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  • 1
    Electronic Resource
    Electronic Resource
    Torticollis spasmodicus, Blepharospasmus und hemifazialer Spasmus Subjektive Bewertung der Therapie durch Patienten (1999)
    Springer
    Der Nervenarzt 70 (1999), S. 903-908 
    Details
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Torticollis spasmodicus ; Blepharospasmus ; Hemifazialer Spasmus ; Therapien ; Botulinumtoxin ; Key words Spasmodic torticollis ; Blepharospasm ; Hemifacial spasm ; Therapies ; Botulinum toxin
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Injections with botulinum toxin type A (BTX) are considered the first-line treatment for spasmodic torticollis (ST), blepharospasm (BL) and hemifacial spasm (HFS). Because BTX brings only temporary and partial relief, patients frequently try other additional therapies to minimize their symptoms. The subjective rating of all therapies ever tried by patients with ST, BL and HFS was evaluated by using a simple questionnaire. Two hundred questionnaires were considered (112 TS, 54 BL, 34 HFS). BTX was rated subjectively the best therapy in all three diagnostic groups (median: 2=good effect). Despite Citalopram and physiotherapy (median: 3=average effect), all other therapies were rated with a median of ≥4 (=minimal effect). Patients with ST tried 7.7, patients with BL 2.4 and patients with HFS 2.6 different types of therapy. In conclusion, BTX is the most effective treatment for patients with ST, BL and HFS, as rated subjectively. Further evaluation of therapies additional to BTX injections is recommended.
    Notes: Zusammenfassung Die Botulinumtoxinbehandlung (BTX) gilt als Therapie der Wahl bei Torticollis spasmodicus (TS), Blepharospasmus (BL) und hemifazialem Spasmus (HFS). Da bestehende Beschwerden mit BTX meist nur vorübergehend und manchmal nicht im ganzen Ausmaß beseitigt werden können, werden von Patienten immer wieder andere Behandlungsformen versucht. Mit einem einfachen Fragebogen wurde von Patienten mit TS, BL und HFS eine subjektive Beurteilung aller bisher versuchten Therapien eingeholt. Ausgewertet wurden 200 Fragebögen (112 TS, 54 BL, 34 HFS). BTX wurde in allen drei Diagnosegruppen als subjektiv wirksamste Therapie bewertet (Median: 2=gute Wirkung). Abgesehen von Citalopram und Physiotherapie (Median: 3=durchschnittliche Wirkung) beim TS wurden alle anderen Therapien mit einem Median von ≥4 (=minimale Wirkung) bewertet. Patienten mit TS haben im Durchschnitt 7,7, Patienten mit BL 2,4 und mit HFS 2,6 Behandlungsformen ausprobiert. Zusammenfassend ist BTX die subjektiv wirksamste Behandlung bei Patienten mit TS, BL und HFS. Weitere Untersuchungen über ergänzende Begleittherapien zur BTX-Behandlung sind erforderlich.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001150050594
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Unilateral stenosis of the vertebral artery — Secondary finding with no prognostic relevance? (1987)
    Springer
    European archives of psychiatry and clinical neuroscience 236 (1987), S. 230-234 
    Details
    ISSN: 1433-8491
    Keywords: Vertebral artery stenosis ; Cerebral angiography ; Cerebrovascular diseases ; Stroke ; Prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The outcome of 142 patients suffering from ischemic cerebral circulation disorders was followed up over a period of 33 months on average. The spontaneous course of 25 patients with unilateral, hemodynamically ineffective stenoses of the vertebral artery was compared with that of 107 patients without vertebral artery stenoses. Within the first 12 months, novel clinically manifest cerebrovascular events were observed in 16.0% of patients without vertebral artery stenosis (deaths 5.0%), but in only 4.3% of the patients with vertebral artery stenosis (no deaths). Within 30 months, only 2 of the 13 patients with vertebral artery stenosis had suffered a new cerebrovascular attack. At the end of the observation period, 39.3% of the patients without vertebral artery stenosis and 48.0% of the patients with vertebral artery stenosis were significantly disabled in their social life or had died. An additional unilateral hemodynamically irrelevant vertebral artery stenosis did not influence the rate of reinfarction or the remission of neurological deficits, independently of age, the degree of the circulatory disorder, the vascular territory involved, the presence of an organic psychosyndrome, or of additional stenoses in the carotid arteries. Consequently, a vertebral artery stenosis narrowing the vessel diameter to less than 1/3 is without prognostic relevance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00383853
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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