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  • Life Sciences  (3)
  • Histochemistry  (2)
  • Recurrence intervals  (2)
  • 1
    Electronic Resource
    Electronic Resource
    The lipopigments in human brain tissue necroses (1980)
    Springer
    Acta neuropathologica 52 (1980), S. 141-145 
    Details
    ISSN: 1432-0533
    Keywords: Brain tissue necrosis ; Phagocytic pigments ; Ceroid ; Pigment maturation ; Histochemistry
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The ceroid pigment of macrophages were subdivided into four different types according to their own color and their ability to stain with luxol fast blue. With reference to this mode a series of more than 200 brain infarcts which had happened 1 day to 56 years before death, was examined systematically. According to the results the ceroid variants do not only succeed one another chronologically but they also represent histochemically successive phases of development which correspond to the progressive auto-oxidation of unsaturated lipids. The occurrence of the different stages is chronologically defined. During this development cortical and subcortical macrophages show different speeds in the ageing process of their pigments. There is no evidence for an essential participation of proteins in the maturation of the ceroid. Not during any phase of development is the reaction pattern identical with that of neuronal and glial lipofuscin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688012
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  • 2
    Electronic Resource
    Electronic Resource
    Supratentorial recurrences of gliomas. Morphological studies in relation to time intervals with astrocytomas (1977)
    Springer
    Acta neurochirurgica 37 (1977), S. 75-91 
    Details
    ISSN: 0942-0940
    Keywords: Supratentorial astrocytomas ; Recurrences of astrocytomas ; Classification of gliomas ; Recurrence intervals ; Radiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report 137 recurrent supratentorial astrocytomas. The primary tumours diagnosed on the basis of a grading system with three stages were 72 astrocytomas I and 65 astrocytomas II. In the first group 14% of the recurrences were not changed, 55.5% became astrocytomas II, and 30.5% became glioblastomas. In the second group 55.4% were unchanged, and 44.6% became glioblastomas. The postoperative intervals until reintervention or death were statistically examined. It seems that the recurrence time chiefly depends on the nature of the primary tumour. The transformation of an astrocytoma I to a glioblastoma takes longer than the transformation of an astrocytoma II into a glioblastoma. In about two thirds of all astrocytomas an increase of malignancy is to be expected. From the histological picture it is not possible in an individual case to predict the likelihood or speed of malignant change. With regard to the effect of irradiation the authors conclude that radiotherapy most probably does not produce malignancy.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01401927
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  • 3
    Electronic Resource
    Electronic Resource
    The lipopigments in human brain tissue necroses (1980)
    Springer
    Acta neuropathologica 52 (1980), S. 147-151 
    Details
    ISSN: 1432-0533
    Keywords: Special chromolipids ; Histochemistry ; Fluorescent microscopy ; Hemorrhagic brain tissue necroses
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A serial and comparative histochemical examination of lipopigments in human brain tissue necroses led to a more exact characterization of a chromolipid called “hemoceroid”. It arises only in necroses with hemorrhages and not in anemic necroses nor in subdural hematomas. Its histochemical properties differ from those of all developmental stages of ceroid. An ageing phenomenon is absent. The very intense autofluorescence of the thick, clotted pigment ist striking. Hemoceroid seems to arise extracellularly and is absorbed secondarily by macrophages.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00688013
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  • 4
    Electronic Resource
    Electronic Resource
    Supratentorial recurrences of gliomas. Morphological studies in relation to time intervals with oligodendrogliomas (1977)
    Springer
    Acta neurochirurgica 39 (1977), S. 15-25 
    Details
    ISSN: 0942-0940
    Keywords: Supratentorial oligodendrogliomas ; Recurrences of oligodendrogliomas ; Classification of gliomas ; Recurrence intervals ; Radiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary On the basis of a three stage grading system we report 23 stage one recurrent oligodendrogliomas (O 1), and 29 stage two recurrent oligodendrogliomas (O 2). In the O 1 group after the first interval 15 became O 2 and 2 became glioblastomas. Twenty tumours of the O 2 group after the first interval were not changed, three became oligodendroglioma-astrocytomas stage 2, and six became glioblastomas. The time relation for the recurrent phase in the primary O 1 group is calculated as 42 months, and in the primary O 2 group as 22 months, but this is without significance. For the development of malignancy, especially for the change to glioblastoma, a prominent participation by transformed local astrocytes seems to be essential. Postoperative irradiation most probably does not favour malignant change. A prolongation of the expectation of life by radiotherapy is not noticed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01405237
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  • 5
    Electronic Resource
    Electronic Resource
    Construction of a promoter-probe vector for the methanol-utilizing bacterium acetobacter methanolicus MB 58 (1989)
    Berlin : Wiley-Blackwell
    Acta Biotechnologica 9 (1989), S. 219-225 
    Details
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: We report here the construction of a promoter-probe vector, pRS2, which can be utilized in either Acetobacter methanolicus MB 58 or Escherichia coli due to the presence of broad-host-range replicon RSF 1010. The vector provides several unique restriction sites for promoter cloning as well as resistance markers for the selection of transformants. The promoter-probe vector was constructed by inserting an EcoRI-SalI-polylinker fragment of pUC 19 into EcoRI/SalI digested pMK 16. The resulting plasmid, pRS1, was cloned into the unique EcoRI site of the broad-host-range plasmid RSF 1010.The vector was used to clone promoter-containing sequences derived from the A. methanolicus MB 58 chromosome as well as the E. coli lac-promoter.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/abio.370090306
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Structure, function, and genetics of ribosomes. Springer Series in Molecular biology (Series Editor: Alexander RICH). Berlin, Heidelberg, New York, London, Paris, Tokyo: Springer-Verlag, 1986. 810 pp., 294 fig., DM, ISBN 0-387-96 233-6 (1988)
    Berlin : Wiley-Blackwell
    Acta Biotechnologica 8 (1988), S. 284-284 
    Details
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/abio.370080322
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  • 7
    Electronic Resource
    Electronic Resource
    Construction of broad-host-range plasmids for the expression of heterologous genes in Acetobacter methanolicus B58 (1994)
    Berlin : Wiley-Blackwell
    Acta Biotechnologica 14 (1994), S. 141-151 
    Details
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: The construction of different plasmids reported here on the basis of a broad-host-range RSF1010 replicon allows an efficient expression of heterologous genes in the acidophilic methanol-assimilating bacterium Acetobacter methanolicus B58.The promoter-probe vector pRS201 was used for the identification and isolation of the promoter containing sequences derived from the DNA of the Acetobacter phage Acm1. Further, this plasmid was coupled with the Escherichia coli promoters tac and pr creating the expression vectors pRS201tac and pRS201pr, respectively. After the insertion of the chloramphenicol acetyltransferase (cat) gene of the cloned promoters downstream, the chloramphenicol acetyltransferase (CAT) was determined in a cell-free extract of both E. coli and A. methanolicus.Using E. coli promoters as well as promoters of the Acetobacter phage Acm1 arranged in tandem with the promoters of the heterologous genes to be expressed, the pectat lyase gene (ptlB) of Erwinia carotovora and the threonine A gene (thrA) of E. coli were successfully expressed in A. methanolicus.The stability of recombinant plasmids under various conditions in A. methanolicus strains was tested using antibiotic-free media.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/abio.370140205
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