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  • 1
    Electronic Resource
    Electronic Resource
    Helicobacter pylori eradication is superior to ulcer healing with or without maintenance therapy to prevent further ulcer haemorrhage (2001)
    Oxford UK : Blackwell Science Ltd
    Alimentary pharmacology & therapeutics 15 (2001), S. 0 
    Details
    ISSN: 1365-2036
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Helicobacter pylori eradication decreases ulcer recurrence and should prevent recurrent ulcer haemorrhage.〈section xml:id="abs1-2"〉〈title type="main"〉Aim:By meta-analysis, to compare treatment of H. pylori infection with other approaches to prevent recurrent ulcer haemorrhage and, by cost minimization analysis, to determine the least costly strategy.〈section xml:id="abs1-3"〉〈title type="main"〉Methods:We searched for randomized, controlled trials comparing treatment of H. pylori infection with ulcer healing alone or with maintenance therapy in preventing recurrent ulcer haemorrhage. We calculated the relative and absolute risk reductions and numbers needed to treat.〈section xml:id="abs1-4"〉〈title type="main"〉Results:Treatment of H. pylori infection decreased recurrent bleeding by 17% (numbers needed to treat=6) compared with ulcer healing treatment alone. Compared with ulcer healing treatment followed by maintenance therapy, recurrent bleeding was decreased by 4% (numbers needed to treat=25). Decision model-based cost minimization analysis demonstrated that treatment of H. pylori infection was the least costly strategy unless the incidence of complicated recurrences after treatment was over 6%, or the cost of confirming eradication was over $741.〈section xml:id="abs1-5"〉〈title type="main"〉Conclusions:Treatment of H. pylori infection is superior to ulcer healing treatment with or without maintenance therapy in preventing recurrent ulcer haemorrhage. All patients with ulcer bleeding should be tested for H. pylori infection and appropriately treated if positive.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2036.2001.01134.x
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  • 2
    Electronic Resource
    Electronic Resource
    Activation of calcium and phospholipid-dependent protein kinase by epidermal growth factor (EGF) in A431 cells: Attenuation by 12-0-tetradecanoylphorbol-13-acetate (TPA)
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 109 (1982), S. 1206-1214 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-291X(82)91905-2
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  • 3
    Electronic Resource
    Electronic Resource
    Lack of response of (Ca^2^++Mg^2^+) ATPase to atrial natriuretic peptide in basolateral membranes from kidney cortex of chronic diabetic rats
    Amsterdam : Elsevier
    Biochemical and Biophysical Research Communications 169 (1990), S. 537-544 
    Details
    ISSN: 0006-291X
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology , Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1016/0006-291X(90)90364-S
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  • 4
    Electronic Resource
    Electronic Resource
    Modulation of type-IV procollagen and laminin production in A431 human squamous epidermoid carcinoma cells by 12-O-tetradecanoylphorbol-13-acetate (TPA) and epidermal growth factor (EGF) (1985)
    Springer
    Archives of dermatological research 277 (1985), S. 377-383 
    Details
    ISSN: 1432-069X
    Keywords: Type-IV procollagen ; Laminin ; EGF ; TPA
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The effect of 12-O-tetradecanoylphorbol-13-acetate (TPA) and epidermal growth factor (EGF) on type-IV-procollagen (basement-membrane collagen) and laminin synthesis, turnover, and secretion was studied in human A431 squamous epidermoid carcinoma cells. Type-IV procollagen and laminin were biochemically and immunologically identified in the medium and cell extracts using immunoprecipitation followed by sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis. EGF or TPA produced a sixfold increase in type-IV-procollagen and laminin secretion within 2 h; this was accompanied by a three-to fourfold increase in the levels of cell-associated type-IV procollagen and laminin, respectively. The level of type-IV-procollagen and laminin synthesis and secretion remained elevated for at least 16 h after the administration of either EGF or TPA. A combination of EGF and TPA was more effective than either agent alone in promoting the secretion of laminin but not of type-IV procollagen. EGF and/or TPA did not, however, produce a selective increase in the synthesis of collagen and laminin, since total protein synthesis was also increased to the same degree by these agents. As dtermined by labeling and chase studies, neither EGF nor TPA had any appreciable effect upon type-IV-procollagen or laminin degradation. These results indicate that the synthesis of components associated with the basement membrane in A431 cells (i.e., type-IV procollagen and laminin) can be rapidly modulated by EGF and a tumor promoter, i. e., TPA. The increase in extracellular-matrix-protein production precedes any effects of these agents on cell growth. However, changes in cell shape in response to either EGF or TPA may trigger the increase in the synthesis and secretion of type-IV procollagen and laminin.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00509237
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  • 5
    Electronic Resource
    Electronic Resource
    Pushing Disks Together—The Continuous-Motion Case (1998)
    Springer
    Discrete & computational geometry 20 (1998), S. 499-514 
    Details
    ISSN: 1432-0444
    Source: Springer Online Journal Archives 1860-2000
    Topics: Computer Science , Mathematics
    Notes: Abstract. If disks are moved so that each center—center distance does not increase, must the area of their union also be nonincreasing? We show that the answer is yes, assuming that there is a continuous motion such that each center—center distance is a nonincreasing function of time. This generalizes a previous result on unit disks. Our proof relies on a recent construction of Edelsbrunner and on new isoperimetric inequalities of independent interest. We go on to show analogous results for the intersection and for holes between disks.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/PL00009398
