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  • Brain tumour  (1)
  • Facial reconstruction  (1)
  • First order canal neuron dynamics  (1)
  • 1
    ISSN: 1437-1596
    Keywords: Cranio-facial identification ; Facial reconstruction ; 3D Computer graphics ; Video superimposition ; Laser scanner
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine , Law
    Notes: Abstract A facial image was reconstructed from the skull, part of a complete skeleton found in woodland, of a male person who had hanged himself from a tree. In addition, video superimposition was carried out with antemortem photographs of a person suspected of being the victim, and a good match was obtained. In a further case, a cheaper video-transparency superimposition was carried out, with identity later being confirmed on the basis of dental records. The techniques and the problems encountered are discussed. According to our experience, 3D computer reconstruction and video superimposition have a useful role in the process of identification, particularly in the early stages of an investigation and when other more definitive methods may not be available.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 79 (1989), S. 205-210 
    ISSN: 1432-0533
    Keywords: Medulloblastoma ; Immunohistology ; Primitive neuroectodermal tumour ; Brain tumour
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Fifty paraffin-embedded medulloblastomas (31 in children and 19 in adults) were reacted with a panel of ten antibodies to glial, neuronal, mesodermal and epithelial antigens. The tumours were divided according to their histological features into three groups: classic, desmoplastic and highly vascular. Reactivity for glial fibrillary acidic protein was observed in 20 cases. Forty tumours reacted with PGP9.5 (neuronal marker) in clusters of poorly differentiated cells, cell cords and some scattered cells. Cells forming rosettes were mostly negative except for slight central reactivity. Eight of the 40 tumours contained neurofilaments. In scattered cells somatic reactivity for vimentin was found in 14 tumours. Ten cases showed positivity for S-100 with a nuclear and perinuclear pattern. No difference in reactivity in relation with age was observed. Desmoplastic medulloblastomas showed less reactivity for glial and neural markers. It was concluded that medulloblastoma shows degrees of differentiation as evidenced by the expression of various proteins. Differentiation occurs along two lines: glial and/or neuronal. Most tumours also contain a component of poorly differentiated cells which may differentiate into one of these two lines or act as primarily stem cells.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Experimental brain research 62 (1986), S. 312-320 
    ISSN: 1432-1106
    Keywords: Isolated frog labyrinth ; Excitatory-inhibitory rotational stimuli ; First order canal neuron dynamics ; Non-linearities
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary EPSPs and spikes were recorded at rest and during rotation from single fibres of the posterior nerve in the isolated frog labyrinth. The spike discharge properties of 57 units were examined at rest and during repetitive acceleratory-velocity steps. Forty of these units were subjected to excitatory steps of 5–12 s duration and 45% displayed an evident discharge adaptation. In the non-adapting units, the excitatory response also deviated from that expected on the basis of the torsion-pendulum model and exhibited an exponential time-course in only 36% of the fibres examined. The time constant T2 of the response rising phase was significantly longer than that of the decay (2.5 s versus 1.7 s). When all the 57 units were considered, a linear behaviour was found in 67%. The average gain in these linear units was 1.9 ± 1.4 spikes · s−1/deg · s−2. Adaptive fibres exhibited a lower resting firing rate and a higher gain (3.8 spikes/s and 2.3 spikes · s−1/deg · s−2, respectively) when compared with the non-adapting ones (7.1 spikes/s and 1.5 spikes · s−1/deg · s−2). An undershoot was present in 57% of the units; it increased with acceleration and was not strictly related to adaptation. Fifteen of the 40 units tested with the 5–12 s duration excitatory steps survived repeated inhibitory accelerations of the same duration. In these units a marked response asymmetry was evident since their resting activity could be abolished by accelerations not larger than 10 deg/s2. In 40% of the units inhibited by acceleration the mean response was proportional to the stimulus logarithm, while the others saturated for weak stimulations. A consistent overshoot of the discharge was evident in most of the units (60%). Analysis of the EPSP emission rates demonstrates that even a 10–20% increase in their frequency during excitation results in a two-three fold increase in the corresponding spike frequency. Similarly, a decrease of 15–35% in their numbers during inhibition is sufficient to completely block the spike firing. These findings reveal the high sensitivity of the afferent synapse, spike discharge being modulated by slight modifications in the release of the excitatory transmitter.
    Type of Medium: Electronic Resource
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