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  • Null-Allel  (2)
  • Actualistic approach  (1)
  • Acute mastoiditis  (1)
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    European journal of pediatrics 149 (1990), S. 560-564 
    ISSN: 1432-1076
    Schlagwort(e): Acute mastoiditis ; Subperiosteal abscess ; Central nervous system ; Microbiology ; Treatment
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract The charts of 73 children (31 girls, 42 boys) aged 4 months to 14 years (mean 4.5 years) with acute mastoiditis managed during a 16-year period were reviewed. Of the patients 36% were less than 24 months old. Retro-auricular swelling was described in 63 of the 73 children, tenderness in 59, erythema in 58, and protrusion of the auricle in 45. A pathological tympanic membrane was noted in 33% of the patients and fever in only 29%. Apart from local inflammation, the most frequent complaints and symptoms were otalgia (n=42), recent upper respiratory tract infections (n=22), and fever alone (n=22). A subperiosteal abscess was found in 36 patients, and CNS involvement in 5. Nearly half of the patients (48%) were on antibiotic therapy at admission. The isolation rates in bacterial cultures from subperiosteal aspirates (81%) and from mastoid mucosa (68%) were considerably higher than from blood cultures (14%) and were not influenced by previously administered antibiotics. Pneumococci (9/32) andStaphylococcus epidermidis (6/32) were the agents most often isolated. The incidence of the bacteria isolated from patients pre-treated with antibiotics differed from the incidence in patients not previously treated. In 24 patients (33%) the lesion healed with antibiotic therapy without mastoid surgery. Myringotomy and the insertion of a ventilation tube is indicated initially, if acute otitis media with effusion is found. In the absence of a subperiosteal abscess and of CNS involvement, a 48-hour trial of intravenous antibiotic therapy, directed also against staphylococci, is justified before mastoid surgery is considered.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    International journal of legal medicine 103 (1990), S. 609-612 
    ISSN: 1437-1596
    Schlagwort(e): PGM-phenotypes ; Enzyme-activity ; Silent allel ; PGM-Phänotypen ; Enzym-Aktivität ; Null-Allel
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Rechtswissenschaft
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Die Enzymaktivität der erythrozytären Phosphogluco-mutase wurde in 142 Hämolysaten bestimmt. Die PGM-Phänotypen wurden mittels Isoelektrofokussierung auf Polyacrylamid-Gel ermittelt. Dabei konn-ten 10 verschiedene Phänotypen dargestellt werden. Die mittlere Enzymakti-vität dieser 10 Phänotypen weist signifikante Unterschiede auf. Ein stummes Allel bzw. ein Allel mit reduzierter PGM-Aktivität wurde nicht festgestellt. Es zeigte sich eine Korrelataion zwischen Enzymaktivität und isoelektrischem Punkt der vier Homozygoten.
    Notizen: Summary The enzyme activity of phosphoglucomutase (PGM) has been investigated in red cell haemolysates from 142 individuals and compared to the sub-type as determined by isoelectric focusing. The 10 phenotypes showed significant differences in PGM-activity which indicates that there is a correlation between the level of activity and the isolelectric point of homozygotes. No indication of silent alleles or alleles with reduced activity was found in this collective.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Digitale Medien
    Digitale Medien
    Springer
    International journal of legal medicine 103 (1990), S. 609-612 
    ISSN: 1437-1596
    Schlagwort(e): PGM-phenotypes ; Enzyme-activity ; Silent allel ; PGM-Phanotypen ; Enzym-Aktivität ; Null-Allel
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin , Rechtswissenschaft
    Beschreibung / Inhaltsverzeichnis: Zusammenfassung Die Enzymaktivität der erythrozytdren Phosphoglucomutase wurde in 142 Hdmolysaten bestimmt. Die PGM-Phänotypen wurden mittels Isoelektrofokussierung auf Polyacrylamid-Gel ermittelt. Dabei konnten 10 verschiedene Phanotypen dargestellt werden. Die mittlere Enzymaktivität dieser 10 Phänotypen weist signifikante Unterschiede auf. Ein stummes Allel bzw. ein Allel mit reduzierter PGM-Aktivität wurde nicht festgestellt. Es zeigte sich eine Korrelataion zwischen Enzymaktivitat und isoelektrischem Punkt der vier Homozygoten.
    Notizen: Summary The enzyme activity of phosphoglucomutase (PGM) has been investigated in red cell haemolysates from 142 individuals and compared to the sub-type as determined by isoelectric focusing. The 10 phenotypes showed significant differences in PGM-activity which indicates that there is a correlation between the level of activity and the isolelectric point of homozygotes. No indication of silent alleles or alleles with reduced activity was found in this collective.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 4
    ISSN: 1437-3262
    Schlagwort(e): Micropalaeontology Palaeo-oceanography ; Plankton ; Sediment traps Recent and Holocene sediments ; Actualistic approach ; Norwegian-Greenland Sea
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Geologie und Paläontologie
    Notizen: Abstract A synoptic study is carried out to reconstruct the development of the plankton community in the late Quaternary in the Norwegian-Greenland Sea. It comprises quantitative analyses of coccolithophores, dinoflagellate cysts, diatoms and radiolarians. An actualistic approach is applied to evaluate the different fossil records of these plankton groups. The preliminary results of the current investigation are reported here. The composition and distribution of living communities of coccolithophores are presented as an example. A close relationship between the distribution of regional groups and surface water masses is observed. Seasonal vertical fluxes of coccolithophores and radiolarians through the water column show similar patterns within different years. However, diatoms are highly variable, both in absolute fluxes and species composition. The differentiation of sporadic and periodic processes is evident only after several years of observation. During settling and sedimentation biotic and abiotic processes such as grazing, dissolution and lateral transport alter the assemblages. Investigation of death assemblages in surface sediments reveals that in spite of these alteration processes the abundance and species distribution are related to surface water masses. Higher abundances and diversities are usually found in sediments underlying the warm Norwegian Current. Concentrations decrease to the north-west towards the cold polar water masses. The sediment assemblages of all groups are strongly altered relicts of former living communities. They are characterized by distinct changes in species composition and absolute abundances related to palaeo-oceanographic development. Their variation through the sedimentary record is used to distinguish four ecostratigraphic units during the late Weichselian and Holocene.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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