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  • 1
    Electronic Resource
    Electronic Resource
    Genetic variability in the cosmopolitan deep-water ophiuran Ophiomusium lymani (1974)
    Springer
    Marine biology 27 (1974), S. 51-57 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A population of the cosmopolitan deep-sea ophiuran Ophiomusium lymani was studied by gel electrophoresis, and proved to be highly variable genetically; about 53% of the 15 loci studied are polymorphic, and the average individual is heterozygous at about 17% of the loci. This is approximately the same genetic variability displayed by other species, belonging to other phyla or classes, from the same deep-sea trawl. A similarly high level of genetic variation occurs in deep-sea organisms in general, and in a shallow-water tropical species. Both the deep-sea and the tropics are trophically stable environments. On the other hand, low genetic variabilities have been found in marine species from trophically unstable environments. These data suggest that any phylogenetic effects on genetic variability are secondary, and that the trophic regime may be of major importance in determining genetic strategies of adaptation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00394760
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  • 2
    Electronic Resource
    Electronic Resource
    High genetic variability in a population of Tridacna maxima from the Great Barrier Reef (1975)
    Springer
    Marine biology 33 (1975), S. 341-345 
    Details
    ISSN: 1432-1793
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract A population of the bivalve mollusk Tridacna maxima (Röding) from Hron Island, Great Barrier Reef, Australia, was studied by gel electrophoresis, and proved to be highly variable genetically, with an average heterozygosity of about 22%. This compares closely with a population of T. maxima from Enewetak (Eniwetok) Atoll, with an average heterozygosity of about 20%, very high for marine organisms. Enewetak Atoll was the site of a series of nuclear tests. The Heron Island study verifies that the high variability is natural, and supports the hypothesis that species from trophically stable environments tend to be highly variable genetically.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00390572
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Italian multicenter study on Epiquick®, Rapid Patch Test® and TRUE TestTM (1994)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the European Academy of Dermatology and Venereology 3 (1994), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Using 3 different ready-to-apply patch test systems (Epiquick®= EPI; Rapid Patch Test®= RPT; TRUE TestTM= TT), 316 patients sensitive to at least one allergen were studied in order to investigate the reproducibility of these tests in comparison with the Finn Chamber ®(FC) technique. Each patient was tested with a different ready-to-use system. Each test was compared to the same allergen applied with FC to either side of the upper back. Comparisons were made using EPI, RPT, and TT in 93 (183 tests), 119 (262 tests), and 104 (242 tests) patients respectively. When a positive test result occurred on only one side of the back, the concordance was defined as negative. Similarly, doubtful reactions on either side corresponding to positive or negative results were considered as non concordant. The concordance of positive reactions was 80.9% between the EPI and the FC technique, 77.5% between the RPT and the FC technique, and 72.3% between the TT and the FC technique. The frequency of questionable (+?) and irritant reactions (IR) was about the same for the different tests. Nevertheless, when comparing the positive reactions vs +?, IR, or negative reactions in paired tests, positive results were more frequently obtained with the FC technique. Our data suggest that the standard method with FC allows a better detection of contact allergy than the new ready-to-use systems tested in this study.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.1994.tb00410.x
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  • 4
    Electronic Resource
    Electronic Resource
    Reactivity to euro coins and sensitization thresholds in nickel-sensitive subjects (2005)
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 19 (2005), S. 0 
    Details
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  The 1- and the 2-euro coins consist of nickel alloys, which release nickel. The nickel released by far exceeds the amount allowed by the European Union Nickel Directive referring to products intended to come into direct and prolonged contact with the skin. As there is only temporary contact with the skin, the clinical relevance of nickel-containing coins with regard to nickel dermatitis is a matter of debate, although there is evidence that the nickel released from the coins affects some nickel-sensitive subjects through occupational exposure.Objectives  Our aim was to study skin reactivity to euro coins, and to correlate the frequency and intensity of coin patch test responses to sensitization thresholds to nickel.Patients and methods  Sixty-four nickel-sensitized and 30 non-nickel-sensitized subjects were patch tested with serial dilutions of nickel sulfate (5, 1, 0.5, 0.1, 0.05, 0.01 and 0.005% in distilled water) and with coins. Italian coins (500, 200, 100 and 50 lira) and euro coins (2 and 1 euros, 20 and 5 euro cents) were used for patch testing and compared.Results  The application of 1- and 2-euro coins to the skin induced eczematous reactions, being more frequent and intense in comparison with those provoked by other coins. A correlation between intensity of responses to coin patch tests and sensitization threshold to nickel was observed. Patients with the strongest reactions to 1- and 2-euro coins showed positive responses to the lowest nickel concentrations.Conclusions  The nickel content in euro coins represents a possible health hazard, especially for highly nickel-sensitive subjects. We recommend that nickel sulfate patch tests should be performed at different concentrations to determine sensitization thresholds at least in individuals with occupational exposure to coins.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1468-3083.2005.01219.x
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  • 5
    Electronic Resource
    Electronic Resource
    Influence of Packaging Films on the Sensory and Microbiological Evolution of Minimally Processed Borage (Borrago officinalis) (2003)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 68 (2003), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: The atmospheres prevalent in borage packaged in 5 different films, together with different water-vapor permeabilities of the films, determined the evolution of the visual and microbiological quality of borage. PVC films proved inadequate to extend the sensory quality since the samples packaged with the films were spoiled on day 9, whereas among the P-Plus films, the least permeable film was the most adequate to extend the sensory quality of borage until day 15. For most of the treatments, no correlation between the microbial growth and changes in appearance was found. Thus, some treatments with a fair sensory evaluation had microbial counts higher than those allowed by the European legislation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.2003.tb08286.x
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  • 6
    Electronic Resource
    Electronic Resource
    Allergic contact dermatitis from retinoic acid (1995)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 32 (1995), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1995.tb00846.x
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  • 7
    Electronic Resource
    Electronic Resource
    Contact dermatitis from pyrrolinitrin (1983)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 9 (1983), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1983.tb04377.x
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  • 8
    Electronic Resource
    Electronic Resource
    Allergic contact dermatitis from Cerumenex® in a child (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 21 (1989), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1989.tb04763.x
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  • 9
    Electronic Resource
    Electronic Resource
    Influence of topical cyclosporin A on patch test reactions (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 20 (1989), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1989.tb03132.x
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  • 10
    Electronic Resource
    Electronic Resource
    Adverse skin reactions to vitamin K1: report of 2 cases (1998)
    Oxford, UK : Blackwell Publishing Ltd
    Contact dermatitis 38 (1998), S. 0 
    Details
    ISSN: 1600-0536
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Vitamin K is essential to the biosynthesis of prothrombin and other clotting factors (VII, IX and X), and is mostly used for the prophylaxis of bleeding disorders, mainly in patients with hepatic disfunction (1). 4 different pharmacological forms exist: the natural form K1 (phytomenadione); K2 (menaquinone), which is derived from intestinal bacterial action; K3 (menadione); and K4 (menadiol). The latter 2 are synthetic products. In Italy, only vitamin K1 is marketed (2).Adverse cutaneous reactions to vitamin K are rare; 2 are mainly reported: an erythematous plaque (3, 4) or pseudo-scleroderma (5) at the injection site. Contact dermatitis and localized urticarial lesions have also been described (2).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0536.1998.tb05774.x
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