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  • 1
    Electronic Resource
    Electronic Resource
    Role of Gestational Age and Body Weight on Doppler Transmitral Flow Velocity Pattern in Very Low Birth Weight Infants (1996)
    Springer
    Pediatric cardiology 17 (1996), S. 242-245 
    Details
    ISSN: 1432-1971
    Keywords: Key words: Doppler echocardiography — Transmitral flow — Very low birth weight infant
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Doppler transmitral flow velocity was measured in premature infants. The early diastolic peak velocity, the peak velocity of early diastole/peak velocity of atrial contraction ratio, and total flow velocity–time integral increased significantly with advancing gestational age and body weight. The peak filling rate normalized to stroke volume (NPFR) did not correlate with gestational age or body weight. Moreover, mean NPFR was not significantly different between premature and term infants. Thus NPFR demonstrates that changes in the left ventricular filling patterns with advancing gestational age and increasing body size are related to the progressive increase in loading conditions, rather than to sequential changes in myocardial properties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002469900053
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Ultrastructural study of the childhood mitochondrial myopathic syndrome associated with lactic acidosis (1982)
    Springer
    European journal of pediatrics 139 (1982), S. 25-30 
    Details
    ISSN: 1432-1076
    Keywords: Mitochondrial myopathic symdrome ; Lactic acidosis ; Endothelium ; Ultrastructural study
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The quadriceps femoris muscle and the muscularis mucosae of the rectum from two children with mitochondrial myopathic syndrome associated with lactic acidosis were studied by electron microscopy. Striking morphological abnormalities of mitochondria were noted not only in the skeletal but also in the smooth muscle cells. Endothelial cells of blood capillaries distributed in these affected muscles were so greatly swollen that the capillary lumen was almost occluded. In contrast, surface epithelial and glandular epithelial cells of the rectum contained normal mitochondria, and fenestrated capillaries in the propria mucosae remained intact. Long-term ischemia resulting from occlusive changes of the capillary wall may be responsible for the mitochondrial alterations of muscle cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00442074
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    A case of tubulo-interstitial nephritis with exfoliative dermatitis and hepatitis due to phenobarbital hypersensitivity (1992)
    Springer
    European journal of pediatrics 151 (1992), S. 69-72 
    Details
    ISSN: 1432-1076
    Keywords: Phenobarbital ; Interstitial nephritis ; Toxic hepatitis ; Exfoliative dermatitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Severe exfoliative dermatitis and liver dysfunction developed in a 5-year-old girl 3 weeks after initiation of phenobarbital therapy. Liver function improved gradually after discontinuation of phenobarbital. During the convalescent stage an initially mild renal dysfunction was exacerbated by episodes of post-transfusion haemolysis. Liver biopsy revealed moderate parenchymal damage with subacute cellular infiltration. Renal biopsy demonstrated the cardinal findings of interstitial nephritis, excluding the possibility of acute tubular necrosis caused by haemolysis. Serial lymphocyte transformation studies and skin patch tests gave positive results for phenobarbital, supporting the view that these were unusual complications of phenobarbital hypersensitivity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02073898
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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