Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Journal of agricultural and food chemistry 43 (1995), S. 1634-1637 
    ISSN: 1520-5118
    Source: ACS Legacy Archives
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Archives of microbiology 170 (1998), S. 427-434 
    ISSN: 1432-072X
    Keywords: Key words Acetogenesis ; Clostridium formicoaceticum ; Aromatic aldehydes ; Methoxylated aromatic ; compounds ; O-demethylation ; Cosubstrate metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract When the acetogen Clostridium formicoaceticum was cultivated on mixtures of aromatic compounds (e.g., 4-hydroxybenzaldehyde plus vanillate), the oxidation of aromatic aldehyde groups occurred more rapidly than did O-demethylation. Likewise, when fructose and 4-hydroxybenzaldehyde were simultaneously provided as growth substrates, fructose was utilized only after the aromatic aldehyde group was oxidized to the carboxyl level. Aromatic aldehyde oxidoreductase activity was constitutive (activities approximated 0.8 U mg–1), and when pulses of 4-hydroxybenzaldehyde were added during fructose-dependent growth, the rate at which fructose was utilized decreased until 4-hydroxybenzaldehyde was consumed. Although 4-hydroxybenzaldehyde inhibited the capacity of cells to metabolize fructose, lactate or gluconate were consumed simultaneously with 4-hydroxybenzaldehyde, and lactate or aromatic compounds lacking an aldehyde group were utilized concomitantly with fructose. These results demonstrate that (1) aromatic aldehydes can be utilized as cosubstrates and have negative effects on the homoacetogenic utilization of fructose by C. formicoaceticum, and (2) the consumption of certain substrates by this acetogen is not subject to catabolite repression by fructose.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 3
    ISSN: 1439-099X
    Keywords: Schlüsselwörter: Nichtinvasive Patientenfixierung ; Positionierungsgenauigkeit ; Extrakranielle Stereotaxie ; Intensitätsmodulierte Strahlentherapie ; IMRT ; Prostatakarzinom ; Key Words: Noninvasive patient immobilization ; Set-up accuracy ; Fractionated extracranial stereotactic radiotherapy ; IMRT ; Prostate tumors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Purpose: Highly conformal radiotherapy techniques require precise patient positioning. We report our first experience with a new cast system for fixation of the pelvis during stereotactically guided intensity modulated radiotherapy (IMRT) of the prostate with respect to positioning accuracy of the prostate. Material and Methods The immobilization device consists of a custom-made wrap-around body cast that extends from the abdomen to the thighs and a seperate head mask, both made from Scotchcast®, and attaches to a frame for extracranial stereotaxy. Sixteen CT-studies (≥ 25 slices, thickness: 3 mm) of 2 patients who were immobilized for IMRT of prostate tumors were evaluated with respect to set-up accuracy of bony structures and the prostate itself. CT-studies were performed immediately before or after a treatment fraction. Deviations of bony landmarks and anatomical landmarks inside the planning target volume were measured in all 3 dimensions. Results: Mean patient movements of 0.15 ± 0,3 mm (latero-lateral), 0,9 ± 1mm (anterior-posterior), 1 ± 1 mm (transversal vectorial error) and 〈 3 mm slice thickness (craniacaudal) were recorded using bony landmarks and 0,9 ± 0,9 mm (latero-lateral), 1,8 ± 1,5 mm (anterior-posterior), 2,2 ± 1,5 mm (transversal vectorial error) and 〈 3 mm (craniocaudal) using the confines of, or landmarks within the prostate. Standard deviations of absolute positioning error as an often used metric for positioning accuracy ranged between 0,3 and 1,7 mm in the transversal plane. The worst case transversal vectorial deviation for the prostate was 4,4 mm. Figure 4 summarizes the set-up accuracy of bony landmarks and the prostate. Conclusion The presented combination of a body cast and head mask system in a rigid stereotictic body frame ensures reliable noninvasive patient fixation for fractionated extrcranial stereotactic radiotherapy. It provides precise and reliable positioning of the prostate and meets the requirements for highly conformal radiotherapy such as IMRT. No further improvement of reprositioning can be achieved with external immobilization devices since the positioning error of the target relative to the skeleton exceeds the accuracy of the positioning of the skeleton itself.
    Notes: Hintergrund: Tumorkonforme Bestrahlungsverfahren erfordern die präzise, reproduzierbare Positionierung der Zielstrukturen. Wir stellen ein neues Fixierungssystem für die stereotaktisch geführte, intensitätsmodulierte Strahlentherapie (IMRT) im Beckenbereich im Hinblick auf die Positionierungsgenauigkeit der Prostata vor. Material und Methode: Das neue Fixierungssystem besteht aus einer umschließenden Körpermaske aus Scotchcast®, die vom Abdomen bis zu den distalen Abschnitten der Oberschenkel reicht, sowie einer Kopfmaske aus dem gleichen Material. Beide Masken sind fest mit einem Basissystem für die extrakranielle Stereotaxie verbunden. Zur Bestimmung der Lagerungspräzision wurden bei zwei Patienten insgesamt 16 CT-Untersuchungen (≥ 25 Schichten, 3 mm Schichtdicke) jeweils unmittelbar vor oder nach einer Bestrahlung mit Markierung des bestrahlten Isozentrums durchgeführt. Die Abweichungen von knöchernen Strukturen sowie von anatomischen Strukturen innerhalb des Zielvolumens wurden dann in allen drei Dimensionen gemessen. Ergebnisse: Mittlere Positionierungsfehler von 0,15 ± 0,3 mm (laterolateral), 0,9 ± 1mm (anterior-posterior), 1 ± 1mm (transversaler vektorieller Fehler) und 〈 3mm Schichtdicke (kraniokaudal) wurden unter Bezug auf knöcherne Orientierungspunkte ermittelt; während 0,9 ± 0,9 mm (laterolateral), 1,8 ± 1,5 mm (anterior-posterior), 2,2 ± 1,5 mm (transversaler vektorieller Fehler) und 〈 3mm (kraniokaudal) für die Abweichungen von Prostatabegrenzungen oder in der Prostata gelegenen Orientierungspunkten festgestellt wurden. Die häufig als Maßzahl für den Positionierungsfehler verwendete Standardabweichung der absoluten Patientenbewegung lag in der Transversalebene zwischen 0,3 und 1,7 mm. Die transversale vektorielle Maximalabweichung der Prostata lag bei 4,4 mm. Schlussfolgerung Das vorgestellte Fixierungssystem ermöglicht eine sehr genaue und zuverlässige Patientenpositionierung für die Behandlung von extrakraniellen Tumoren. Die präzise Patientenlagerung gewährleistet neben der stereotaktischen Bestrahlung von wirbelsäulennahen Tumoren auch die stereotaktische Bestrahlung in Beckenbereich. Da die Relativpositionierungsgenauigkeit der Zielstruktur gegenüber dem knöchernen Skelett variabler ist als die Positionsgenauigkeit des Skeletts, ist durch reine externe Immobilisierungsmaßnahmen keine weitere Verbesserung möglich.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...