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  • 1
    Electronic Resource
    Electronic Resource
    Management and outcome of obstructive uropathy in twin pregnancies (1993)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 100 (1993), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1993.tb14328.x
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  • 2
    Electronic Resource
    Electronic Resource
    Cord blood oxygen saturation in vigorous infants at birth: what is normal? (2000)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 107 (2000), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objective To define the normal ranges of umbilical cord blood oxygen saturation (SaO2) and acid-base status at birth and to evaluate the effect of gestational age on cord blood values in vigorous newborn infants following spontaneous vaginal birth from a vertex position.Design Prospective study.Setting Department of Obstetrics and Gynaecology, University of Graz, Austria.Sample Cord blood samples from 1281 vigorous newborn infants.Methods Cord blood sampling was performed following on newborn infants following spontaneous vaginal birth in a vertex position. SaO2 was measured directly by a spectrophotometer and pH, base excess, pCO2 and pO2 by a pH/blood-gas analyser. Infants with a 5-minute Apgar score ≥ 7 were considered vigorous. Subgroups were classified according to the gestational age: preterm, term and postterm (〈 37, 37–42 and 〉 42 weeks, respectively).Results The median umbilical artery SaO2 was 24.3% and the 2.5th centile was as low as 2.7%. The median umbilical artery values were pH = 7.25, base excess =−4.3 mmol/L and pO2= 16 mmHg. The 2.5th centiles were 7.08, −11.1 mmol/L and 5 mmHg, respectively. The median umbilical artery pCO2 was 50 mmHg and the 97.5th centile was 75 mmHg. The mean umbilical artery and vein SaO2 values were not significantly influenced by gestational age. The umbilical artery SaO2 and base excess values were strongly skewed. The mean umbilical artery pH values in preterm infants were higher than in other subgroups. The mean umbilical artery and vein base excess values were lower in post-term newborn infants than in other subgroups.Conclusions The physiological range of oxygen saturation in umbilical cord of vigorous newborn infants at birth is wide and skewed. In contrast to pH and base excess, umbilical cord blood oxygen saturation is not influenced significantly by gestational age at birth.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.2000.tb10401.x
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  • 3
    Electronic Resource
    Electronic Resource
    Zur Wirkung von Allylchlorid bei chronischer gewerblicher Exposition (1968)
    Springer
    Archives of toxicology 23 (1968), S. 209-214 
    Details
    ISSN: 1432-0738
    Keywords: Allylchloride ; Liver damage ; Liver functiontests ; Allylchlorid ; Leberschaden ; Leberfunktionsprüfung
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Bei der Erprobung einer neuen Technologie zur Herstellung von Allylchlorid waren 60 Personen für 16 Monate einer erhöhten Allylchlorid-Konzentration in der Raumluft ausgesetzt (MAK: 1 ppm). Die in der Literatur bei akuten Tierversuchen erhaltenen Ergebnisse deuten auf Nieren- und Leberschäden sowie auf Irritation der Schleimhäute hin. Die klinischen und labortechnischen Untersuchungen bei Allylchlorid exponierten Personen ergaben die Möglichkeit einer Leberschädigung. Speziell für die Leberdiagnostik wurden einige Enzyme im Serum bestimmt. Es wurden sowohl bei den mitochondrial als auch bei den cytoplasmatisch lokalisierten Enzymen Aktivitätsanstiege während der Exposition festgestellt. Bei Wiederholungsuntersuchungen an Personen, die aus diesem Betrieb herausgenommen wurden, konnte eine schnelle Normalisierung der Leberteste festgestellt werden.
    Notes: Summary During the test of a new technology for the manufacture of allylchloride 60 persons were exposed to increased allylchloride concentrations in the ambient air (MAK=1 ppm) for a duration of 16 months. Reports in the literature of acute animal tests indicate kidney- and liver damage as well as irritation of the mucosae. Clinical and laboratory examinations of persons exposed to low concentrations allylchloride showed that liver damage may occur. Especially for liver functiontest some enzyme activities in the serum were determined. In the course of the exposure an increase in activity was observed with both mitochondrially and cytoplasmatically localized enzymes. There is rapid normalisation of liver functiontests after stop of the work in this plant, as could be demonstrated by repeated reexamination.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00577397
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  • 4
    Electronic Resource
    Electronic Resource
    Zerebrale Blutflußgeschwindigkeit (Bfg) von Frühgeborenen〈1500 g unmittelbar postpartal (1993)
    Springer
    Archives of gynecology and obstetrics 254 (1993), S. 1598-1600 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02266550
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  • 5
    Electronic Resource
    Electronic Resource
    Amniotic fluid insulin levels in nondiabetic pregnant women: an update (1998)
    Springer
    Archives of gynecology and obstetrics 262 (1998), S. 81-86 
    Details
    ISSN: 1432-0711
