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  • 1
    Electronic Resource
    Electronic Resource
    Relationship between the degree of injury at operation and the change in antimyosin antibody titer in the postpericardiotomy syndrome (1994)
    Springer
    Pediatric cardiology 15 (1994), S. 116-120 
    Details
    ISSN: 1432-1971
    Keywords: Antimyosin antibody titer ; Cardiac myosin light chain I ; Creatine kinase isoenzyme MB ; Postpericardiotomy syndrome
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Successive measurements of cardiac myosin light chain I (MLC), creatine kinase isoenzyme MB (CKMB), and the titer of antimyosin antibody (AMA) were performed prospectively in 19 patients following open heart surgery. Seven of these patients showed the postpericardiotomy syndrome (PPS). No differences in serum concentrations of MLC or CKMB were observed between the patients with and without PPS, and all patients in both groups had abnormal MLC values after surgery. However, only patients with PPS had significantly elevated AMA titers. The maximum AMA titer was significantly correlated with the severity of the effusion. These data suggest that PPS is unrelated to the severity of myocardial injury during operation. Furthermore, the AMA titer may be useful as one of the indicators for determining the patient's clinical condition.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00796322
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Mitral regurgitation may be related with previous streptococcal infection (1996)
    Springer
    European journal of pediatrics 155 (1996), S. 168-172 
    Details
    ISSN: 1432-1076
    Keywords: M protein ; Antibody ; Children ; Streptococcal infection ; Mitral regurgitation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We measured anti M protein antibody (AMPA) titres in children with idiopathic mitral regurgitation (MR), streptococcal infection, rheumatic fever (RF), post-streptococcal acute glomerulonephritis (AGN) and normal healthy children. We investigated the association of MR with streptococcal infection and whether high AMPA titres can be used as persisting evidence of previous streptococcal infection. AMPA titres were measured with an enzyme-linked immunosorbent assay. We found significantly higher antibody titres in patients with MR and in streptococcal infection, RF, and AGN than in healthy controls. In the MR group (n=15), 54% patients had AMPA titres above the 90th percentile value that was found in normal controls. An elevated AMPA titre persisted for a long period even when the anti-streptolysin O titres had declined to normal in RF patients. Our data suggest that the high AMPA titres in MR should be further investigated to clarify the probable association with previous streptococcal infection. Conclusion High AMPA titre is a risk factor for developing complications after streptococcal infection. Our serological evidence suggests that in some patients. MR may be related to previous streptococcal infection.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01953931
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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