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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 19 (2005), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  The 1- and the 2-euro coins consist of nickel alloys, which release nickel. The nickel released by far exceeds the amount allowed by the European Union Nickel Directive referring to products intended to come into direct and prolonged contact with the skin. As there is only temporary contact with the skin, the clinical relevance of nickel-containing coins with regard to nickel dermatitis is a matter of debate, although there is evidence that the nickel released from the coins affects some nickel-sensitive subjects through occupational exposure.Objectives  Our aim was to study skin reactivity to euro coins, and to correlate the frequency and intensity of coin patch test responses to sensitization thresholds to nickel.Patients and methods  Sixty-four nickel-sensitized and 30 non-nickel-sensitized subjects were patch tested with serial dilutions of nickel sulfate (5, 1, 0.5, 0.1, 0.05, 0.01 and 0.005% in distilled water) and with coins. Italian coins (500, 200, 100 and 50 lira) and euro coins (2 and 1 euros, 20 and 5 euro cents) were used for patch testing and compared.Results  The application of 1- and 2-euro coins to the skin induced eczematous reactions, being more frequent and intense in comparison with those provoked by other coins. A correlation between intensity of responses to coin patch tests and sensitization threshold to nickel was observed. Patients with the strongest reactions to 1- and 2-euro coins showed positive responses to the lowest nickel concentrations.Conclusions  The nickel content in euro coins represents a possible health hazard, especially for highly nickel-sensitive subjects. We recommend that nickel sulfate patch tests should be performed at different concentrations to determine sensitization thresholds at least in individuals with occupational exposure to coins.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford, UK; Malden, USA : Blackwell Publishing Ltd/Inc.
    Contact dermatitis 50 (2004), S. 0 
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We describe a case of a 42-year-old non atopic man with a history of ano-perianal eczema in consequence of the use of anti-haemorroidal ointments and allergic contact dermatitis to Myroxylon pereirae, benzocaine, paraben mix and paraphenylenediamine. He was referred to our Unit for a strong eczematous reaction in the genital area with a marked oedema of the balanoprepuzial region that had appeared some hours after the use of a condom (Settebello-Hatù® Durex) made of natural latex and containing a retarding cream composed with benzocaine 5%, polyethylene glycol plus glycerin 94,7% and paraben 0,3% as preservative. The suspension of the use of the condom and treatment with a corticosteroid cream healed the eruption in few days. Patch testing with the SIDAPA (Società Italiana di Dermatologia Allergologica, Professionale e Ambientale) standard series, an additional rubber series, a piece of the rubber’s condom washed clean of cream and the condom’s cream gave positive reactions to Myroxylon pereirae, benzocaine, paraben mix, paraphenylenediamine and condom’s cream. Further patch test with the other ingredients of condom’s cream was negative as well as latex prick test. We discuss about the ethiologic agents and the most useful diagnostic test in allergic contact dermatitis condom-related and the preventive measures that should be adopted.
    Type of Medium: Electronic Resource
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