    Keywords: Key words: Amniotic fluid insulin ; Normal range ; Nondiabetics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract. Elevated amniotic fluid insulin levels in diabetes are frequently described but there are few systematic data on metabolically healthy women to define normal ranges. Previous studies had too high normal ranges because they were based on unspecific insulin binding radioimmunoassays. The aim of the study was to update normal amniotic fluid insulin data and to define a reliable normal range in the course of a nondiabetic pregnancy. Amniotic fluid insulin levels were measured in 841 amniotic fluid samples of 707 nondiabetic women undergoing amniocentesis for hydramnios, suspected malformation, determination of lung maturation, Rhesus antibodies and cordocentesis. Mean (±SD) of amniotic fluid insulin level was 3.6 (±2.1) μU/mL at 31.5 (±4.9) weeks of pregnancy. The 97th percentile was 8.2 μU/mL. Insulin levels show a biphasic course between 16th and 42nd weeks of pregnancy with a zenith at 30th week. Only two cases (0.3%) had unexplicably elevated amniotic fluid insulin levels ≥10 μU/mL. Thus, in nondiabetic women amniotic fluid insulin levels 〉10 μU/mL are unlikely.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004040050232
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  • 6
    Electronic Resource
    Electronic Resource
    Cerebral blood flow velocities in the first minutes of life (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 269-270 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01956162
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  • 7
    Electronic Resource
    Electronic Resource
    Partial liquid ventilation with surfactant: effects on gas exchange and lung pathology in surfactant-depleted piglets (2000)
    Springer
    Intensive care medicine 26 (2000), S. 109-116 
    Details
    ISSN: 1432-1238
    Keywords: Key words Acute lung injury ; High frequency scillatory ventilation ; Histopathological lung injury score ; Partial liquid ventilation ; Perfluorocarbons ; Surfactant therapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To evaluate the effects of 24 h partial liquid ventilation (PLV) with and without surfactant (S) treatment on gas exchange and lung injury in a newborn animal model of S deficiency.¶Design: A prospective, controlled, in vivo animal laboratory study.¶Setting: Research laboratory in a university setting.¶Subjects: Twenty-four pathogen-free, male piglets (mean weight 1.9 kg, age 1–3 days).¶Interventions: The animals were randomised in four groups: PLV with FC-77 combined with conventional ventilation (PLV/CV) versus S + PLV/CV and PLV combined with high frequency oscillatory ventilation (PLV/HFOV) versus S + PLV/HFOV. The piglets were anaesthetised, intubated and instrumented with vascular catheters. Thirty minutes after lung injury had been induced with repeated saline lavage, S animals received natural S. Thirty minutes after surfactant substitution PLV with FC-77 was started. The oxygenation index (OI), PaO2/FIO2 ratio, PaCO2 and the ventilatory efficacy index were determined before and during PLV. After 24 h the lungs were removed for histopathological examination.¶Measurements and main results: Within 60 min after the initiation of PLV, all animals demonstrated improvements of the OI and PaO2/FIO2 ratio compared to the values after lung injury. However, at 18 and 24 h of PLV, the OI and PaO2/FIO2 ratio were significantly worse in the S + PLV/CV and S + PLV/HFOV groups compared to the groups without S. PaCO2 was higher at 18 and 24 h when S was used in PLV/HFOV (p 〈 0.05). A semi-quantitative lung injury score revealed most severe lung damage in the S + PLV/HFOV group.¶Conclusion: The combination of S and PLV with FC-77 led to an impaired gas exchange and did not further protect the animal from lung injury.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001340050022
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  • 8
    Electronic Resource
    Electronic Resource
    The clinical outcome after inferior vena cava thrombosis in early infancy (1999)
    Springer
    European journal of pediatrics 158 (1999), S. 416-420 
    Details
    ISSN: 1432-1076
    Keywords: Key words Factor V deficiency ; Infant ; Thrombosis ; Vena cava inferior
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The clinical outcome after inferior vena cava thrombosis in early infancy is unknown. We report the clinical long-term follow-up of 12 patients presenting inferior vena cava thrombosis within their first months of life (gestational age: 24–41 weeks; follow-up: 7±3 years). Accompanying renal venous thrombosis occurred in 9, and adrenal bleeding in 4 patients. A central venous catheter was related to the thrombosis in only four patients. Heterozygous factor V Leiden mutation was found in two of the eight infants without central venous catheter. Thrombolysis was performed in seven and effective in three infants; one infant required surgical thrombectomy. In three of eight infants with ineffective or with no therapy, spontaneous recanalization occurred during follow-up. No patient died of the thrombosis. Although no long-term anticoagulatory prophylaxis was performed, none of the children with persisting occlusion (n=5) or stenosis (n=1) of the inferior vena cava developed symptomatic thrombo-embolic complications. However, extensive internal collaterals (n=6), visible varicosis (n=5), pain in the legs (n=3) and persisting renal disease (n=3) with arterial hypertension (n=2) were observed during follow-up. Conclusion Inferior vena cava thrombosis of early infancy frequently persists and may cause considerable long-term morbidity. New strategies for early and long-term therapy are necessary.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004310051105
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  • 9
    Electronic Resource
    Electronic Resource
    Dangers of countercurrent use in swimming-pools (1999)
    Springer
    European journal of pediatrics 158 (1999), S. A267 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00008322
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  • 10
    Electronic Resource
    Electronic Resource
    Die Risiken des Gestationsdiabetes (1989)
    Springer
    Archives of gynecology and obstetrics 245 (1989), S. 278-279 
    Details
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02417273
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