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  • 1
    Electronic Resource
    Electronic Resource
    Cytokine pattern in allergic and non-allergic chronic rhinosinusitis in asthmatic children (2002)
    Oxford, UK : Blackwell Science, Ltd
    Clinical & experimental allergy 32 (2002), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Rhinosinusitis represents one of the most common chronic diseases. The association of rhinosinusitis with asthma has been frequently reported. Eosinophils and Th2 cells play a pathogenic mechanism in asthma.Objective The aims of the study were to evaluate the cytokine pattern in chronic rhinosinusitis in asthmatic children and to compare the findings in allergic vs. non-allergic asthmatics.Methods Thirty-five asthmatic children were evaluated, 19 males and 16 females, with an average age of 8.7 years. All children were asthmatic and suffered from chronic rhinosinusitis. Twenty were allergic and 15 were non-allergic. Ten healthy children were studied as normal controls. Evaluated parameters were the levels of the following cytokines: IL-1β, IL-4, IL-6, IL-8, IL-12, IFN-γ and TNF-α. Cytokines were recovered from rhinosinusal lavage and measured by immunoassays. Nasal cytology was also performed in all subjects and inflammatory cells were counted by conventional staining.Results Allergic subjects showed a significant increase of IL-4 (P 〈 0.01) and TNF-α (P 〈 0.05) and a significant decrease of IL-12 (P 〈 0.05) and of IFN-γ (P 〈 0.0001), whereas IL-1β, IL-6 and IL-8 were not significantly increased. Non-allergic children showed a significant increase of IL-4 (P 〈 0.05) and a significant decrease of IFN-γ (P 〈 0.0001), IL-12 was not significantly decreased, and IL-1β, IL-6 and IL-8 were not significantly increased. A significant inflammatory infiltrate was present in all asthmatic children. Significant correlations were demonstrated between IL-4 and IL-12 (P 〈 0.001), IL-12 and IFN-γ (P 〈 0.001), IL-8 and neutrophils (P 〈 0.01), and TNF-α and monocytes/macrophages (P 〈 0.05), in allergic asthmatics. IL-4 and IL-12 were significantly correlated (P 〈 0.05) as well as IL-8 and neutrophils (P 〈 0.01) in non-allergic asthmatics.Conclusion This study shows that allergic asthmatic children with chronic rhinosinusitis have a typical Th2 cytokine pattern, but also non-allergic asthmatic children share a similar pattern. These findings would suggest the existence of a common pathophysiological mechanism shared by upper and lower airways and are consistent with the concept of united airways disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2002.01315.x
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  • 2
    Electronic Resource
    Electronic Resource
    Nasal endoscopy in asthmatic children: assessment of rhinosinusitis and adenoiditis incidence, correlations with cytology and microbiology (2001)
    Oxford, UK : Blackwell Science Ltd
    Clinical & experimental allergy 31 (2001), S. 0 
    Details
    ISSN: 1365-2222
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Upper respiratory airway diseases may induce a worsening of asthma. Sinusitis represents one of the most common chronic diseases. The association of asthma and sinusitis varies greatly in different studies, depending on diagnostic procedures.Objective The aims were: (i) to demonstrate that nasal endoscopy may be easily feasible in asthma at paediatric age; (ii) to evaluate the incidence of rhinosinusitis and adenoiditis in children with asthma by nasal endoscopy; (iii) to correlate inflammatory parameters such as cytology and microbiological cultures with nasal endoscopy findings.Subjects and methods One hundred and forty-five asthmatic children were evaluated, 48 males and 97 females, with an average age of 7.27 years. Evaluated parameters were the incidence of rhinosinusal infections in asthmatic children, and the role of: (i) nasal endoscopy, (ii) nasal cytology, and (iii) nasal microbiology in their diagnoses.Results Nasal endoscopy was successfully performed on 128 patients. Twenty-six children had endoscopic rhinosinusitis alone, 10 had adenoiditis alone, and 35 showed endoscopic rhinosinusitis associated with adenoiditis. There were significant correlations between endoscopic rhinosinusitis and adenoiditis (P 〈 0.001), between clinical and endoscopic rhinosinusitis (P 〈 0.001), between endoscopic rhinosinusitis and adenoiditis and microbiology (P 〈 0.05 and P 〈 0.0001, respectively), and between microbiology and cytology (P 〈 0.05).Conclusion This study shows that rhinosinusal infections are common in asthmatic children. Moreover, nasal endoscopy might represent a fruitful tool in the management of asthmatic children.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1365-2222.2001.01057.x
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  • 3
    Electronic Resource
    Electronic Resource
    Vascular and Endovascular Surgery, 2nd Edition (2003)
    135 Bedford Road, PO Box 418 , Armonk , NY 10504-0418 USA . : Blackwell Science Inc
    Journal of cardiac surgery 18 (2003), S. 0 
    Details
    ISSN: 1540-8191
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1540-8191.2003.02057.x
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  • 4
    Electronic Resource
    Electronic Resource
    Optical background measurement in a potential site for the NEMO KM undersea neutrino telescope (2002)
    Springer
    The European physical journal 25 (2002), S. 67-75 
    Details
    ISSN: 1434-6052
