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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 262 (1978), S. 7-14 
    ISSN: 1432-069X
    Keywords: Black skin ; Actinic elastosis ; Light- and electronmicroscopy ; Fibroblastic product ; Negerhaut ; Aktinische Elastose ; Licht- und Elektronenmikroskopie ; Fibroblastenprodukt
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei 9 hautgesunden südafrikanischen schwarzen Freiwilligen im Alter von 1–72 Jahren wurde sonnenlichtexponierte und nichtexponierte Haut licht- und elektronenmikroskopisch untersucht unter besonderer Berücksichtigung altersabhängiger und aktinisch bedingter Veränderungen dermaler Strukturen. Während bei einer 72jährigen Frau eine ausgeprägte aktinische Elastose im oberen Corium der sonnenexponierten Haut licht- und elektronenoptisch nachweisbar war, fand sich bei einem 72jährigen Mann eine nur elektronenoptisch darstellbare geringe Elastose. Im Gegensatz dazu waren bei diesen beiden Fällen im unteren Corium der sonnenexponierten und in allen Schichten der nichtexponierten Haut nur altersentsprechende elastische Fasern vorhanden. Diese Beobachtungen stehen in Gegensatz zu der noch gängigen Auffassung, daß eine aktinische Elastose bei der kongoiden Rasse nicht auftritt. Das elastotische Material ist offensichtlich ein de-novo-synthetisiertes und sezerniertes pathologisches Produkt von (durch chronische UV-Bestrahlung) alterierten Fibroblasten.
    Notes: Summary In 9 otherwise dermatologically normal South African Black volunteers (1–72 years old), sunlight-exposed and non-exposed skin has been examined by light- and electronmicroscopy with special references to age-dependent and actinic alteration of dermal structures. Two 72 year old Blacks exhibited typical dermal elastosis: in 1 case to a marked extent and already detectable by lightmicroscopy, in the other case only to a mild degree. In contrast, only age-related elastic fibers were revealed in the lower dermis of sunlight-exposed skin and in all dermal layers of unexposed skin. These observations are contradictory to the general view that actinic elastosis does not occur in Blacks. The elastotic material is obviously a de-novo synthesized and secreted pathological product of chronically UV-altered fibroblasts.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 153 (1994), S. 409-410 
    ISSN: 1432-1076
    Keywords: Children ; Diabetes Insulin ; Jet injection ; Pain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The aim of this study was to investigate whether insulin application by jet injector is less painful than by needle. Pain was scored by 41 diabetic and seven healthy volunteers after injections with both methods. Injections by jet were no less painful than those by needle but produced several local side-effects.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 157 (1998), S. 802-805 
    ISSN: 1432-1076
    Keywords: Key words Insulin-dependent diabetes mellitus ; Cognitive function ; Attention ; Blood glucose level ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We compared the results of a computerized attention test (TOVA) in 38 children with insulin dependent diabetes mellitus in relation to various spontaneously occurring blood glucose levels. Testing was performed at the following blood glucose levels: 〈3.3 mmol/l (hypoglycaemia), 3.3–8.3 mmol/l (normoglycaemia) and 〉8.3 mmol/l (hyperglycaemia) . The attention (sum of errors and response time) varied significantly with the blood glucose level (P=0.002). The highest number of errors of omission and the longest response time was observed during the test run with hypoglycaemia. Age, sex, age at manifestation of the disease, metabolic control and the results of the intelligence test had no significant influence on these results. We found that attention in children with diabetes was significantly reduced compared to TOVA norms especially during mild hypoglycaemia (P〈0.001). Irrespective of the blood glucose levels, reaction time and the variability of the reaction time differed significantly between TOVA norms and diabetic children (P〈0.01). Conclusion In children with diabetes mellitus a significant reduction in attention was found at mild hypoglycaemia but as well at low normal blood glucose levels. Attention deficits due to transient lowering of blood glucose may therefore occur in diabetic children even before they are aware of hypoglycaemic symptoms.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 153 (1994), S. 409-410 
    ISSN: 1432-1076
    Keywords: Key words     Children ; Diabetes ; Insulin ; Jet injection ; Pain
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract      The aim of this study was to investigate whether insulin application by jet injector is less painful than by needle. Pain was scored by 41 diabetic and seven healthy volunteers after injections with both methods. Injections by jet were no less painful than those by needle but produced several local side-effects.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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