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  • 1
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 27 (1955), S. 1575-1580 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    Analytical chemistry 27 (1955), S. 1374-1378 
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1432-055X
    Keywords: Schlüsselwörter Offenes Foramen ovale ; Transösophageale Echokardiographie ; PEEP ; Key words Patent foramen ovale ; Transoesophageal echocardiography ; PEEP
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Abstract Intraoperative paradoxical air embolism may occur even if a patent foramen ovale (PFO) is excluded by contrast transoesophagal echocardiography (TEE) under 20 cmH2O positive airway pressure. It is questionable whether the combination of PEEP and ventilation with a large tidal volume increases the sensivity of contrast TEE in detecting a PFO. Methods. Eighty healthy patients (ASA status I, II) scheduled for surgery in the supine position and ranging from 25 to 72 years of age were investigated by TEE, which was performed in the biatrial viewing mode (short axis). Echocardiographic contrast (10 ml agitated gelatine solution) was injected during two different ventilation manoeuvres. Manoeuvre I: Contrast injection during the application of 20 cmH2O positive airway pressure for 5 s. The pressure was released when the right atrium became completely opacified by echo targets. The injected bolus was observed throughout the ventilatory cycle, with special attention being given to early expiration and systole. A right-to-left shunt was assumed if five echo targets were observed in the left atrium. Manoeuvre II: Contrast injection during ventilation with PEEP (15 cmH2O), a tidal volume of 1,200 ml, and a respiratory rate of 6/min. Results. The frequency of a PFO causing a right-to-left interatrial shunt was 8.7% (7 cases) in manoeuvre I and 15% (12 cases) in manoeuvre II. In one case a PFO was diagnosed intraoperatively by chance. Discussion. The use of provocation manoeuvres including ventilation with PEEP and high tidal volumes might improve the ability to detect a PFO presenting with right-to-left interatrial shunt by intraoperative contrast TEE, but does not have 100% sensitivity. However, our results clearly indicate that ventilation with PEEP and high tidal volumes may predispose to paradoxical embolism.
    Notes: Zusammenfassung Paradoxe Luftembolien sind trotz präoperativem Ausschluß eines offenen Foramen ovale (PFO) mittels transösophagealer Echokardiographie (TEE) unter Durchführung eines Ventilationsmanövers mit einem endinspiratorischen Atemdruck von 20 cm H 2 O berichtet worden. Es stellt sich die Frage, ob die Empfindlichkeit der Kontrast-TEE unter Ventilationsmanövern mit PEEP-Beatmung und hohem Atemhubvolumen erhöht werden kann. Untersucht wurden 80 Patienten der ASARisikogruppen I und II, im Alter von 25 bis 72 Jahren. Der biatriale Blick in der kurzen Achse wurde als Standardeinstellung der TEE verwendet. Die Gabe des Kontrastmittels erfolgte unter zwei verschiedenen Ventilationsmanövern. Manöver I: Injektion des Kontrastmittels bei einem endinspiratorischen Druck von 20 cmH 2 O für die Dauer von 5 s. Manöver II: Injektion des Kontrastmittels unter Beatmung mit PEEP von 15 cmH 2 O, bei einem Atemhubvolumen von 1200 ml und einer Atemfrequenz von 6/min. Die Häufigkeit eines PFO mit Rechts-links-Shunt unter dem Manöver I betrug 8,7% (7 Patienten), unter dem Manöver II 15% (12 Patienten). Bei einem weiteren Patienten gelang der Nachweis eines PFO erst intraoperativ (Zufallsbefund). Die Anwendung von Provokationsmanövern mit PEEP-Beatmung und einem hohem Atemhubvolumen bei der intraoperativen Kontrast-TEE kann möglicherweise zu einer Erhöhung der Nachweisquote eines PFO mit Rechts-links-Shunt beitragen. Eine 100%ige Sensitivität wird hiermit jedoch nicht erreicht, falsch negative Befunde lassen sich nicht ausschließen.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 26 (1970), S. 615-615 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Wirkung des arteriellen O2-Partialdruckes auf die Durchblutung des Grosshirns, Kleinhirns und Hirnstammes bei normalen und erhöhten CO2-Partialdrucken im arteriellen Blut wird an der anaesthesierten Katze untersucht. Die Wirkung des PaO2 ist von der Höhe des PaCO2 abhängig.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1432-1106