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract. We describe the measurement of the deep sea optical background in some sites south of Capo Passero, Sicily. A continuous flux of about 440 photons cm -2 s -1 in the wavelength interval 440-550 nm is estimated due to the decays of the 40K contained in the sea water. Bioluminescence light bursts are also observed and an example of time evolution is reported. All the measurements were accomplished using a deep sea module also described in this article.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s10052-002-1015-x
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  • 5
    Electronic Resource
    Electronic Resource
    Fate of the Iliac Arteries after Repair of Abdominal Aortic Aneurysm with an Aortobifemoral Bypass Graft (1998)
    Springer
    Annals of vascular surgery 12 (1998), S. 330-334 
    Details
    ISSN: 1615-5947
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100169900163
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  • 6
    Electronic Resource
    Electronic Resource
    The effect of femoral arteriography on the incidence of groin contamination and postoperative infections (1990)
    Springer
    Annals of vascular surgery 4 (1990), S. 328-332 
    Details
    ISSN: 1615-5947
    Keywords: Arteriography ; femoral ; infection ; groin wound contamination ; aortoiliac disease
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A prospective study is presented on the effects of preoperative femoral arteriography on bacterial contamination and postoperative wound complications from groin incisions. Forty-four femoral reconstructive procedures (88 groin incisions) for aortoiliac disease were performed. Positive cultures occurred in 43.2% of patients and in 30.7% of the 88 incisions. There was no correlation found between the site of arteriography and positive cultures (Spearman correlation coefficient, p 〉 .10). No correlation was found between the presence of hematoma due to arteriography and subsequent positive groin culture (Spearman correlation coefficient, p 〉 .10). A higher incidence of positive cultures did occur for patients who had a difficult arteriographic procedure (Fisher's exact test, p=.020) or whose reconstructive procedure was greater than four hours (Fischer's exact test, p=.047). Seven patients had postoperative groin wound complications (15.9%), including three lymph leaks (6.8%) and four confirmed or suspected infections (9%). There were no graft infections. No correlation was found between the site of arteriography and the site of wound complication (Spearman correlation coefficient, p 〉 .10). Neither positive culture results nor difficult arteriography nor presence of hematoma were accurate predictors of postoperative wound complications. We conclude that transfemoral arteriography does not increase the risk of complications of arterial reconstruction involving a femoral anastomosis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02000494
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  • 7
    Electronic Resource
    Electronic Resource
    Intravenous digital subtraction arteriography in the evaluation of vascular grafts (1991)
    Springer
    Annals of vascular surgery 5 (1991), S. 223-228 
    Details
    ISSN: 1615-5947
    Keywords: Digital subtraction arteriography ; intravenous digital subtraction arteriography See digital subtraction arteriography ; graft evaluation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Between 1982 and 1986 intravenous digital subtraction arteriography was used to evaluate vascular grafts in 97 patients (54 males, 43 females). Indications included recurrent symptoms, absent or diminished pulses, a drop in Doppler pressure measurements, and clinical uncertainty with respect to graft patency. Problems identified included graft stenosis, stenosis of the anastomosis or its distal vessels, false aneurysm, arteriovenous fistula and emboli. Forty-eight operations were carried out following intravenous digital subtraction arteriography, and radiographic findings were verified surgically. Twice, intravenous digital subtraction arteriography did not show significant graft findings which were discovered at surgery. Thus intravenous digital subtraction arteriography showed a sensitivity of 95.8% and specificity of 100%. Complications following intravenous digital subtraction arteriography were: two patients developed urticaria, and one superficial thrombophlebitis. There were no cases of pulmonary edema or death. In conclusion intravenous digital subtraction arteriography is very useful in the diagnosis of graft-related problems if done on a selective basis looking at graft and anastomosis site only, intravenous digital subtraction arteriography is done on an outpatient basis, has high sensitivity and specificity, good patient acceptance, is safe, fast and is less expensive than conventional arteriography.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02329377
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  • 8
    Electronic Resource
    Electronic Resource
    Ischemic damage to the spinal cord following end-to-side aortobifemoral bypass (1993)
    Springer
    Annals of vascular surgery 7 (1993), S. 569-576 
    Details
    ISSN: 1615-5947
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A patient presenting with urinary retention was found to have progressive spinal cord ischemia subsequent to an end-to-side aortobifemoral bypass for atherosclerotic disease. This serves as a vivid reminder of the possibility of this complication even in ischemic disease and that urinary retention may be the initial symptom of cord ischemia. A review of the literature on spinal cord ischemia following abdominal aortic surgery is presented.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02000153
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