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  • 1
    Electronic Resource
    Electronic Resource
    Voltage-Dependent Block of the Na-Ca Exchanger in Heart Muscle Examined Using Giant Excised Patches from Guinea Pig Cardiac Myocytes (1991)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 639 (1991), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1991.tb17302.x
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  • 2
    Electronic Resource
    Electronic Resource
    Intake of unsaturated fatty acids and HDL cholesterol levels are associated with manifestations of atopy in adults (2003)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 33 (2003), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background The increase in allergic diseases is still unexplained. It was hypothesized that the intake of unsaturated fatty acids is a contributing cause of this development. We investigated the relationship between serum cholesterol levels, intake of polyunsaturated fatty acids (PUFA) and manifestations of atopy in a population-based setting.Methods A nested case–control study was performed within the population of the 3rd MONICA survey in Augsburg (Germany). The serum levels of total, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol of 1537 adults (aged 28–78 years, response 61.4%) and the estimated intake of PUFA in a subset of 139 men were compared with the frequency of a doctor's diagnosis of asthma, allergic rhinoconjunctivitis (AR), atopic eczema (AE) and allergic sensitization as measured by skin prick and Radio Allergo Sorbent Test.Findings In bivariate analyses, we obtained a negative linear association between total and LDL cholesterol levels and the frequency of AR and sensitization, which was no longer significant after adjustment for important confounders. In contrast, positive linear associations were found between HDL cholesterol levels and AR and AE and, furthermore, between the intake of PUFA and allergic sensitization in men (P〈0.01). After adjustment, an increasing risk for atopic diseases with increasing levels of HDL cholesterol and an increasing risk for allergic sensitization with increasing intakes of PUFA remained statistically significant.Interpretation There is indication that HDL cholesterol also plays a role in the complex interaction of fat intake, metabolism and the manifestation of atopy in adults. These findings may contribute to the understanding of time trends and regional differences of allergies.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2003.01780.x
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  • 3
    Electronic Resource
    Electronic Resource
    Inactivation of pepsin by high intensity ultraviolet light and the reciprocity law
    Amsterdam : Elsevier
    BBA - Biochimica et Biophysica Acta 9 (1952), S. 597-600 
    Details
    ISSN: 0006-3002
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Medicine , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-3002(52)90219-9
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Intracellular pH Is Insensitive to Changes in Intracellular Calcium Concentration in Isolated Rat Ventricular Myocytes (1996)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 779 (1996), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1996.tb44828.x
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  • 5
    Electronic Resource
    Electronic Resource
    Unterschiede im Ernährungsverhalten zwischen Wochenenden und Werktagen: Ergebnisse der Ernährungserhebung 1984/85 des MONICA-Projektes Augsburg (1991)
    Springer
    European journal of nutrition 30 (1991), S. 313-317 
    Details
    ISSN: 1436-6215
    Keywords: Ernährungserhebung ; Lebensmittelverzehr ; Nährstoffaufnahme ; Wochenende ; Werktage ; Dietary survey ; food intake ; nutrient intake ; weekend days ; weekdays
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Medicine
    Description / Table of Contents: Summary Seven-day food records of the MONICA project Augsburg dietary survey 1984/85 in 899 men aged 45–64 years were used to compare food and nutrient intake of weekdays and weekends. Differences were found in food intake. The mean intake of energy, macronutrients and especially alcohol was higher on weekends, whereas the dietary constituents independent of total energy intake, as percentage supply of energy from macronutrients, did not show huge differences.
    Notes: Zusammenfassung Anhand von 899 Sieben-Tage-Ernährungsprotokollen, die in der Ernährungserhebung 1984/85 des MONICA-Projektes Augsburg an Männern zwischen 45 und 64 Jahren erhoben wurden, wurden Unterschiede im Ernährungsverhalten zwischen Wochenenden und Werktagen untersucht. Es zeigten sich Unterschiede im Lebensmittelverzehr. Die mittlere Zufuhr an Energie und energieliefernden Nährstoffen, vor allem aber an Alkohol, war an Wochenenden deutlich höher als an Werktagen. In von der absoluten Energiezufuhr unabhängigen Variablen, wie z. B. dem prozentualen Anteil der Hauptnährstoffe an der Energiezufuhr, waren die Unterschiede wesentlich geringer.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01651961
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  • 6
    Electronic Resource
    Electronic Resource
    Endothelial cells are the major source of sICAM-1 in rheumatoid synovial tissue (1997)
    Springer
    Rheumatology international 17 (1997), S. 17-27 
    Details
    ISSN: 1437-160X
    Keywords: Key words Rheumatoid arthritis ; sICAM-1 ; Endothelial cells ; Synovial tissue