    Keywords: Regional cerebral blood flow ; Isotope clearance studies ; Solid state detectors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Regional cerebral blood flow was measured by means of isotope clearance with a new type of solid state beta-sensitive needle detector (diameter 0.9 mm) introduced into the brain tissue in acute cat experiments. The flow values obtained within the cortex were compared with values recorded above the same cortical region with the same needle detector, or with a small GM-tube. The insertion of the needle detector into the brain tissue gave rise to injury (checked histologically) which deformed the clearance curves in a manner suggesting that the normal circulation had been destroyed within the tissue from which the measurements were made.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 112 (1991), S. 65-70 
    ISSN: 0942-0940
    Keywords: Chemonucleolysis ; lumbar disc surgery ; disc herniation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A group of 100 patients submitted to microsurgical treatment for herniated lumbar disc following unsuccessful chemonucleolysis with chymopapain were retrospectively compared to a statistically comparable group of patients primarily submitted to microsurgery. This comparison demonstrated that previous unsuccessful chemonucleolysis has no influence on either the short-term or the long-term results of subsequent microsurgery.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 0942-0940
    Keywords: Anosmia ; sitting position ; postoperative complication
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Although the sitting position offers advantages for posterior fossa surgery, it is accompanied by complications such as air embolism and pneumatocephalus. Subdural and epidural haematomas are less common postoperative complications of posterior fossa surgery. To the best of our knowledge, however, anosmia is not a known sequela of surgery in the sitting position. It has been described following aneurysm surgery in the rostral part of the circle of Willis and is, of course, well known in traumatic brain injury.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 0942-0940
    Keywords: Keywords: Carotid stenosis; carotid thrombo-endarteriectomy; intra-operative Doppler ultrasonography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary  Large multicenter studies have recently provided long-term results substantiating the superiority of surgical as compared to conservative treatment for symptomatic and asymptomatic extracranial internal carotid stenoses of more than 70%. These results led to an increase in the frequency of thrombo-endarteriectomies. However, indications are limited by the peri-operative complication rate. This explains the need for intra-operative quality control.  The present study compares the standard method of intra-operative quality control in carotid surgery, i.e., intra-operative angiography (IOA), with direct intra-operative Doppler ultrasonography (IDU). Thirty-four patients who underwent carotid thrombo-endarteriectomy (carotid TEA) for a symptomatic (n=15) or asymptomatic (n=19) carotid stenosis of more than 70% were submitted to both intra-operative IOA and IDU. The sensitivity and specificity of the two techniques were compared in the light of the intra-operative findings.  IDU seems to be superior to IOA in the detection of vasospasm. IOA has a higher sensitivity in demonstrating minisaccules, which, however, are not therapeutically relevant. The other findings obtained with both methods were considered to be of equal value. There were no false negative results by IDU regarding therapeutically relevant findings.  We therefore consider it advisable to apply IDU in every case of carotid TEA. IOA should be performed in patients with vessel changes detected by IDU.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Acta neurochirurgica 142 (2000), S. 1397-1397 
    ISSN: 0942-0940
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 0942-0940
    Keywords: fractional electro-coagulation ; gasserian ganglion ; trigeminal neuralgia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In his experience with 531 surgical procedures for the relief of trigeminal neuralgia between 1955 to 1970, the author developed a strong preference for the percutaneous electro-coagulation of the gasserian ganglion. Although the method was repeatedly modified in the early years, a standardized technique of controlled, selective and fractional coagulation in the semiawake state of neurolept-anaesthesia was used since 1963 in 183 of his 311 patients, treated in this manner. The advantages of the method, particularly in comparison to open intracranial root sections, are: Minimal operative risk, control of operative effect during the operation, small sensibility deficit, low rate of complications, short hospitalization, short convalescence and satisfactory final result in 93% of the patients (after a second or third coagulation, if needed) in a three-year follow-up period.
    Type of Medium: Electronic Resource
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