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  • Chromatophores  (3)
  • Light-sensitivity  (3)
  • MRT  (3)
  • Analytical Chemistry and Spectroscopy  (2)
  • Cancer patients  (2)
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  • 1
    Electronic Resource
    Electronic Resource
    Bildgebende Diagnostik der Virusenzephalitiden (2000)
    Springer
    Der Radiologe 40 (2000), S. 998-1010 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Virale Enzephalitis ; MRT ; Herpes-simplex-Virus ; HIV ; Keywords Virus encephalitis ; MRI ; Herpes simplex virus ; HIV
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The diagnostic procedure in viral encephalitis is based on the synopsis of clinical signs and symptoms, serological data, CSF analysis and diagnostic imaging findings. This article summarizes the findings of those viral encephalitides most frequently encountered in Western Europe. MRI is more sensitive than CT for the detection of inflammatory brain lesions due to the higher contrast resolution. The pattern of parenchymal damage is highly specific in only some viral encephalitides (e. g., the frequently hemorrhagic lesions of structures of the limbic system in herpes simplex virus type I encephalitis; the symmetric and confluent lesions of the frontal white matter of progressive diffuse leukoencephalopathy in AIDS). In the majority of viral encephalitides MRI demonstrates the location and extension of parenchymal damage. The specific diagnosis in terms of the causative agent is based on serological studies.
    Notes: Zusammenfassung Die Diagnostik viraler Enzephalitiden basiert auf der synoptischen Auswertung klinischer, serologischer, liquoranalytischer und bildgebend erhobener Befunde. In der vorliegenden Arbeit werden die entsprechenden Befunde der häufigsten in Westeuropa viral verursachten Enzephalitiden dargestellt. Generell ist bei entzündlichen Läsionen des Hirnparenchyms die Kernspintomographie (MRT) aufgrund ihrer hohen Weichteilkontrastauflösung der Computertomographie (CT) hinsichtlich der Nachweissensitivität überlegen. Bei einigen viralen Enzephalitiden ist das kernspintomographisch erfassbare Schädigungsmuster hochspezifisch. Die gilt z. B. für die häufig hämorrhagischen Läsionen der Strukturen des limbischen Systems bei der Herpes-simplex-Virus-Typ-1-Enzephalitis und für die flächenhaft symmetrischen Marklagerläsionen bei der progressiven diffusen Leukenzephalopathie bei AIDS-Patienten. Bei der Mehrzahl der viralen Enzephalitiden weist die MRT zwar die Lokalisation und Ausdehnung der Parenchymschädigung nach, erlaubt jedoch keine sichere Zuordnung zu einem Erreger.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050872
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  • 2
    Electronic Resource
    Electronic Resource
    Klinik und bildgebende Diagnostik der Sarkoidose des Nervensystems (2000)
    Springer
    Der Radiologe 40 (2000), S. 1064-1076 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Sarkoidose ; Neurosarkoidose ; Granulom ; MRT ; Keywords Sarcoidosis ; Sarcoidosis complications ; Neurosarcoidosis ; Granuloma ; Brain diseases complications ; Magnetic resonance imaging
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The central nervous system is frequently affected during the course of sarcoidosis. Many of these lesions remain without clinical correlates. Unenhanced and contrast enhanced CT and MRI play an important role during the diagnostic work-up of patients with sarcoidosis and suspected or proved CNS involvement. This article summarizes the most frequent manifestations of neurosarcoidosis and provides illustrative examples of MRI findings.
