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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    International journal of colorectal disease 13 (1998), S. 43-47 
    ISSN: 1432-1262
    Keywords: Key words Diverticular disease ; Laparoscopically assisted sigmoid resection ; Open sigmoid resection ; Recovery ; Morbidity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Le but de cette étude est d'évaluer le devenir des patients ayant subi une sigmoïdectomie laparoscopique pour maladie diverticulaire. Vingt-neuf patients consécutifs ont été traités chirurgicalement pour une diverticulite colique. Vingt-sept des cas ont pu être opérés par laparoscopie, L'étude des dossiers cliniques d'un groupe-contrôle de 34 patients subissant une résection ouverte a servi de comparaison. Le taux de conversion est de 7,5%. Par laparoscopie, la durée de l'intervention chirurgicale a été plus longue (165 vs 121 minutes, P〈0,05), les pertes sanguines (182 vs 352 ml, P〈0,05) et les transfusions sanguines moindres (0 vs 16%). L'incidence des complications suivant la laparoscopie a été inférieure (2 fuites anastomotiques, 2 infections de plaie) en comparaison à la chirurgie conventionnelle. La convalescence du groupe laparoscopique a été plus rapide et la durée d'hospitalisation réduite (7,9 vs 14,3 jours, P〈0,05). Dans le groupe laparascopique, les douleurs au repos et aux mouvements ont été inférieures. Let coût du geste chirurgical laparoscopique a été inférieur en comparaison à la résection conventionelle (7185 vs 8975 DM). Dans cette série, la résection sigmoïdienne par laparoscopie pour maladie diverticulaire est sûre et plus rapide, la durée de guérison est plus rapide, la durée d'hospitalisation plus brève et les patients ont présenté moins de douleurs dans le groupe laparoscopique en comparaison avec la chirurgie conventionelle.
    Notes: Abstract This study evaluated outcome in patients undergoing laparoscopically assisted sigmoid resection for diverticular disease. A total of 29 consecutive patients were treated surgically for colonic diverticulitis; in 27 of these laparoscopy was performed. The review of medical records from a control group of 34 patients undergoing open resection were used for comparison. The conversion rate was 7.5%. Using the laparoscopic technique the duration of surgery was longer (165 vs. 121 min, P〈0.05), blood loss less (182 vs. 352 ml, P〈0.05), and subsequent blood transfusion less (0 vs. 61%). The incidence of complications following laparoscopic resection was lower (two anastomotic leakages, two wound infections) than in the conventional group. Convalescence in the laparoscopic group was more rapid and hospital stay shorter (7.9 vs. 14.3 days, P〈0.05). In the laparoscopic group patients expressed less pain at rest and in motion. The cost of the laparoscopically assisted procedure was less than that of conventional resection (7185 vs. 8975 DM). In this series laparoscopically assisted sigmoid resection for diverticulitis proved safe. Recovery was faster, hospital stay was shorter, and patients expressed less pain than in conventional open surgery.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 383 (1998), S. 26-34 
    ISSN: 1435-2451
    Keywords: Key words Sepsis ; Mediators ; Antimediators ; Modulation ; Study design ; Complexity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sepsis, the systemic response (specific and non-specific) of the body to an infection, is an increasing clinical problem. During the last 30 years, nearly 50 clinical trials involving more than 10,000 patients have failed to demonstrate improvement of patients' outcome with different “anti-mediator” strategies. The wrong conceptional approaches to interact with the complex mediator network and flaws in study design and conduct are the main reasons for this disappointing situation. We learned, however, that the systemic host response is more than persistent uncontrolled inflammation; it is also a stimulation of the counter regulatory network. Although it is important to analyse the complex picture, we have now reached a point where more sophisticated strategies for describing complexity and novel attempts for synthesis are needed. Along this line, improved study designs (decrease of “signal-to-noise ratio”) are mandatory. In addition, secondary preventive strategies are emphasised.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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