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  • 1
    ISSN: 1432-1920
    Keywords: Key words Ependymoma ; Posterior cranial fossa ; Children ; Magnetic resonance imaging ; Computed tomography ; Brain tumours
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied nine children with posterior cranial fossa ependymomas to identify specific neuroradiological features. Patients were studied preoperatively with CT and MRI; T1-, T2- and proton-density (PD)-weighted images were obtained. All children underwent surgery and a definite histopathological diagnosis was made. All the tumours grew into the fourth ventricle and caused dilatation of its upper part, which resembled a cap. All but one were separated from the vermis by a cleavage plane. In eight cases there was desmoplastic development through the foramina of the fourth ventricle, and five were heterogeneous due to necrosis and cystic change; one had a haemorrhagic area. In most cases the solid portion was isointense with grey matter on T1-weighted images, hyperintense on PD weighting, and isointense on T2-weighted images. On CT the tumour was isodense in six cases and calcification was detected in four. The presence of both desmoplastic development and a tumour/vermis cleavage plane in a posterior cranial fossa tumour isodense on CT is highly suggestive of ependymoma.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-1920
    Keywords: Ependymoma ; Posterior cranial fossa ; Children ; Magnetic resonance imaging ; Computed tomography ; Brain tumours
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We studied nine children with posterior cranial fossa ependymomas to identify specific neuroradiological features. Patients were studied preoperatively with CT and MRI; T1-, T2-and proton-density (PD)-weighted images were obtained. All children underwent surgery and a definite histopathological diagnosis was made. All the tumours grew into the fourth ventricle and caused dilatation of its upper part, which resembled a cap. All but one were separated from the vermis by a cleavage plane. In eight cases there was desmoplastic development through the foramina of the fourth ventricle, and five were heterogeneous due to necrosis and cystic change; one had a haemorrhagic area. In most cases the solid portion was isointense with grey matter on T1-weighted images, hyperintense on PD weighting, and isointense on T2-weighted images. On CT the tumour was isodense in six cases and calcification was detected in four. The presence of both desmoplastic development and a tumour/vermis cleavage plane in a posterior cranial fossa tumour isodense on CT is highly suggestive of ependymoma.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-1920
    Keywords: Key words Angioblastoma ; Fibromatosis ; Hamartoma ; Magnetic resonance imaging ; Spinal tumours ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a child aged 2 years presenting with delayed motor development. A thoracolumbar subcutaneous mass was noticed in the first months of life. MRI showed a low conus medullaris, confirmed the presence of the mass and detected a second solid lesion in the intradural space. Surgery confirmed that the two lesions were distinct, as on MRI. The histopathological features were in common with fibrous hamartoma of infancy, giant cell angioblastoma and the “diffuse type” of infantile fibromatosis. The presence of a low conus medullaris associated with a congenital clinical presentation suggested a disontogenetic aetiology.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-1920
    Keywords: Angioblastoma ; Fibromatosis ; Hamartoma ; Magnetic resonance imaging ; Spinal tumours ; Children
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We report a child aged 2 years. presenting with delayed motor development. A thoracolumbar subcutaneous mass was noticed in the first months of life. MRI showed a low conus medullaris, confirmed the presence of the mass and detected a second solid lesion in the intradural space. Surgery confirmed that the two lesions were distinct, as on MRI. The histopathological features were in common with fibrous hamartoma of infancy, giant cell angioblastoma and the “diffuse type” of infantile fibromatosis. The presence of a low conus medullaris associated with a congenital clinical presentation suggested a disontogenetic aetiology.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé L'étude des tumeurs de la fosse postérieure à l'aide d'un produit de contraste hydrosoluble introduit directement dans le 3ème ventricule visualise de fines structures anatomiques plus nettement que d'autres méthodes, ce qui est important pour l'obtention d'un diagnostic topographique précis en cas de processus expansif, condition essentielle pour un traitement correct. Les auteurs décrivent le mode d'exécution et les critères du diagnostic différentiel des diverses localisations.
    Abstract: Zusammenfassung Es wird über die Untersuchungen mit wasserlöslichen Kontrastmitteln bei Tumoren der hinteren Schädelgrube berichtet. Dabei wird das Kontrastmittel direkt in den 3. Ventrikel injiziert. Bei dieser Untersuchungsmethode sind die anatomischen Strukturen besser erkennbar als bei anderen Untersuchungen. Die Detail-Diagnostik ist besonders wertvoll für eine genaue topographische Diagnose der intracraniellen Raumforderungen. Die Untersuchungstechnik und die differentialdiagnostischen Kriterien für die unterschiedlichen Lokalisationen werden beschrieben.
