISSN: 1432-0630
    Keywords: 71.25.Hc ; 74.72.Hs ; 79.60.Bm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Abstract Core-level X-ray photoelectron-diffraction patterns have been measured from cleaved Bi2Sr2CaCu2O8+δ (001) surfaces for all elements present in this compound. The incommensurate modulation alongb ([010]) leads to a strong inequivalence ofa- andb-directions for Bi, Sr and Cu photoelectrons, while Ca and O emission show less effect. Ultraviolet-photoemission experiments recording the emission intensity at the Fermi energy over a large solid angle are also presented, providing a direct mapping of the Fermi surface. Ac(2×2) superstructure is observed on the Fermi surface suggesting antiferromagnetic correlations within the Cu−O planes. The effects of the lattice modulation are clearly observable at the Fermi energy, and they are enhanced for binding energies higher than a few tens of meV.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01538399
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  • 5
    Electronic Resource
    Electronic Resource
    Effect of albumin distribution (1989)
    Springer
    Pharmacy world & science 11 (1989), S. 87-91 
    Details
    ISSN: 1573-739X
    Keywords: Albumin ; Clearance ; Distribution ; Midazolam ; Models, theoretical ; Pharmacokinetics ; Protein binding
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The effects of altered albumin distribution on the apparent volume of distribution (V) and the apparent elimination rate constant (k) of drugs were investigated by a simulation analysis. The Equations derived by Øieet al. were modified for this purpose. Within the range observed in normal healthy subjects and patients, the change in albumin distribution significantly affectedV of drugs but, in general, notk. For drugs with more than 90% plasma-protein binding,V changed by more than 100%. The change in plasma-protein binding caused by an altered albumin distribution produced a greater effect onV than that caused by an altered albumin amount. These results suggest that albumin distribution is an important factor in controlling the kinetics of drugs which are highly bound to plasma protein. This is illustrated using midazolam as an example.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02110255
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