    Notes: Zusammenfassung Das Nervensystem ist bei der Sarkoidose häufiger mitbeteiligt als nach klinischen Gesichtspunkten zu vermuten wäre. Den bildgebenden Untersuchungsverfahren kommt eine große Bedeutung beim Nachweis der pathologischen Veränderungen zu. Insbesondere die Kernspintomographie sichert die Diagnosestellung und dient der Verlaufsbeurteilung. In dieser Übersichtsarbeit werden die typischen klinischen und bildgebenden Befunde bei der Neurosarkoidose vorgestellt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050879
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  • 3
    Electronic Resource
    Electronic Resource
    Tuberculin and dinitrochlorobenzene (DNCB) tests in cancer patients before and after cytostatic drug therapy (1978)
    Springer
    Journal of molecular medicine 56 (1978), S. 905-909 
    Details
    ISSN: 1432-1440
    Keywords: Tuberkulin-Test, Dinitrochlorbenzoltest ; Zytostatische Therapie ; Solide Karzinome ; Zelluläre Immunität ; Tuberculin test ; DNCB test ; Cytostatic drug therapy ; Cancer patients
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary In 137 patients with different kinds of cancer and different cancer stage, cell-mediated immunity was investigated by DNCB (dinitrochlorobenzene) and tuberculin test. These two skin tests were performed before and after cytostatic drug combination therapy. For a collective of cancer patients we found a positive correlation between skin reactions and prognosis and a negative correlation between skin reactions and cancer stage. After cytostatic drug therapy skin reactions could be significantly stronger. This could be observed in 50% when one test was positive before chemotherapy and in only 20% when both tests were negative before chemotherapy. There existed a significant correlation between an increased reaction after cytostatic drug therapy and objective tumor regression. When skin reactions decreased, tumor progression was seen in all cases. Due to these observations we use skin reactions as a good parameter for therapy results. When delayed cutaneous hypersensitivity impairs 2–3 weeks after chemotherapy, we then change the cytostatic drug combination immediately. We cannot say at this moment, whether an improvement of cytostatic drug therapy can be reached in this way.
    Notes: Zusammenfassung Bei 137 Patienten mit unterschiedlichen soliden Karzinomen und verschiedenem Tumorstadium wurde die zelluläre Immunität durch Tuberkulin- und DNCB-(Dinitrochlorbenzol)-Test untersucht. Die Tests wurden vor und nach zytostatischer Stoßtherapie durchgeführt. Insgesamt fanden wir eine positive Korrelation zwischen Hauttests und Prognose und eine negative Korrelation zwischen Hauttests und Tumorstadium. Wenn mindestens ein Test vor Chemotherapie positiv war, konnten wir in ca. 50% eine Verbesserung der zellulären Immunität registrieren, dagegen nur in 20%, wenn beide Tests vor zytostatischer Therapie negativ waren. Ein signifikanter Zusammenhang zwischen verbesserter Reaktion auf Tuberkulin und/oder DNCB nach zytostatischer Therapie und objektiver Tumorrückbildung wurde beobachtet. Wenn beide Reaktionen schwächer wurden, folgteimmer eine Tumorprogression. Aufgrund dieser Beobachtungen verwenden wir die Hauttests als wertvollen Parameter für den Therapieerfolg. Wir wechseln daher sofort die Zytostatikakombination, wenn 2–3 Wochen nach Chemotherapie die Hautreaktionen schwächer werden. Ob hierdurch eine Verbesserung der Zytostatikatherapie möglich ist, kann derzeit noch nicht sicher gesagt werden.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01489216
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  • 4
    Electronic Resource
    Electronic Resource
    Septisch-embolischer und septisch-metastatischer Hirnabszess (2000)
    Springer
    Der Radiologe 40 (2000), S. 1017-1029 
    Details
    ISSN: 1432-2102
    Keywords: Schlüsselwörter Hirnabszess ; Zerebritis ; Metastatische Herdenzephalitis ; Endokarditis ; MRT ; Gd-DTPA ; Keywords Brain abscess ; Cerebritis ; Metastatic focal encephalitis ; Endocarditis ; MRI ; Gd-DTPA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract The hematogenous spread of bacteria, fungi and protozoa may also reach the brain vessels, which happens mostly through septic emboli. From such an embolus a metastatic focal encephalitis and later a septic-embolic brain abscess may arise. The most frequently underlying infections that may cause septic emboli are bacterial endocarditis as well as bacterial infections of artificial heart valve prostheses. Congenital heart malformations with a right-to-left shunt also play here a certain role. Basically, however, all septic conditions and bacteriemias may cause septic-embolic brain abscesses. They occur frequently as multiple lesions. MRI is superior to CT in depicting the different stages of evolution from focal encephalitis, through the hardly encapsulated early abscess, to the formation of a membrane and later a dense fibrous capsule. The medical treatment of a brain abscess requires properly performed CT or MRI follow-up examinations in order to realize early enough a possible growing of such a lesion.