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of this research was to investigate the cellular source of soluble ICAM-1 (siCAM-1) from rheumatoid synovial tissue (RS) and its relation to sICAM-1 in synovial fluid (SF) and serum, and to study the expression of ICAM-1 in isolated cells of RS. sICAM-1 was determined by using the enzyme-linked immunosorbent assay (ELISA) and Western blot analysis in supernatants from RS cultured for short periods (n = 19), in SF (n = 7) and in serum (n = 19). ICAM-1 expression, vascularization and inflammatory infiltration (CD3, CD68, CD22) were characterized immunohistochemically in cytospin preparations (n = 18), cryosections (n = 18) and in conventionally stained paraffin sections (n = 19) of RS. The degree of RS vascularization was analysed morphometrically in immunohistochemically stained cryosections (factor VIII related antigen). We found 90-kD sICAM-1 in supernatants of cultured cells, in SF and in sera. sICAM-1 in cellular supernatant correlated significantly (P 〈 0.01) with SF sICAM-1. The amount of sICAM in cellular supernatants showed no correlation to the score of inflammatory infiltration, but correlated significantly (P 〈 0.001) with the vascularization index of RS. The percentage of ICAM-1-expressing cells correlated significantly (P 〈 0.001) with the percentage of CD68-positive macrophages, but not with CD3- and CD22-positive lymphocytes. Macrophages, multinucleated giant cells and endothelial cells exhibited a higher expression of ICAM-1 as compared to lymphocytes and fibroblasts. The differential expression of ICAM-1 on infiltrating leucocytes and resident cells of RS indicates a functional role of ICAM-1 in the local inflammatory process. SF sICAM-1 originated in RS, but serum sICAM-1 did not. Shedding of sICAM-1 by RS was independent of inflammatory infiltration, but depended on the degree of vascularization, indicating that endothelial cells are the major source of sICAM-1 in RS.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00006846
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  • 7
    Electronic Resource
    Electronic Resource
    Comparison of dietary intakes in four selected European populations (1992)
    Springer
    Journal of molecular medicine 70 (1992), S. 889-895 
    Details
    ISSN: 1432-1440
    Keywords: Epidemiologic study ; Nutritional survey ; Diet ; Dietary fat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The composition of diet and food intakes in four selected European populations were compared. Dietary data (from the World Health Organization Project on Monitoring Trends and Determinants in Cardiovascular Disease) were measured by record methods and were available for middle-aged men in Finland (n = 653), France (n =1128), Northern Ireland (n = 356), and southern Germany (Augsburg region; n = 899). Nutritional variables — which are independent of the absolute energy intake, such as the percentage supply of energy from macronutrients and the ratio of polyunsaturated to saturated fatty acids — were on the whole similar. However, striking differences were found in food intake and in the percentage supply of fat from different foods. The results indicate that detailed knowledge of consumption figures is necessary to develop prudent and acceptable nutrition intervention programs.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00180434
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  • 8
    Electronic Resource
    Electronic Resource
    Treatment of hypertension (1986)
    Springer
    Journal of molecular medicine 64 (1986), S. 1229-1236 
    Details
    ISSN: 1432-1440
    Keywords: High blood pressure ; Epidemiologic study ; Treatment ; Control ; Drug utilization ; Electrocardiogram
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In the Munich Blood Pressure Study (MBS), a cross-sectional study (MBS I) with follow-up (MBS II) of a random sample of 3,198 citizens aged 30–69 (response rate, 69.3%), treatment and control of hypertension were examined. Of the actual hypertensives 59% (221) in MBS II (373) were on drug treatment and about two-thirds (150) of those being treated had controlled blood pressure (BP). Women's BP was better controlled than men's. Of the 221 treated hypertensives 85% (188) received types of drugs or drug combinations which were in accordance with the recommendations of the German Hypertension League. However, this did not apply to the prescribed dosages of the various drugs. Of the treated hypertensives 52% were either on a diuretic, on a beta-blocker, or on a combination of both drugs. Rauwolfia alkaloids combined with a diuretic were given to 27%. In 79% of the participants who had received a beta-blocker either alone or in combination with other antihypertensive agents and who still had high BP values, the prescribed beta-blocker dosage was below the recommended daily dose. Fatigue was the most frequently reported symptom, possibly attributable to antihypertensive drug treatment. Electrocardiographic signs of left ventricular hypertrophy were found less frequently in controlled hypertensives, in comparison to treated but uncontrolled hypertensives or untreated hypertensives.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01734464
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  • 9
    Electronic Resource
    Electronic Resource
    Buchbesprechung (1991)
    Springer
    Journal of molecular medicine 69 (1991), S. 15-15 
    Details
    ISSN: 1432-1440
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01649049
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  • 10
    Electronic Resource
    Electronic Resource
    Die isolierte Zungenbeinfraktur (2000)
    Springer
    Der Unfallchirurg 103 (2000), S. 996-998 
    Details
    ISSN: 1433-044X
    Keywords: Schlüsselwörter Zungenbeinfraktur ; Diagnostik ; Therapie ; Keywords Hyoid bone fracture ; Diagnosis ; Therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract We present a rare case of isolated hyoid bone fracture caused by direct trauma. We will describe the mechanism of injury, how to find diagnosis and our treatment.
    Notes: Zusammenfassung Wir berichten über den seltenen Fall einer isolierten Zungenbeinfraktur bei einem Jugendlichen durch ein direktes Trauma. Erörtert werden Unfallmechanismus sowie Diagnostik und Therapie.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001130050658
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