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  • 1
    Electronic Resource
    Electronic Resource
    MAST CELLS OF THE OMENTUM IN RELATION TO STATES OF ADRENOCORTICAL DEFICIENCY AND EXCESS (1953)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 56 (1953), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1953.tb27390.x
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  • 2
    Electronic Resource
    Electronic Resource
    ADRENAL STEROIDS AND THE SECRETION OF DIGESTIVE ENZYMES (1955)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 61 (1955), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1955.tb42482.x
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  • 3
    Electronic Resource
    Electronic Resource
    THE RELATIONSHIP OF THE ADRENAL, THYROID, AND PITUITARY GLANDS TO THE GROWTH OF HAIR (1951)
    Oxford, UK : Blackwell Publishing Ltd
    Annals of the New York Academy of Sciences 53 (1951), S. 0 
    Details
    ISSN: 1749-6632
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1749-6632.1951.tb31970.x
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  • 4
    Electronic Resource
    Electronic Resource
    Distribution of growth hormone-release-inhibiting hormone (somatostatin) in the rat brain as observed with immunocytochemistrySupported in part by a Program Project Grant (HD-08333) directed by Dr. A. R. Midgley, Jr., from the National Institute for Child Health and Human Development. (1976)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 186 (1976), S. 343-355 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The objective was to determine the distribution of growth hormone-release-inhibiting hormone (somatostatin) in the rat brain using the peroxidase-antiperoxidase immunocytochemical method with antisera prepared against unconjugated, synthetic somatostatin. Somatostatin occurred in low quantity in the organum vasculosum of the lamina terminalis. It was present throughout the full length of the median eminence and occupied the entire width between the tuberoinfundibular sulci. Most somatostatin was located in the dorsal portion of the external lamina, and the amount varied according to the mediolateral position. The bodies labeled for somatostatin were most often granules; occasionally they appeared as clusters of granules that seemed to be membrane-enclosed. Some of these bodies appeared to be portions of axons. Many of the larger bodies were arranged alongside tanycytes, but no label was distributed generally in tanycyte cytoplasm. Somatostatin was highly concentrated in the proximal one-quarter of the infundibular stem and appeared in lower concentration throughout the distal portion of the stem. It was absent from the pars nervosa and pars intermedia of the pituitary gland. The distribution of somatostatin in the median eminence differed considerably from that of gonadotropinreleasing hormone.Somatostatin was identified in the ventromedial and/or dorsomedial hypothalamic nuclei of only two animals. Here it was probably located in axons that terminated on neuronal cell bodies but also may have been present in a restricted portion of the perikaryonal cytoplasm.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091860302
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  • 5
    Electronic Resource
    Electronic Resource
    Identification of the corticotropin cell in rat hypophyses with peroxidase-labeled antibodySupported in part by USPHS research grants HD 03159-01Al and HD 02193, and a grant from the University of Michigan Horace H. Rackham School of Graduate Studies. (1970)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 166 (1970), S. 557-567 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: Utilization of peroxidase-labeled antibody to porcine corticotropin permitted the delineation of a distinctive cell in the hypophyseal pars distalis of the rat that appears to be the source of corticotropin. Corticotropin cells were stellate and possessed processes that ended on the walls of sinusoids. Corticotropin cells composed a small percentage of the total cell population, and were distributed throughout the gland except that they were less common posteriorly, superiorly, and immediately alongside the pars intermedia. Alteration in size of corticotropin cells was related directly to change in corticotropin content of the gland as effected by differing physiological conditions. Thus, they were larger in the female than in the male and were enlarged after adrenalectomy of the male; they became much smaller following treatment of the female with cortisol. Some corticotropin cells stained with aldehyde fuchsin and the periodic acid-Schiff (PAS) reaction. These reactions were more intense if hormone antibody and the gamma-globulin conjugate had been applied previously. However, the capacity of some corticotropin cells to stain weakly with PAS without prior application of antibody suggests that they may contain mucoprotein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091660402
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  • 6
    Electronic Resource
    Electronic Resource
    Differentiation of growth hormone- and prolactin-containing acidophils with peroxidase-labeled antibodySupported in part by USPHS research grants HD 03159-01A1 and HD 02193, and a grant from the University of Michigan Horace H. Rackham School of Graduate Studies. (1969)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 164 (1969), S. 163-171 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: In order to verify the concept that growth hormone and prolactin are contained in two different populations of acidophils, sections of Bouin-fixed rat hypophyses were stained immunochemically. For this purpose the histochemical demonstration of peroxidase was utilized after sequential application to the tissue section of rabbit antiserum to human growth hormone (or antiserum to rat prolactin) followed by application of peroxidase-labeled sheep antiserum to rabbit gamma-globulin. It was found that growth hormone cells and prolactin cells, when revealed immunochemically, corresponded structurally to cell types that could be differentiated with reasonable certainty in sections stained with the Masson trichrome procedure. When delineated immunochemically, growth hormone cells were larger and more densely arranged in the adult male than in the intact female; they exhibited little change in the female after ovariectomy. In contrast, prolactin cells were large and frequent in the female hypophysis but were small and less frequent in the male and in the female after ovariectomy. By double-staining, growth hormone and prolactin cells were differentiated in the same section. It was concluded that (a) growth hormone and prolactin are contained in, and presumably secreted by, two different populations of acidophils; and (b) the Masson procedure permits a reasonably accurate differentiation of the two cell types.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091640204