    Notes: Zusammenfassung Die hämatogene Ausbreitung von Bakterien, Pilzen oder Protozoen bis in die Hirngefäße erfolgt meist durch eine septische Embolie. Es entstehen eine metastatische Herdenzephalitis und im weiteren Verlauf daraus ein septisch-embolischer Hirnabszess. Die häufigste Grunderkrankung die zu septischen Embolien führt ist die bakterielle Endokarditis sowie die bakterielle Infektion von Herzklappenprothesen. Eine besondere Bedeutung kommt hier den angeborenen kardialen Fehlbildungen mit Rechts-Links-Shunt zu. Grundsätzlich können jedoch alle Bakteriämien zu septisch-embolischen Hirnabszessen führen. Septisch-embolische Hirnabszesse treten aufgrund ihres Entstehungsmechanismus häufig multipel auf. Die CT und besser noch die MRT erlauben die Darstellung aller Entwicklungsstadien von der Herdenzephalitis über den kaum abgegrenzten Abszess, die Membranbildung bis zur Entstehung einer dicken, die eitergefüllte Höhle allseits umgebenden Abszesskapsel. Die medikamentöse Therapie von Hirnabszessen erfordert Verlaufsuntersuchungen, um einer eventuellen Größenzunahme der Läsion(en) frühzeitig durch Umstellung der antibiotischen Medikation oder durch operative Abszessentfernung zu begegnen.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001170050874
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  • 5
    Electronic Resource
    Electronic Resource
    Oncology Home Care Service (1998)
    Springer
    Supportive care in cancer 6 (1998), S. 195-196 
    Details
    ISSN: 1433-7339
    Keywords: Key words Oncology nursing ; Cancer patients ; Palliative care
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The Oncology Home Care Service in Basel provides nursing support to let cancer sufferers choose where they receive palliative care. Most of the cost is borne by the patient's health insurance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s005200050153
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  • 6
    Electronic Resource
    Electronic Resource
    Amöboid bewegliche Pigmentzellen im Epithel des Seeigels Centrostephanus longispinus (1972)
    Springer
    Cell & tissue research 133 (1972), S. 82-102 
    Details
    ISSN: 1432-0878
    Keywords: Echinoidea ; Colour change ; Chromatophores ; Amoeboid movement ; Electron microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Description / Table of Contents: Zusammenfassung Für den physiologischen Farbwechsel bei Vertebraten und Evertebraten gilt die Vorstellung, daß eine Pigmentbewegung innerhalb einer formkonstanten Zelle stattfindet. Am Seeigel Centrostephanus longispinus wird nun der Nachweis einer amoeboiden Bewegung von Pigmentzellen geführt: Die Epidermis von Centrostephanus enthält große braune Chromatophoren, die bei Belichtung eine Pigmentdispersion, bei Verdunkelung eine Konzentration des Pigments zeigen. Die Chromatophoren sind außerordentlich stark verzweigte Zellen, deren Arme dicht mit Pigmentgrana erfüllt sind. Im geballten Zustand ist die allgemeine Zellform mehr oder weniger ovoid, wobei die Zellarme eingezogen und dicht um die Zellmitte angeordnet sind. Dispersion des Pigments wird hervorgerufen durch Ausstrecken der pigmentierten Zellarme in den Interzellularraum des umgebenden Gewebes. Innerhalb der Zelle werden filamentöse Elemente nachgewiesen, die vermutlich für die Zellbeweglichkeit verantwortlich sind. — Ferner wird der zelluläre Aufbau des Integuments beschrieben.
