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  • 1
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Journal of the European Academy of Dermatology and Venereology 16 (2002), S. 0 
    ISSN: 1468-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background  Owing to the increase of an immigrant population and of Italian citizens travelling for tourism or on business, it is nowadays possible to observe clinical pictures characteristic of tropical regions, often with indistinct symptoms. One of these is Loa loa infestation, or loiasis, a form of filariasis caused by Loa loa and transmitted by the Chrysops fly. We present the case of a male immigrant from Cameroon. Characteristic symptoms were intense xerosis, mostly of the third inferior part of the legs, intensely pruritic, with numerous lesions from scratching. No benefit was obtained by emollient topics, anti-acarus and systemic antihistamines.Method  Serum samples and Giemsa, haematoxylin, haematoxylin + Giemsa concentration-on-membrane stains, have evidenced the presence of Loa loa microfilariae.Results  A diagnosis for L. loa (loiasis) infestation was made.Conclusions  At the beginning of the migration phenomenon, particularly from Africa, Italian physicians, especially dermatologists, were eagerly looking for ‘tropical’ diseases; this approach can be defined as ‘Salgari's syndrome’ from the name of the Italian novelist who, though never travelling out of Italy, had perfectly described environments and habits typical of far away countries. Now, conversely, we have to avoid the opposite approach of considering real tropical diseases as related to social or psychological difficult conditions.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 161-166 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have explored the mechanisms underlying the gettering of Pt atoms dissolved in crystalline Si. By using Pt implantation at different fluences followed by a thermal process at 970 °C for 5 h we were able to prepare crystalline silicon wafers containing a uniform Pt concentration in the range 2×1012–2×1014 atoms/cm3. Subsequently, a heavily doped n-type region was produced on one side of the wafer by P diffusion at 900 °C. Following this deposition process we have studied the kinetics of Pt gettering to the P-doped region in the temperature range 700–970 °C and for annealing times ranging from 30 min to 48 h. Lifetime measurements by means of a contactless technique were used to detect the depletion of Pt in the bulk of the wafer due to the gettering process. The large range of initial Pt concentrations that we have explored allowed us to identify and separate the kinetics and thermodynamics constraints that determine the gettering efficiency and to propose a phenomenological model for the gettering of Pt. In particular, it has been found that the kinetics of the gettering process are driven by the dissolution of immobile substitutional Pt atoms into interstitial sites. This process is assisted by Si self-interstitials and characterized by an activation energy of 0.4 eV. Moreover, the equilibrium distribution of Pt is thermodynamically determined by a segregation coefficient of the Pt atoms between the gettering sites and the silicon matrix. This segregation coefficient, and hence the gettering efficiency, decrease when the temperature of the gettering process is increased and is described by an activation energy of 2.5 eV. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 80 (1996), S. 4322-4327 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: We have investigated the efficiency and the thermal stability of Pt gettering at different sites in crystalline Si. In particular, we compared the gettering performances of heavily n-type doped regions formed by P diffusion, cavities formed after high-temperature annealings of He implanted Si, and damage induced by ion implantation of B, C, or Si. These sites were introduced on one side of wafers containing a uniform Pt concentration in the range 1×1013–5×1014 atoms/cm3. The uniform concentration of Pt was attained by means of Pt implantation followed by a high-temperature thermal process. The gettering efficiency of the different sites was monitored during thermal processes at 700 °C for times ranging from 1 to 48 h. Thermal stability of gettering was investigated with a subsequent thermal process in the temperature range 750–900 °C during which part of the gettered Pt is released in the bulk of the wafer. The kinetics of Pt gettering at the different sites is found to be similar since it is fully dominated by the kick-out diffusion mechanism of the metal impurity. The thermal stability is instead site-dependent and can be described in terms of an effective binding enthalpy of 1.9, 2.6, and 3.0 eV between Pt atoms and cavities, P-doped region, and ion-implantation damage, respectively. The physical meaning of the binding enthalpy is investigated and discussed. © 1996 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    s.l. : American Chemical Society
    The @journal of organic chemistry 33 (1968), S. 3344-3346 
    ISSN: 1520-6904
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 63 (1993), S. 1194-1196 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The transport of material from target to substrate has been monitored in the pulsed laser deposition of Pb(Ti0.48Zr0.52)O3 films on p-doped Si(100) using two in situ diagnostics, namely plume fluorescence spectroscopy and plume ion mass spectrometry. The as-grown PZT films are specular, with thicknesses which decrease from 350 to 250 nm on a radius 5 mm from the center and show a dielectric hysteresis with typical remanent polarizations and coercive fields of 0.2 μC/cm2 and 124 kV/cm, respectively. The analysis of the plume fluorescence emission and ionic yield indicates that oxidation of the ablated material occurs during transport from target to substrate and that, in order to grow ferroelectric thin films, the substrate should be located in the region of the plume where the relative concentrations of metal oxides and clusters increase.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Science Ltd
