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  • 1
    ISSN: 1432-1335
    Keywords: Osteosarcoma ; Chemotherapy ; Electronmicroscopy ; Histochemistry ; Autoradiography
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Twelve osteosarcomas treated according to the COSS 80 protocol (preoperative chemotherapy, resection) were studied by light and electron microscopic, histochemical, and autoradiographic methods. Evidence of regressive and necrotic changes was found in many tumor cells, but the alterations were unspecific. Viable tumor cells of high malignancy were also observed regularly, often at the S phase. As the tumor regression continued, a strong reaction of the mononuclear phagocyte system was manifested by the presence of macrophages and giant cells.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 297 (1961), S. 147-159 
    ISSN: 1435-2451
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung Synovialome sindmaligne Tumoren, die von der Synovialis eines Gelenkes, von einem Schleimbeutel oder von einer Sehnenscheide ausgehen können. Es wird über 2 histologisch und klinisch gesicherte Synovialome von seltener Lokalisation berichtet und an Hand des Weltschrifttums ausführlich auf die Histogenese, Histologie, Klinik und Therapie dieser Tumoren eingegangen. Eine Besserung der Prognose ist nur von einer frühzeitigen Radikaloperation zu erwarten.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Langenbeck's archives of surgery 348 (1979), S. 133-139 
    ISSN: 1435-2451
    Keywords: Colorectal carcinomas ; Radiotherapy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Eine Indikation zur Strahlentherapie des colorectalen Carcinoms ist nach unserer Meinung immer gegeben: 1. Operable Carcinome sollten vorbestrahlt werden, eine postoperative Aufsättigung der ≪high-risk≫ Fälle auf volle Tumordosis würden wir empfehlen. 2. Inoperable oder subtotal operierte Carcinome sollten einer Strahlentherapie mit tumoricider Dosis unterworfen werden. 3. Das Lokalrezidiv — in Besonderheit das Beckenbodenrezidiv —ist auch wegen der häufig fehlenden operativen Eingreifmöglichkeiten eine Indikation zur Strahlentherapie. Die notwendige Dosis muß eine evtl. Vorbelastung berücksichtigen. 4. Die ausgezeichneten Palliativeffekte einer Strahlentherapie begründen ihre Anwendung von selbst.
    Notes: Summary The authors are of the opinion that radiotherapy is always indicated for colorectal carcinoma patients: (1)Operable carcinomas should be given radiation treatment before operation; postoperative saturation of high-risk cases at the full tumor dose is recommended. (2) Inoperable or partially operated carcinomas should be treated with tumoricidal radiation dose. (3) Radiotherapy is also indicated for cases of local recurrence, especially in the floor of the pelvis, in view of the frequent lack of possible operative access. The necessary dose rate must take into account any prior radiation load. (4) The excellent palliative results are themselves a recommendation for radiotherapy.
    Type of Medium: Electronic Resource
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