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  • 6
    Electronic Resource
    Electronic Resource
    All India summer monsoon rainfall prediction using an artificial neural network (2000)
    Springer
    Climate dynamics 16 (2000), S. 291-302 
    Details
    ISSN: 1432-0894
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences , Physics
    Notes: Abstract The prediction of Indian summer monsoon rainfall (ISMR) on a seasonal time scales has been attempted by various research groups using different techniques including artificial neural networks. The prediction of ISMR on monthly and seasonal time scales is not only scientifically challenging but is also important for planning and devising agricultural strategies. This article describes the artificial neural network (ANN) technique with error- back-propagation algorithm to provide prediction (hindcast) of ISMR on monthly and seasonal time scales. The ANN technique is applied to the five time series of June, July, August, September monthly means and seasonal mean (June + July + August + September) rainfall from 1871 to 1994 based on Parthasarathy data set. The previous five years values from all the five time-series were used to train the ANN to predict for the next year. The details of the models used are discussed. Various statistics are calculated to examine the performance of the models and it is found that the models could be used as a forecasting tool on seasonal and monthly time scales. It is observed by various researchers that with the passage of time the relationships between various predictors and Indian monsoon are changing, leading to changes in monsoon predictability. This issue is discussed and it is found that the monsoon system inherently has a decadal scale variation in predictability.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s003820050328
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  • 7
    Electronic Resource
    Electronic Resource
    Traumatic aneurysm of superficial temporal artery (1991)
    Springer
    Neuroradiology 33 (1991), S. 510-512 
    Details
    ISSN: 1432-1920
    Keywords: Aneurysm-traumatic ; Carotid angiography ; Computed tomography ; Head injury ; Superficial temporal artery
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A case of traumatic pseudo-aneurysm of the superficial temporal artery documented on Computed tomography (CT) and angiography is described in a 55-years-old female, who was treated by surgical excision. Computed tomographic appearance of this lesion is illustrated. This represents, to our knowledge, the first CT demonstration of traumatic aneurysm of superficial temporal artery within a large subgaleal haematoma.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00588042
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  • 8
    Electronic Resource
    Electronic Resource
    Observations on atrial natriuretic peptide, sympathetic activity and renal Ca2+ pump in diabetic and hypertensive rats (1993)
    Springer
    Clinical autonomic research 3 (1993), S. 137-143 
    Details
    ISSN: 1619-1560
    Keywords: Renal Ca2+ pump ; ANP ; Sympathetic system ; Diabetes with hypertension
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The relationship between atrial natriuretic peptide (ANP) and peripheral sympathetic nervous system function was studied in diabetic and hypertensive rats. Animals were divided into four groups: control, diabetic, hypertensive and diabetic plus hypertensive. Diabetes was induced by streptozotocin (65 mg/kg) injection and hypertension by abdominal aortic constriction. Studies were performed at 1 and 6 weeks. Plasma ANP was increased at 1 week in all groups except controls. Noradrenaline turnover, an index of sympathetic activity in kidney, was attenuated in all pathological groups unlike controls. These changes were associated with increased activity of Ca2+ + Mg2+ ATPase, which is known to serve as a Ca2+ pump in kidney cortex basolateral membrane. In contrast, at 6 weeks, Ca2+ + Mg2+ ATPase was significantly decreased only in the diabetic plus hypertensive group which also showed signs of congestive heart failure, increased sympathetic activity and decreased plasma ANP levels. Intracerebral microdialysis of the extracellular space around the paraventricular nucleus (PVN) of the hypothalamus showed a decreased concentration of ANP in the diabetic plus hypertensive group. Infusion of ANP and pentolinium, a ganglionic blocker in diabetic plus hypertensive Ca2+ restored pump activity towards control values; ANP alone had no effect. Our results indicate decreased plasma ANP levels, increased sympathetic drive and a depressed kidney Ca2+ pump in diabetic plus hypertensive rats with heart failure. The relationships between these factors, and the potential modulating role of ANP is discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01818999
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  • 9
    Electronic Resource
    Electronic Resource
    An efficient estimator using auxiliary information (1980)
    Springer
    Metrika 27 (1980), S. 271-275 
    Details
    ISSN: 1435-926X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mathematics
    Notes: Abstract The use of ratio and product methods of estimation using auxiliary information for estimating the mean of a finite population is well known.Srivastava [1967] andReddy [1973] proposed ratio-cum-product type estimators. This paper proposes a transformed estimator which is even more efficient than these estimators for a wide range of the value of the correlation coefficient between the main and auxiliary variables.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01893605
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  • 10
    Electronic Resource
    Electronic Resource
    Transient healing of TIPS-induced biliovenous fistula by PTFE-covered stent graft (1996)
    Springer
    Digestive diseases and sciences 41 (1996), S. 2229-2232 
    Details
    ISSN: 1573-2568
    Keywords: covered stent ; transjugular intrahepatic portosystemic shunt ; bilhemia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02071405
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