    Notes: Summary The study of posterior fossa tumors with a watersoluble contrast medium introduced directly into the third ventricle demonstrates some anatomical structures more clearly than with other materials. This detail is useful for a precise topographical diagnosis of space-occupying lesions. The mode of execution and the differential diagnostic criteria for the various localizations are described from a study of 107 cases.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1432-1920
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé La présence d'un spasme artériel cérébral introduit un pronostic défavorable. Le mauvais pronostic peut être amélioré par le choix judicieux du moment de l'intervention chirurgicale, lorsque le spasme a diminué, et en appliquant la corticothérapie intrarachidienne. Le pronostic varie également en fonction de l'âge du malade, de la topographie de l'anévrisme et de la disposition du cercle de Willis.
    Abstract: Zusammenfassung Der Nachweis von cerebralen Gefäßspasmen ist ein ungünstiges prognostisches Zeichen, wie die Autoren an ihrem eigenen Krankengut nachweisen konnten.
    Notes: Summary The presence of a cerebral arterial spasm carries an unfavourable prognostic significance. The poor prognosis can be improved by wisely choosing themoment of operation, to be performed once the spasm has subsided, and by applying intrathecal corticoid therapy. It appears also modified in relation to various factors, such as age of the patient, topography of the aneurysm and pattern of Willis's circle.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Neuroradiology 31 (1990), S. 512-522 
    ISSN: 1432-1920
    Keywords: Occult spinal dysraphism ; Lipoma ; Tethered cord ; Spinal cord ; Caudal regression syndrome ; Developmental mass lesions
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We present a retrospective study of occult spinal dysraphism in 47 children aged 0 to 14 years, all studied with plain X-rays, 60% with CT and myelo-CT, and 40% with MR. We consider the classification and grading of these malformations, clinical, neuroradiological patterns, and indications for surgery. In the light of our findings and of the published data MR emerges as the key investigation. Only in a few cases of great anatomical complexity is it now necessary to perform CT and myelo-CT as well. A case in point is when the conus and thickened filum terminale are inextricably bound together and can no longer be considered separate structures. We propose the term “neurofibrous structure” to define the conus-thickened-filum-terminale unit when these structure are no longer distinguishable.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-1920
    Keywords: Key words Medulloblastoma ; Childhood brain tumours ; Magnetic resonance imaging ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our purpose was to determine whether medulloblastoma (MB) shows specific neuroradiological features which may be employed in differential diagnosis from other common posterior cranial fossa tumours in childhood. Preoperative MRI was performed on 20 children with MB, and preoperative CT in 17 of them. All underwent surgery and histopathological diagnosis. There was a constant relationship between high density on CT and low signal on T1-weighted images. Signal behaviour on T2-weighted images and the degree of contrast enhancement were more variable. Most tumours arose in the midline, from the cerebellar vermis, involving the fourth ventricle, but hemisphere and extra-axial neoplasms were also seen. The combination of high density on CT and low signal on T1-weighted images is highly suggestive of MB and may assist preoperative differential diagnosis from other posterior cranial fossa tumours.
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-1920
    Keywords: Medulloblastoma ; Childhood brain tumours ; Magnetic resonance imaging ; Computed tomography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Our purpose was to determine whether medulloblastoma (MB) shows specific neuroradiological features which may be employed in differential diagnosis from other common posterior cranial fossa tumours in childhood. Preoperative MRI was performed on 20 children with MB, and preoperative CT in 17 of them. All underwent surgery and histopathological diagnosis. There was a constant relationship between high density on CT and low signal on T1-weighted images. Signal behaviour on T2-weighted images and the degree of contrast enhancement were more variable. Most tumours arose in the midline, from the cerebellar vermis, involving the fourth ventricle, but hemisphere and extra-axial neoplasms were also seen. The combination of high density on CT and low signal on T1-weighted images is highly suggestive of MB and may assist preoperative differential diagnosis from other posterior cranial fossa tumours.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    Acta neuropathologica 4 (1965), S. 538-558 
    ISSN: 1432-0533
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Die vorliegende Arbeit behandelt das histochemische Verhalten der Dehydrogenasen verschiedener Zelltypen in Tumoren des Nervensystems. Die von uns beobachteten Unterschiede in den Reaktionsergebnissen wurden nach den folgenden Gesichtspunkten untersucht: a) Beschreibung der histochemischen Reaktionen in den verschiedenen Tumortypen. b) Reaktionsunterschiede im Zusammenhang mit dem Differenzierungsgrad der Zellelemente, der embryonalen Grundlinien folgt. c) Reaktionsunterschiede in Abhängigkeit von Proliferationszonen mit zahlreichen atypischen Mitosen und ungenügender Zellreife. d) Unterschiede im Zusammenhang mit reaktiven oder regressiven Vorgängen.
    Notes: Summary The present research has pointed out some histochemical aspects of the oxidative metabolism of the various types of cells present in tumors of the nervous system. The variations in the reactions we observed were examined from the following points of view: a) Description of histochemical reactions in the various oncotypes. b) Variations in relation to the stage of differentiation of cellular elements, the evolution of which follows embryogenetic lines. c) Variations in relation to arrangements showing rapid growth with numerous and atypical mitoses and a deficient maturation of the cell. d) Variations in relation to reactive or regressive processes.
    Type of Medium: Electronic Resource
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