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  • Organic Chemistry  (4)
  • Polymer and Materials Science  (4)
  • Key words Triticum aestivum  (2)
  • Magnetic resonance imaging  (2)
  • RFLP analysis  (2)
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  • 1
    Digitale Medien
    Digitale Medien
    Lhermitte-Duclos disease associated with syringomyelia (1996)
    Springer
    Neuroradiology 38 (1996), S. 529-531 
    Details
    ISSN: 1432-1920
    Schlagwort(e): Key words Lhermitte-Duclos disease ; Dysplastic gangliocytoma ; Magnetic resonance imaging ; Syringomyelia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A 23-year-old man presented with a 2-week history of intracranial hypertension. CT showed a large, nonenhancing cerebellar mass with surrounding calcification and displacement of the fourth ventricle. MRI revealed a septate lesion, with low signal on T1-weighted and high signal on T2-weighted images. The cerebellar tonsils were displaced below the foramen magnum and there was associated syringomyelia. The MRI features were characteristic of Lhermitte-Duclos (LD) disease (dysplastic gangliocytoma) and the diagnosis was confirmed following surgery. In this case, we emphasise the usefulness of MRI in the diagnosis of LD disease and consider the possible pathogenesis of the associated syringomyelia.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00626089
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  • 2
    Digitale Medien
    Digitale Medien
    Lhermitte-Duclos disease associated with syringomyelia (1996)
    Springer
    Neuroradiology 38 (1996), S. 529-531 
    Details
    ISSN: 1432-1920
    Schlagwort(e): Lhermitte-Duclos disease ; Dysplastic gangliocytoma ; Magnetic resonance imaging ; Syringomyelia
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract A 23-year-old man presented with a 2-week history of intracranial hypertension. CT showed a large, nonenhancing cerebellar mass with surrounding calcification and displacement of the fourth ventricle. MRI revealed a septate lesion, with low signal on T1-weighted and high signal on T2-weighted images. The cerebellar tonsils were displaced below the foramen magnum and there was associated syringomyelia. The MRI features were characteristic of Lhermitte-Duclos (LD) disease (dysplastic gangliocytoma) and the diagnosis was confirmed following surgery. In this case, we emphasise the usefulness of MRI in the diagnosis of LD disease and consider the possible pathogenesis of the associated syringomyelia.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00626089
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  • 3
    Digitale Medien
    Digitale Medien
    Location and mapping of the powdery mildew resistance gene MlRE and detection of a resistance QTL by bulked segregant analysis (BSA) with microsatellites in wheat (2000)
    Springer
    Theoretical and applied genetics 100 (2000), S. 1217-1224 
    Details
    ISSN: 1432-2242
    Schlagwort(e): Key words Triticum aestivum ; Blumeria graminis f. sp. tritici ; QTL mapping ; Molecular markers ; Disease resistance
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract  Powdery mildew (Blumeria graminis f. sp. tritici) is one of the most damaging diseases of wheat (Triticum aestivum). The objective of this study was to locate and map a recently identified powdery mildew resistance gene, MlRE, carried by the resistant line RE714 using microsatellites uniformly distributed among the whole genome together with a bulked segregant analysis (BSA). The bulks consisted of individuals with an extreme phenotype taken from a population of 140 F3 families issued from the cross between RE714 (resistant) and Hardi (susceptible). The population had been tested with three powdery mildew isolates at the seedling stage. Qualitative interpretation of the resistance tests located the MlRE gene on the distal part of the long arm of chromosome 6A. A subsequent quantitative interpretation of the resistance permitted us to detect another resistance factor on a linkage group assigned to chromosome 5D, which was constructed with microsatellites for which a polymorphism of intensity between bulks was observed. This quantitative trait locus (QTL) explained 16.8– 25.34% of the total variation. An interaction between both the resistant factor (MlRE and the QTL) was found for only one of the isolates tested. This study shows the advantage of making a quantitative interpretation of resistant tests and that the use of microsatellites combined with BSA is a powerful strategy to locate resistance genes in wheat.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s001220051427
