ISSN:
1573-8221
Keywords:
central nervous system
;
strain (neurosis)
;
castration
;
mercazolyl
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract Functional strain on the CNS was combined in chronic experiments on seven dogs with other factors changing the hormonal status of the animal-castration and injection of mercazolyl in doses of 1.5–2.5 mg/kg (group 1). The six control dogs (group 2) underwent castration and injection of mercazolyl only. The animals of group 1 developed persistent hypercholesteremia, atherosclerotic changes in various intramural arteries, especially of the myocardium, and also degenerative changes in the parenchyma of certain organs, which were not found in the animals of group 2. The results of this investigation demonstrate the important role of functional strain on the CNS as a leading “risk” factor responsible for disturbances of the regulation of lipid metabolism and the development of atherosclerotic changes in the vessels.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00800484
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