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  • 1
    Electronic Resource
    Electronic Resource
    Harman and norharman plasma levels in weaned alcoholics: correlations with depression and tobacco smoking (2000)
    Oxford, UK : Blackwell Publishing Ltd
    Addiction biology 5 (2000), S. 0 
    Details
    ISSN: 1369-1600
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Based on the hypothesis that β-carbolines are involved in the pathogenesis of alcohol-related mood disturbance, harman and norharman levels were assayed in the blood plasma of alcoholics and correlated to the Hamilton Depression (HAM-D) scores after 3 and 5 weeks post-admission. Tobacco smoking was co-evaluated since it is known to influence β-carboline levels. After a 3-week period, plasma harman but not norharman was increased in depressed alcoholics and positively related to the HAM-D sum-score (r = 0.47; p 〈 0.04) and to tobacco smoking (r = 0.56; p 〈 0.02). Since no correlation between depression and smoking was found, these data could account for the higher incidence of depressive symptoms in withdrawn alcoholics with increased harman levels. The partial correlations support this hypothesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1369-1600.2000.tb00213.x
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  • 2
    Electronic Resource
    Electronic Resource
    Surgical treatment of acromioclavicular dislocation (1994)
    Springer
    Archives of orthopaedic and trauma surgery 113 (1994), S. 308-311 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Sixty-five patients were operated on for acromioclavicular dislocation between 1980 and 1991. Seventeen type II and 48 type III dislocations according to the criteria of Tossy et al. [15] were treated. Three different surgical techniques were employed. (1) tension band wiring, (2) a modification of the Bosworth repair [3], (3) reconstruction of the ligaments with augmentation by a PDS (polydioxanon) cord. Forty-four patients could be investigated retrospectively, and an additional 12 were recorded by questionnaire. The Taft score [14] was used, representing self-assessment, clinical statements and radiological findings. Of all investigated patients 87.5% had a normal range of motion without any loss of strength, and 32% suffered an osteoarthritis of the acromioclavicular joint. The average Taft score was 9.8. With respect to the three surgical techniques, reconstruction of the ligaments augmented by a PDS cord produced the best result, an average Taft score of 10.8.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00426177
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  • 3
    Electronic Resource
    Electronic Resource
    The importance of functional magnetic resonance imaging (MRI) in the planning of stabilizing operations on the cervical spine in rheumatoid patients (1989)
    Springer
    Archives of orthopaedic and trauma surgery 109 (1989), S. 30-33 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Chronic inflammatory diseases, such as chronic polyarthritis or spondylarthritis ankylopoietica, can occasionally lead to vertebral instabilities of the occipitoatlantal or atlantoaxial level, requiring some form of stabilizing operation. By means of functional magnetic resonance imaging, i.e., with the cervical spine at its maximal range of flexion and extension, performed on 11 patients suffering from an instability at the above level, it was possible to demonstrate not only the extent of synovial tissue, but also how this sometimes excessive soft-tissue growth hinders an adequate reduction of the subluxated vertebrae. The importance of this investigation lies in the fact that the necessary operation can be planned appropriately. As such, three patients required a decompressing operation entailing resection of the posterior arch of the atlas, widening of the foramen magnum, or both.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00441906
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  • 4
    Electronic Resource
    Electronic Resource
    Rapidly progredient scoliosis associated with multicore disease (1998)
    Springer
    Archives of orthopaedic and trauma surgery 117 (1998), S. 411-414 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Multicore disease is a rare congenital myopathy that normally stops or makes slow progress. It starts with delayed motor development and frequent falls. Especially the proximal muscles are invovled. Other symptoms include contractures of joints, clubfoot, high arched palate, chest deformities, involvement of eye-muscle, cardiac abnormalities, hyperlordosis and scoliosis that normally does not require surgery. We report a rare case of advanced scoliosis in multicore disease requiring operative treatment in a 15-year-old girl. In this case the scoliosis took a rapidly progredient course in puberty close to the end of skeletal growth. A dorsal spondylodesis with USS instrumentation from T9 to L3 was performed. A significant reduction of the scoliosis was obtained. Scoliosis in multicore disease may take a rapidly progredient course. Frequent checks will lead to the initiation of surgical treatment in time.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s004020050282