    Notes: Summary Rapid colour changes in vertebrate and invertebrate species are considered to be due to movement of pigment granules within pigment cells of constant shape. Evidence is presented in this study to show that an amoeboid movement of chromatophores occurs in the epidermis of the Echinoderm Centrostephanus longispinus. The epidermis in this species contains large brown chromatophores, which display a dispersion of pigment on illumination and its concentration on darkening. The chromatophores are extensively branched cells, and their branches are densely packed with pigment granules. In the state of pigment concentration, the shape of the cell is more or less ovoid, and the cell branches are drawn in and closely arranged around the cell centre. Dispersion is attained by a stretching out of the pigmented cell branches into the intercellular spaces of the surrounding tissue. Within the cell, filamentous elements, which may be functional in the motility of the pigment cell, can be demonstrated.—Additionally the cellular composition of the integument is described.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00307069
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  • 7
    Electronic Resource
    Electronic Resource
    Light-sensitivity of isolated pigment cells of the sea urchin Centrostephanus longispinus (1974)
    Springer
    Cell & tissue research 148 (1974), S. 437-440 
    Details
    ISSN: 1432-0878
    Keywords: Amoeboid pigment cell ; Colour change ; Echinoidea ; Light-sensitivity ; Interference contrast microscopy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Pigment cells isolated from the epithelium of the sea urchin Centrostephanus longispinus display light-sensitivity in the same manner as in normal tissue. In complete darkness they have a round to ovoid shape. On illumination a successive extension of pigment-bearing processes can be observed. Darkness leads to a successive retraction of the pseudopodia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00224270
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  • 8
    Electronic Resource
    Electronic Resource
    Light-induced alterations in cell shape and pigment displacement in chromatophores of the sea urchin Centrostephanus longispinus (1977)
    Springer
    Cell & tissue research 182 (1977), S. 165-176 
    Details
    ISSN: 1432-0878
    Keywords: Chromatophores ; Light-sensitivity ; Granule motion ; Echinoids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Alterations in cell shape of the light-sensitive chromatophores of Centrostephanus longispinus are described. Upon illumination a centrifugal pigment movement starts within extremely thin filopodia which radiate from the cell body. With continued pigment migration the cellular processes increase in length and diameter and give the cell an irregular stellate appearance. Pigment movement within the cellular processes is discontinuous in space and time and may occur independently in single filopodia. The motion of single granules shows characteristic features of a saltatory movement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220586
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  • 9
    Electronic Resource
    Electronic Resource
    Ultrastructural observations on changes in cell shape in chromatophores of the sea urchin Centrostephanus longispinus (1980)
    Springer
    Cell & tissue research 206 (1980), S. 21-33 
    Details
    ISSN: 1432-0878
    Keywords: Chromatophores ; Light-sensitivity ; Alteration in cell shape ; Microtubules ; Echinoids
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Alterations in cell shape of the light-sensitive chromatophores of the sea urchin Centrostephanus longispinus were studied by scanning- and transmission electron microscopy. Transition of the aggregated to the dispersed state is accompanied by incorporation of vesicles into the membrane of the pigment cell. During dispersion a system of microtubules originating from centriole-like structures is established throughout the stellate cell. Within restricted areas of the cell, cytoplasmic differentiation and condensation is found. The possible functional significance of the findings is briefly discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00233604
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  • 10
    Electronic Resource
    Electronic Resource
    Raman investigation of simple and complex oxides of platinum (1991)
    Chichester [u.a.] : Wiley-Blackwell
    Journal of Raman Spectroscopy 22 (1991), S. 1-9 
    Details
    ISSN: 0377-0486
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology , Physics
    Notes: Raman spectra were obtained from PtO, Pt5O6, Pt3O4, α-PtO2, β-PtO2, MxNayPt3O4 (M = Co, Ni), PtCoO2 and MPt3O6 (M = Mn, Co, Cd). An enumeration of the allowed Raman modes is made for all of these oxides except Pt5O6, for which the structure is unknown. Polarization measurements allow symmetry species assignments to be made for the lines from α-PtO2 and PtCoO2, and a likely assignment of the lines from β-PtO2 is made by analogy with rutile-structured materials with the rutile structure.
    Additional Material: 15 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/jrs.1250220102
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