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  • 1
    Electronic Resource
    Electronic Resource
    Korrelation einer „Latenten Hyperthyreose“ mit psychischen und somatischen Veränderungen (1987)
    Springer
    Journal of molecular medicine 65 (1987), S. 264-273 
    Details
    ISSN: 1432-1440
    Keywords: Preclinical hyperthyroidism ; Psychological changes ; Clinical symptoms
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The study reported here was undertaken to establish the degree to which a person in a preclinical state of hyperthyroidism, with (by definition) euthyroid T3 and T4 levels but suppressed TRH on testing, already exhibits psychological changes and clinical symptoms. Two groups of 20 patients each, with clear clinical and preclinical hyperthyroidism (as defined by laboratory parameters), were studied, as well as a group of 20 controls. The subjects' psychological state of mind was investigated using self-rating scales, including the state-trait-anxiety inventory (STAI), „Befindlich-keits“-Skala (Bf-S'), depression scale (D-S'), and a list of adjectives (EWL-K) with 14 different aspects of affective moods. Cognitive achievements were evaluated using the d2 test. Subjects were examined for somatic symptoms in accordance with Crooks' index of hyperthyroidism. The results clearly showed that typical psychological and somatic changes are already present in preclinical hyperthyroidism, these changes being partly identical with those of definite hyperthyroidism. In both patient groups, a significant increase in anxiety, a sense of not feeling well, and emotional irritability were found, as well as a tendency towards depressiveness, and an increased lack of vitality and activity. Attentiveness and concentration in both patient groups were lower than in the control group. Both patient groups showed the same prevalence of symptoms, such as palpipations, preference of cold over heat, excessive sweating, nervousness, fine digital tremor, and increased heart rate. With regard to the results, the diagnosis “preclinical hyperthyroidism” thus gains importance. Further prospective studies are required to answer the question whether antithyroidal treatment will influence the described psychological and somatic state of patients with preclinical hyperthyroidism.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01773447
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Dynamische In-vivo- Anpreßdruckmessung zur Qualitätskontrolle der Kompressionsstrümpfe (1997)
    Springer
    Der Hautarzt 48 (1997), S. 471-476 
    Details
    ISSN: 1432-1173
    Keywords: Schlüsselwörter Kompressionstherapie ; Dynamische Anpreßdruckmessung ; Mikrodruckmeßsonde ; Compliance ; Key words Compression therapy ; Dynamic pressure measurement ; Piezometric microprobe ; Compliance
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary The well-documented positive effect of compression stocking therapy on the venous macro- and microhemodynamics of the legs can only be attained if the stockings fit well. In order to determine the effective pressure exerted by compression stockings, we usually deleted in US journals. One can get this out of journal and author’s address have developed a new measuring method based on piezoresistant microprobes and a microprocessor unit. With our 2-mm-thick, 5-mm diameter probe, the pressure between the compression stocking and skin can be measured at any location desired. A temporal resolution of 50 Hz makes it possible to carry out dynamic measurements while the patient is walking or performing exercises on tiptoes. Here we present 4 typical cases out of a total of over 80 which we have evaluated. We have decided empirically that the pressure exerted by a class-2 compression stocking on the skin at the height of the ankles (b-position) should not exceed 70 mm Hg while resting and a peak of 110 mm Hg while exercising on tiptoes. At the middle of the calf (c-position) these values should not exceed 60 mm Hg at rest and 80 mm Hg on tiptoes. The pressure should decrease from the distal to proximal direction in order to produce a drainage gradient. We have found empirically that a pressure gradient of 30–40% from the b to the c measurement is favorable. Too high a proximal pressure or too high a pressure on a part of the lower leg causes pain and swelling. Too low a pressure, on the other hand, does not produce the desired vascular effect and alleviation of symptoms. Although dynamic pressure measurements take about 20–30 minutes per leg, they markedly improve patient compliance with compression therapy.
    Notes: Zusammenfassung Die gut dokumentierte günstige Wirkung der Kompressionstherapie mit Kompressionsstrümpfen auf die venöse Makro- und Mikrohaemodynamik der Beine läßt sich nur mit gut angepaßten Strümpfen erreichen. Um den effektiven Anpreßdruck zu bestimmen, wurde an der Universitäts-Hautklinik Tübingen eine neue Meßmethode, basierend auf piezoresistiven Mikromeßsonden und einer Mikroprozessoreinheit, entwickelt. Der Anpreßdruck zwischen Kompressionsstrumpf und Haut kann mit den 2 mm dicken und 5 mm im Durchmesser großen Sonden an beliebigen Hautarealen gemessen werden. Die zeitliche Auflösung von 50 Hz erlaubt dynamische Messungen beim Gehen oder bei Zehenspitzenständen. Es werden hier 4 typische Fallbeispiele aus bisher über 80 Messungen dargestellt. Empirisch wurde ermittelt, daß der Anpreßdruck eines Strumpfes mit Kompressionsklasse 2 auf die Haut auf Knöchelhöhe (b-Maß) 70 mmHg in Ruhe und 110 mmHg Spitzendruck bei Zehenspitzenständen bzw. 60 mmHg in Ruhe und 80 mmHg bei Zehenständen in Wadenmitte (c-Maß) nicht überschreiten sollte. Der Anpreßdruck soll von distal nach proximal abfallen, um entstauend zu wirken. Empirisch wurden Druckdifferenzen von 30–40% vom b- zum d-Maß als günstig ermittelt. Zu hohe proximale Drucke bzw. zu hohe Drucke an einem Unterschenkelsegment verursachen Schmerzen und Schwellung. Zu niedrige Drucke führen nicht zur Entstauung und gewünschten Beschwerdelinderung. Die Compliance der Patienten hinsichtlich der Kompressionstherapie läßt sich durch eine dynamische Anpreßdruckmessung, die allerdings etwa 20–30 min Zeit pro Bein in Anspruch nimmt, deutlich verbessern.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001050050612
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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