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  • 4
    Digitale Medien
    Digitale Medien
    An intervarietal molecular marker map in Triticum aestivum L. Em. Thell. and comparison with a map from a wide cross (1997)
    Springer
    Theoretical and applied genetics 94 (1997), S. 367-377 
    Details
    ISSN: 1432-2242
    Schlagwort(e): Key words Triticum aestivum ; Doubled haploids   ; Intervarietal map ; Distortion segregation ; Genetic map comparison
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract  An intervarietal molecular marker map covering most of the nuclear genome was developed in Triticum aestivum. One hundred and six androgenetic-derived doubled haploid lines obtained from the F1 between monosomics of ‘Chinese Spring’ and ‘Courtot’ were analysed for genetic mapping. The map covered 18 of the 21 chromosomes with an identical distribution of markers in the A and B genome, and only small segments of the D genome. Distorted markers were mapped using Bailey’s 2-point method and revealed skewed regions on 1A, 1DS, 2A, 2B, 4AS and 6B. Comparison with a wide cross [‘Opata’×Synthetic hexaploid (T. tauschii/‘Altar 84’)] showed colinearity for markers on homologous chromosomes, but revealed a large proportion (25%) of markers mapped on non-homoeologous chromosomes, i. e. heterologous markers. The origin of the material and distortion segregation are discussed with particular emphasis on investigations of D-genome markers.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/s001220050425
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  • 5
    Digitale Medien
    Digitale Medien
    Study of androgenetic performance and molecular characterisation of a set of wheat-rye addition lines (1994)
    Springer
    Theoretical and applied genetics 89 (1994), S. 982-990 
    Details
    ISSN: 1432-2242
    Schlagwort(e): RFLP analysis ; Wheat-rye addition lines ; Chromosomal rearrangements ; Anther culture ; Regeneration
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract Rye chromosomes of wheat-rye addition lines were successfully identified by means of an RFLP analysis with 30 probes. Our results are in agreement with previous cytological data concerning the identity of lines F (+1R), D (+2R), C (+3R), A (+4R), E (+5R) and B (+7R). Two categories of chromosomal rearrangements have been distinguished, namely: (1) deletions: the current line D possesses a chromosome 2R deleted on its short arm and the line G a chromosome 3R deleted on its long arm; we have also noticed a deletion on the long arm of wheat chromosome 1A in line F61; and (2) evolutionary reciprocal translocations in rye relative to wheat which have been previously mentioned in the literature. The anther culture response of the different lines was studied. A significant difference between ‘FEC 28’ and the addition lines was observed for embryo production and plant regeneration. It appears that genes located on ‘S 10’ chromosome arm 3RL and on ‘FEC 28’ chromosome arm 1AL increase embryo frequency whereas gene(s) located on ‘S 10’ chromosome 5R reduce(s) it. Plant regeneration results suggest that genes increasing regeneration ability and green-plant frequency are located on ‘S 10’ chromosome 4R. The long arm of chromosome 1A seems to be involved positively in green-plant regeneration whereas chromosomes 1R and 3R limit plant regeneration.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00224528
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  • 6
    Digitale Medien
    Digitale Medien
    RFLP analysis of an Aegilops ventricosa chromosome that carries a gene conferring resistance to leaf rust (Puccinia recondita) when transferred to hexaploid wheat (1995)
    Springer
    Theoretical and applied genetics 90 (1995), S. 1042-1048 
    Details
    ISSN: 1432-2242
    Schlagwort(e): RFLP analysis ; Whea ; Aegilops ventricosa ; Leaf rust resistance
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie