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  • 5
    Electronic Resource
    Electronic Resource
    Operative therapy for recurrent shoulder dislocation with special regard to long-term clinical and radiological results using M. Lange technique (1989)
    Springer
    Archives of orthopaedic and trauma surgery 108 (1989), S. 107-111 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Besides a general description of the operative techniques for the management of recurrent shoulder dislocation, a full description of the M. Lange procedure is given. We offer reasons for its variation from original methods and suggest limiting its indications with regard to clinical and radiological long-term results. After an average postoperative period of 13.5 years, clinical and radiological results of 21 shoulders in 20 patients were determined. In 19 of the 21 cases patients reported outstanding-to-satisfying postoperative results. Real postoperative redislocation was found in only one case, but striking radiological signs of osteoarthritis were seen in 57%. Despite the lack of comparable results, this should be taken into consideration in choosing an adequate operative procedure.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00932166
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  • 6
    Electronic Resource
    Electronic Resource
    Examinations of the pathology of the rotator cuff (1987)
    Springer
    Archives of orthopaedic and trauma surgery 106 (1987), S. 301-308 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Zur Überprüfung der in der Literatur geäußerten unterschiedlichen Auffassungen zur Pathogenese und Häufigkeit der Tendinopathia calcarea und der Rotatorenmanschettenruptur wurden eigene autoptische Untersuchungen an 195 Schultergelenken durchgeführt. Es zeigte sich eine Rupturhäufigkeit von 11%. Intratendinöse Verkalkungen zeigten sich röntgenologisch in 22% der Fälle. Das gleichzeitige Vorliegen von intratendinbsen Verkalkungen und Rotatorenmanschettenrupturen konnte in 13 von 22 Fällen mit Vorliegen einer Rotatorenmanschettenruptur nachgewiesen werden. Aufgrund der Ergebnisse unserer Untersuchung ist von einer identischen Pathogenese der Tendinopathia calcarea und der Rotatorenmanschettenruptur auszugehen.
    Notes: Summary We performed autopsies on 195 shoulder joints in order to check the differing opinions as to the pathogenesis and incidence of tendinopathia calcarea and rupture of the rotator cuff that have been expressed in literature. There was a rupture rate of 11%. Intratendinous calcific deposits could be observed by radiology in 22% of the cases. The simultaneous presence of intratendinous calcification and rotator cuff rupture could be proved in 13 of 22 cases with a rupture of the rotator,cuff. On the basis of our results we conclude that tendinopathia calcarea and rupture of the rotator cuff have an identical pathogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00454338
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  • 7
    Electronic Resource
    Electronic Resource
    Destructive changes of the spine in magnetic resonance imaging (1990)
    Springer
    Archives of orthopaedic and trauma surgery 109 (1990), S. 133-138 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twenty-nine patients were examined by magnetic resonance imaging for various lesions of the spine. The results of these scans were compared with those of plain radiographs, computertomographs, and radionuclide bone scans. The findings were substantiated by intraoperative or histological findings in 18 cases. The MRI scans proved to be very sensitive in the detection of a wide spectrum of morphological changes of the bone marrow of vertebral bodies. Characteristic changes of the signal patterns for inflammatory and tumorous lesions were not observed. The differentiation of these lesions will presently continue to have to be based on morphological criteria.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00440573
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  • 8
    Electronic Resource
    Electronic Resource
    Indications for and results of operative treatment of spondylitis and spondylodiscitis (1991)
    Springer
    Archives of orthopaedic and trauma surgery 110 (1991), S. 78-82 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We present a retrospective follow-up study of 24 patients with spondylitis or spondylodiscitis whose treatment included surgical intervention. Tuberculous spondylitis was diagnosed in 14 patients and 10 suffered from non-specific spondylitis. The average age of the patients was 50.2 years and average follow-up was 3 years. All patients were asymptomatic at the time of examination and showed radiographic evidence of solid fusion. We recommend radical debridement and spinal fusion through a ventral approach in patients with destruction of the ventral vertebral body, progressive neurological impairment, septicaemia and antibiotic-resistant, symptomatic infections of the spine. In the elderly patient, even in reduced states of health, early surgical intervention can be particularly valuable. Although surgical intervention should be reserved for specific indications, we were able to document favourable results in all 24 patients treated with debridement and spinal fusion.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00393878
