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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    World journal of surgery 7 (1983), S. 385-389 
    ISSN: 1432-2323
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Résumé Les modifications de la concentration dans le plasma de la catécholamine et de la gastrine ainsi que les modifications de la secrétion d'acide gastrique après repas d'épreuve simulé ont été étudiées chez 7 malades atteints d'ulcère duodénal avant la vagotomie hypersélective et 6 semaines après celle-ci. La sécrétion basale et le pic de la sécrétion acide furent réduits après la vagotomie hypersélective. Les concentrations de la noradrénaline plasmatique qui étaient élevées chez les ulcéreux revirent à la normale après l'intervention. En revanche, les taux de l'adrénaline plasmatique qui étaient voisins de la normale avant l'intervention ne varièrent pas après celle-ci. Les taux de la gastrine plasmatique furent sensiblement plus élevés après la vagotomie hypersélective. Cette étude permet d'affirmer que le repas d'épreuve simulée ne produit pas de modification significative des taux de la catécholamine et de la gastrine plasmatique avant ou après vagotomie hypersélective, mais, en revanche, l'intervention est suivie de la diminution du taux de la noradrénaline. On peut conclure de l'ensemble de ces faits que la noradrénaline est impliquée dans la genèse de la maladie ulcéreuse ou qu'elle en constitue le reflet.
    Abstract: Abstracto Los cambios en las concentraciones plasmáticas de catecolamina y de gastrina y en la secreción de ácido gástrico en respuesta a una comida fantasma (sham feeding), fueron investigados en 7 pacientes con Úlcera duodenal (DU) antes y 6 semanas después de vagotomía altamente selectiva (HSV). Tanto la secreción basal como la secreción pico en respuesta a una comida fantasma modificada, fueron reducidas en forma significativa por la HSV. Las concentraciones plasmáticas de noradrenalina se encontraban elevadas en pacientes con UD, pero descendieron a valores normales después de HSV. Las concentraciones plasmáticas de adrenalina estuvieron dentro de límites normales y no cambiaron después de HSV. Las concentraciones basales de gastrina se hallaron significativamente más altas después de HSV que antes. La comida fantasma modificada no causó cambios significativos en las concentraciones plasmáticas de catecolamina y de gastrina, ni pre ni postoperatoriamente. Se concluye que la noradrenalina está involucrada en, o es un reflejo de la enfermedad ulcerosa duodenal.
    Notes: Abstract The changes in plasma catecholamine and gastrin concentrations and gastric acid secretion in response to modified sham feeding were investigated in 7 duodenal ulcer (DU) patients before and 6 weeks after highly selective vagotomy (HSV). Both basal and peak acid secretion in response to modified sham feeding were significantly reduced by HSV. Basal plasma noradrenaline concentrations were elevated in DU patients but fell to normal values after HSV. Plasma adrenaline concentrations were within the normal range and did not change after HSV. Basal gastrin concentrations were significantly higher after HSV than before. Modified sham feeding caused no significant changes in plasma catecholamine and gastrin concentrations either pre- or postoperatively. It is concluded that noradrenaline is involved in, or reflects, DU disease.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Urological research 14 (1986), S. 323-325 
    ISSN: 1434-0879
    Keywords: Persistent hypercalcemia ; Parathyroid adenoma ; Preoperative localization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A retrospective analysis of 34 patients undergoing 45 re-explorations for persistent hypercalcemia is presented. Thirteen out of the 20 enlarged parathyroid glands were found at reoperation to be normally located, indicating that the initial exploration had been incomplete. A follow-up study of the reoperated patients showed that 25 (74%) were normocalcaemic. Three patients had permanent unilateral recurrent laryngeal nerve damage and 2 patients required calcium and/or vitamin D therapy. Ultrasonography was effective in the diagnosis and localisation of residual parathyroid adenoma in patients with persistent postoperative hyperparathyroidism.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 33 (1977), S. 236-237 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The influence from carotid baroreceptors on portal immuno-reactive glucagon and insulin levels and on arterial plasma glucose concentration was studied in vagotomized cats by sectioning of the sinus nerves. Such a complete elimination of the afferent baroreceptor discharge caused a prompt and pronounced increase in the glucose and glucagon levels, whereas the insulin concentration significantly decreased. The role of vascular baroreceptors in the hyperglycemic response to hemorrhage is discussed.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-2568
    Keywords: catecholamines ; duodenal ulcer ; gastric acid ; G-1 hormones ; noradrenaline ; sympathoadrenal system
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract It is not known if the increased plasma concentration of noradrenaline in patients with chronic duodenal ulcer disease is a pathogenetic factor or not. The aim of the present study was to investigate if physiologic changes of noradrenaline would evoke any alterations in gastric acid secretion or in the plasma concentration of some gastrointestinal hormones (gastrin, secretin, PP, PYY, and GIP) known to affect gastric physiology. The results show that basal plasma noradrenaline concentration was 1.8 nM and after infusion with noradrenaline at 0.04 or 0.2 nmol/kg/min plasma levels of 2.5 and 4.4 nM were obtained. No appreciable changes could be found in basal or pentagastrin stimulated acid secretion or in any of the gastrointestinal peptides studied. If the elevated plasma noradrenaline concentration observed in duodenal ulcer patients is a pathogenetic factor; it is probable that it interferes with other variables such as blood flow, bicarbonate secretion, or prostaglandin synthesis.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Cell & tissue research 221 (1982), S. 617-624 
    ISSN: 1432-0878
    Keywords: Vasoactive intestinal polypeptide (VIP) ; Peptidergic nerves ; Portalvein ; Vascular effects
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary Nerve fibres displaying immunoreactivity for vasoactive intestinal polypeptide (VIP) were found in the wall of the portal vein in cats, guinea pigs, rats and mice. In whole-mount preparations a sparse network of VIP fibres was seen in the vessel wall. Electrical field stimulation of the rat portal vein in vitro caused a significant release of VIP. The results suggest that VIP ergic nerve fibres play a role in the regulation of portal blood flow.
    Type of Medium: Electronic Resource
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