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  • 7
    Electronic Resource
    Electronic Resource
    The ultrastructure of megakaryocytes and blood platelets in the rat spleenSupported in part by research grants from the National Institutes of Health A-131 (C9) and from the Upjohn Company. (1964)
    New York, NY [u.a.] : Wiley-Blackwell
    The @Anatomical Record 149 (1964), S. 251-267 
    Details
    ISSN: 0003-276X
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The cytoplasm of the megakaryocyte in the rat spleen possesses three zones, the perinuclear, intermediate and marginal. The perinuclear zone is characterized by the presence of Golgi apparatus, ribosomes, endoplasmic reticulum, and mitochondria. These organelles are found also in the more voluminous intermediate zone which in addition exhibits platelet granules and an extensive development of vesicles from smooth-surfaced endoplasmic reticulum to form demarcation membranes by coalescence. The marginal zone is almost devoid of the organelles and inclusions present elsewhere. Shedding of platelets appears to occur by extension of a paired demarcation membrane from the intermediate zone to the cell membrane and subsequent separation of its lamellae so that all of the essential organelles and inclusions of the intermediate zone may be included within the platelet. In addition, platelets contain vesicles which are probably pinocytotic in nature. Platelets are sometimes engulfed by the cytoplasm of phagocytic cells.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/ar.1091490208
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  • 8
    Electronic Resource
    Electronic Resource
    Cellular composition of the human pituitary pars tuberalis as revealed by immunocytochemistry (1977)
    Springer
    Cell & tissue research 182 (1977), S. 151-163 
    Details
    ISSN: 1432-0878
    Keywords: Pituitary gland (Human) ; Pars tuberalis ; Cytology ; Gonado tropic cell
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary An attempt was made to determine if any of the specialized secretory cell types common to the pars distalis also occur in the pars tuberalis of the human hypophysis. Available for study were 18 specimens of the inferior pars tuberalis, which partially surrounds the infundibular stem, and 3 specimens of the superior pars tuberalis that is attached to the median eminence. Antisera to human somatotropin, mammotropin, chorionic gonadotropin, follicle-stimulating hormone, FSH β, luteinizing hormone, LH β, thyrotropin, TSH β, as well as to β 1–24-corticotropin, porcine β 17–39-corticotropin, and ovine LH were used with the Sternberger peroxidase-antiperoxidase immunocytochemical procedure to identify the probable cells of origin for these hormones. The evidence indicated that gonadotropic cells constitute the major portion of the parenchymal cell population in the pars tuberalis. They occurred throughout all of the pars tuberalis and were usually arranged in clusters. Somatotropic, mammotropic, corticotropic, and thyrotropic cells were rare and not found in all specimens. When present, they often formed a common group suggesting that their occurrence in the pars tuberalis resulted from displacement of primordial tissue of the pars distalis during embryogenesis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00220585
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  • 9
    Electronic Resource
    Electronic Resource
    Immunocytochemical analysis of cells in the pars tuberalis of the rat hypophysis with antisera to hormones of the pars distalis (1975)
    Springer
    Cell & tissue research 156 (1975), S. 443-449 
    Details
    ISSN: 1432-0878
    Keywords: Pituitary gland ; Cytology ; Pars tuberalis ; Immunocytochemistry ; Luteinizing hormone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Summary The objective was to acquire evidence regarding the secretory capacity of cells in the pars tuberalis of the rat pituitary by the application of immunocytochemical staining. For this purpose the conjugated antibody and immunoglobulin-enzyme bridge techniques were utilized with antisera to the following hormones of the pars distalis: human somatotropin, human thyrotropin, human β-melanotropin, ovine luteinizing hormone (LH), porcine β17–39-corticotropin, and β1–24-corticotropin. Only LH-containing cells were demonstrated. They were exceedingly rare in the cephalic pars tuberalis beneath the median eminence. The frequency of LH-cells was greater in the pars tuberalis associated with the infundibulum and increased distally. LH-cells were most common ventrolateral to the infundibular stem and occurred singly and in clusters. These results indicate that following hypophysectomy the portion of the pars tuberalis that remains in situ has the capacity to secrete only LH of all the pars distalis hormones.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00225104
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  • 10
    Electronic Resource
    Electronic Resource
    The cytological structure of the human chorionic villus and decidua parietalis (1944)
    New York, NY [u.a.] : Wiley-Blackwell
    American Journal of Anatomy 74 (1944), S. 291-325 
    Details
    ISSN: 0002-9106
    Keywords: Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Additional Material: 1 Tab.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1000740302
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