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  • 9
    Electronic Resource
    Electronic Resource
    Role of internal and external fixation in ankle fusion (1996)
    Springer
    Archives of orthopaedic and trauma surgery 115 (1996), S. 146-148 
    Details
    ISSN: 1434-3916
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Between August 1980 and September 1993, 35 tibiotalar arthrodeses in 34 patients with primary and secondary osteoarthritis of the ankle were performed. Two different surgical techniques were employed. Internal screw fixation according to Wagner and Pock [20] and an external fixation method ccording to the resection compression arthrodesis by Charnley and Müller [14]. Twenty patients with 21 fusions could be investigated retrospectively. For evaluation we used self-assessment, clinical examination and radiographic analysis in combination with the score described by McGuire et al. [12]. In 80% the results were good and satisfactory with a median improvement of 23 score points on a scale of 100% 95 points, respectively. The most important advantages were pain relief and increase of walking distance. The fusion rate was 95%. We found osteoarthritis in the neighbouring joints did not have any influence on the surgical result. With respect to the two surgical techniques, the internal screw fixation method achieved fusion earlier with fewer complications and better improvement according to the McGuire score. Tibiotalar fusion is a safe therapy with reproducible good results involving pain relief, full weight-bearing and increase of walking distance.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00434542
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  • 10
    Electronic Resource
    Electronic Resource
    Vermeidbarkeit von Fremdblut trotz extremen Blutverlustes (1997)
    Springer
    Der Anaesthesist 46 (1997), S. 964-968 
    Details
    ISSN: 1432-055X
    Keywords: Schlüsselwörter Hämodilution ; Allogene Transfusion ; Fremdblutsparende Maßnahmen ; Anämie ; Hyperoxische Beatmung ; Key words Hemodilution ; Allogeneic blood transfusion ; Blood-saving methods ; Anemia ; Hyperoxic ventilation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract We report the case of a 22-year-old woman who underwent two-step scoliosis surgery without allogeneic transfusion, although the intraoperative blood loss (3500 ml) during the first procedure was higher than the calculated blood volume (3250 ml). Preoperatively the patient had donated four units of autologous blood. Intraoperatively blood-saving methods were combined. During the first operation acute normovolemic hemodilution (target hemoglobin 9.0 g/dl) was applied and during the second operation controlled hypotension (systolic blood pressure 80 mmHg). Intraoperative autotransfusion was used in both procedures. During the first operation severe normovolemic anemia (minimal hemoglobin 3.5 g/dl) was accepted while the patient was ventilated with FiO2 1.0. The hemoglobin concentration was 8.6 g/dl after the first procedure and had increased to 11.6 g/dl 4 weeks after the second procedure. No severe complications occurred during the postoperative phase. This case report shows that also in surgical procedures with extreme blood loss any allogeneic transfusion can be avoided by the combination of blood-saving methods, acceptance of low intraoperative transfusion trigger and ventilation with 100% oxygen.
    Notes: Zusammenfassung Der vorliegende Fallbericht beschreibt, wie bei einer 22jährigen Patientin während einer zweizeitigen Respondylodeseoperation jegliche allogene Transfusion vermieden werden konnte, obwohl der Gesamtblutverlust (3500 ml) beim Ersteingriff das berechnete Blutvolumen (3250 ml) überstieg. Präoperativ hatte die Patientin 4 Eigenblutkonserven gespendet. Intraoperativ wurden fremdblutsparende Techniken kombiniert: während des Ersteingriffs wurden eine präoperative normovolämische Hämodilution (Zielhämoglobinkonzentration 9,0 g/dl), während des Zweiteingriffs eine kontrollierte Hypotension (systolischer Blutdruck 80 mmHg) durchgeführt, bei beiden Eingriffen wurde außerdem intraoperativ ein Cell-Saver eingesetzt. Im Rahmen der akuten normovolämischen Hämodilution (ANH) wurde beim Ersteingriff eine ausgeprägte, normovolämische Anämie (minimale Hämoglobinkonzentration 3,5 g/dl) während Beatmung mit einer FiO2 von 1,0 akzeptiert. Nach dem Ersteingriff betrug die Hämoglobinkonzentration 8,6 g/dl und war 4 Wochen nach dem Zweiteingriff auf 11,6 g/dl angestiegen. Der postoperative Verlauf war nach beiden Eingriffen komplikationslos. Dieser Fall zeigt, daß durch die Akzeptanz und Kombination von fremdblutsparenden Techniken, niedriger intraoperativer Transfusionstrigger und Beatmung mit reinem Sauerstoff elektive Eingriffe mit extremem Blutverlust ohne allogene Transfusionen durchgeführt werden können.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s001010050493
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