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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 129 (1978), S. 67-72 
    ISSN: 1432-1076
    Keywords: Allergy ; Capillary resistance ; Corticosteroids ; Hemorrhagometry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Fifty four of 67 allergic children (81%) had a pathologically reduced capillary resistance (CR) of less than 16 cm Hg. Five of the 13 allergic children with normal CR were treated with corticosteroids. Prednisone improved CR in one patient for at least 24 h, and this was reflected by improvement of hemorrhagic parameters such as bleeding intensity, bleeding pattern and blood loss. There was no correlation between CR and IgE levels. 90% of the symptomatic relatives of allergic children had a reduced CR, but only 44% of asymptomatic relatives. CR presents a simple additional tool for diagnosing allergy and might give hints to the carrier state of allergy.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1440
    Keywords: Bienengift-spezifisches IgG ; Subklassen IgG 1–4 Antikörper ; Allergie ; Schutz bei Imkern ; Bee venom specific IgG ; Subclass IgG 1–4 antibodies ; Allergy ; Protective effect in bee-keepers
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Specific IgE antibodies against bee venom and its components were studied in 23 bee-keepers. The highest IgG serum levels were observed for whole bee venom followed by phospholipase A. The serum levels of specific IgG antibodies against melittin and MCD-peptide were lower, the lowest serum levels being observed for apamin. After a 5 month absence from bee-keeping a fall in the serum levels of IgG antibodies was observed in all the bee-keepers studied. The investigation of the IgG subclass antibodies 1–4 against bee venom and phospholipase A demonstrated the highest serum levels for IgG 4 and IgG 2, the lowest levels were observed for IgG 1. The lowest IgG serum levels were associated with the least effective protection to bee stings. These findings support the concept that specific IgG antibodies prevent the development of allergic symptoms after bee sting.
    Notes: Zusammenfassung Spezifische IgG-Antikörper gegen Bienengift und Bienengift-Bestandteile wurden im Serum von 23 Imkern bestimmt. Die höchsten Titer wurden gegen das Gesamt-Bienengift gefunden, jeweils geringere gegen Phospholipase A, Melittin, MCD-Peptid und Apamin. Bei Messung der spezifischen IgG-Antikörper der Subklassen 1–4 gegen Gesamt-Bienengift und Phospholipase A wurden die höchsten Titer in den Subklassen 4 und 2, die niedrigsten in der Subklasse 1 gefunden. Nach 5 Monaten ohne Bienenstiche wiesen alle untersuchten Imker einen Antikörper-Abfall auf. Die klinisch stärkste Reaktion auf Bienenstiche zeigten Imker mit den niedrigsten spezifischen IgG-Spiegeln. Diese Untersuchungen zeigen, daß spezifische IgG-Antikörper eine wichtige Rolle bei der Verhinderung von allergischen Symptomen nach Bienenstich spielen.
    Type of Medium: Electronic Resource
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