    Notizen: Abstract RFLP analysis has been used to characterise XMv, a chromosome of Aegilops ventricosa present in a disomic addition line of wheat. This chromosome is known to carry a major gene conferring resistance to leaf rust (Lr). The analysis demonstrated that XMv is translocated with respect to the standard wheat genome, and consists of a segment of the short arm of homoeologous group 2 attached to a group 6 chromosome lacking a distal part of the short arm. Lr was located to the region of XMv with homoeology to 2S by analysis of a leaf rust-susceptible deletion line that was found to lack the entire 2S segment. Confirmation and refinement of the location of Lr was obtained by analysis of a spontaneous resistant translocation in which a small part of XMv had been transferred to wheat chromosome 2A.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF00222919
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  • 7
    Digitale Medien
    Digitale Medien
    Peptide-bond distortions and the curvature of α-helices (1986)
    New York : Wiley-Blackwell
    Biopolymers 25 (1986), S. 1087-1093 
    Details
    ISSN: 0006-3525
    Schlagwort(e): Chemistry ; Polymer and Materials Science
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Solvent accessible peptide bonds in proteins exhibit a 1-3° compression of the OCN bond angle and a corresponding expansion of the NCCa bond angle, relative to buried peptide bonds. These changes are consistent with an increase in hydrogen bonding to the carbonyl oxygen accompanying solvent exposure (J. D. Dunitz and F. K. Winkler, (1975) Acta Cryst. B31, 251-263). For amphiphilic structures such as α-helices, systematic differences in peptide-bond geometry between solvent-exposed and buried residues will generate significant curvature. A decrease of 4° in the OCN bond angle between hydrophilic and hydrophobic sides of an amphiphilic helix will lead to smooth bending, with a radius of curvature of about 70 Å. This curvature is in the range observed for α-helices in proteins. Helix curvature is estimated to have only a small effect on the magnitude and direction of the helical dipole moment.
    Zusätzliches Material: 4 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/bip.360250609
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  • 8
    Digitale Medien
    Digitale Medien
    (25 S)-1α, 25, 26-Trihydroxycholecalciferol, a New Vitamin D3 Metabolite: Synthesis and Absolute Stereochemistry at C(25) (1981)
    New York, NY : Wiley-Blackwell
    Helvetica Chimica Acta 64 (1981), S. 2138-2141 
    Details
    ISSN: 0018-019X
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: The 1α, 25, 26-trihydroxy metabolite of vitamin D3, isolated from bovine serum, was shown to possess the (25 S)-configuration by HPLC. comparison of the 1, 3, 26-triacetate derivative with authentic (25 R)- and (25 S)-samples. The convergent synthesis of (25 R)-1α, 25, 26- and (25 S)-1α, 25, 26-trihydroxycholecalciferols (10a) and (10b) has been accomplished.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/hlca.19810640718
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  • 9
    Digitale Medien
    Digitale Medien
    Azole. 22.21. Mitt.: BERNARD, M. K.; WRZECIONO, U.: Pharmazie 43 (1988) 723.. 1H- und 13C-NMR Untersuchungen an isomeren 3- und 5-Amino-pyrazol-Derivaten (1989)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 331 (1989), S. 600-610 
    Details
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Azoles. 22. 1H- and 13C-N.M.R. Investigation of Isomeric-3 and 5-Amino-Pyrazole DerivativesThe 1H- and 13C-n.m.r. spectra of nine pairs of isomeric 3- and 5-amino-pyrazole derivatives 1a - 1i and 2a - 2i and some of their acetylderivatives have been assigned and discussed. It has been found that 1H- and 13C-n.m.r. spectroscopy is a useful tool for differentation of the above mentioned 3- and 5-amino-isomers.
    Zusätzliches Material: 1 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prac.19893310409
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  • 10
    Digitale Medien
    Digitale Medien
    Azole. 23.22. Mitt.: BERNARD, M. K.; WRZECIONO, U.: J. prakt. Chem. 331 (1989) 600. Massenspektrometrische Untersuchungen an Derivaten der β-(Pyrazol-4-yl)acryl- bzw. -propionsäure und (Pyrazol-4-yl)methylenmalonsäure (1989)
    New York, NY : Wiley-Blackwell
    Journal für Praktische Chemie/Chemiker-Zeitung 331 (1989), S. 677-684 
    Details
    ISSN: 0021-8383
    Schlagwort(e): Chemistry ; Organic Chemistry
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Chemie und Pharmazie
    Notizen: Azoles. Mass Spectrometric Studies on Derivatives of β-(Pyrazole-4-yl) Acrylic or -Propionic Acid and Pyrazole-4-yl Methylenemalonic Acid
    Zusätzliches Material: 3 Tab.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/prac.19893310420
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