    Clinical and experimental dermatology 30 (2005), S. 0 
    ISSN: 1365-2230
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 58 (1986), S. 157-164 
    ISSN: 1432-1246
    Keywords: Serum bile acid ; Exposure to organic solvents ; Hepatotoxicity ; Liver function ; Biological monitoring
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Liver injury has long been associated with occupational exposure to a wide variety of chemicals. The controversial data existing in relation to hepatotoxicity of organic solvents might be explained as a consequence of the different exposures or it may well be that the tests used for evaluating liver function might not be sensitive enough to detect any mild changes at an early stage. To study liver function during exposure to solvent mixtures, we determined serum bile acid (SBA) concentrations as compared with conventional liver function tests in a selected group of workers (n = 30) occupationally exposed to a mixture of organic solvents (mostly toluene, xylene, acetone, n-butylacetate, n-butanol, ethylacetate) and in a reference group (n = 20). The mean levels of liver enzyme activities and bilirubin concentrations in the two groups were similar, whereas mean SBA levels increased in the exposed group (8.0 ± 6.0 μmol/l vs 2.8 ± 1.4 μmol/l) and the difference as compared with the controls was significant (P 〈 0.01). In 73% of the exposed workers, SBA levels were higher than 5.6 μmol/l (the cut-off value) as compared with 5% of the controls. These results demonstrate the higher sensitivity in detecting liver dysfunction achieved with the SBA test as compared with conventional hepatic function tests. As increased SBA concentrations are considered to reflect an impairment of anion transport across the liver, higher SBA levels in the group of workers exposed to organic solvents might be explained as a slight and early sign of liver dysfunction. Therefore, SBA determination in biological monitoring of workers exposed to potentially hepatotoxic chemicals might be proposed.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 67 (1995), S. 353-358 
    ISSN: 1432-1246
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 72 (1999), S. 338-342 
    ISSN: 1432-1246
    Keywords: Key words European Union ; Occupational physicians ; Educational curriculum ; Training
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The framework directive on improvements in the safety and health of workers is being implemented into the national legislation of European Union countries, and occupational physicians are requested to play a key role in undertaking preventive measures. Since there is no common specific requirement for the training and education of these health professionals, this report aims to provide a comparative picture of the educational process across European Union training bodies. Each curriculum provides theoretical knowledge and practical experience, but deep differences exist among different countries. Core knowledge is mainly based on the traditional disciplines (such as occupational hygiene, occupational toxicology, ergonomics, epidemiology and biostatistics, relevant legislation, and preventive medicine). General learning objectives should include assessment of the workplace environment, communication and education, legislation, occupational diseases, and relationships between health and work. Core experience, often based on task-based learning, emphasizes the need for assessment of a range of working environments; for surveillance, including the biological monitoring, of workers at risk; for assessment of disability, impairment, and fitness for work; for the clinical ability to recognize occupational diseases; for the formulation of differential diagnosis; and for management of workers developing disease in the course of their employment. New curricular elements (such as management, economics, quality assurance, and marketing) are being introduced in some institutions with the aim of stressing the renewed role of the occupational physician in meeting society and employers' needs. The need to educate and train a professional figure whose competence should allow the delivery of high-quality occupational health services across European Union countries compels the harmonization of the formative process of occupational physicians.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1433-2965
    Keywords: Key words:Bone mineral density (BMD) – Dual-energy X-ray absorptiometry (DXA) – Femoral neck – Hispanic – Lumbar spine – Mexican women
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The aim of this study was to generate standard curves for normal spinal and femoral neck bone mineral density (BMD) in Mexican women using dual-energy X-ray absorptiometry (DXA), to analyze geographic differences and to compare these with “Hispanic” reference data to determine its applicability. This was a cross-sectional study of 4460 urban, clinically normal, Mexican women, aged 20–90 years, from 10 different cities in Mexico (5 in the north, 4 in the center and 1 in the southeast) with densitometry centers. Women with suspected medical conditions or who had used drugs affecting bone metabolism, were excluded. Lumbar spine BMD was significantly higher (1.089 ± 0.18 g/cm2) in women from the northern part of Mexico, with intermediate values in the center (1.065 ± 0.17 g/cm2) and lower values (1.013 ± 0.19 g/cm2) in the southeast (p〈0.0001). Similarly, femoral neck BMD was significantly higher in women from the north (0.895 ± 0.14 g/cm2), intermediate in the center (0.864 ± 0.14 g/cm2) and lower (0.844 ± 0.14 g/cm2) in the southeast part of Mexico (p〈0.0001). Northern Mexican women tend to be taller and heavier than women from the center and, even more, than those from the southeast of Mexico (p〈0.0001). However, these differences in BMD remained significant after adjustment for weight (p〈0.0001). A significant loss (p〈0.0001) in BMD was observed from 40 to 69 years of age at the lumbar spine and up to the eighth decade at the femoral neck. Higher and lower lumbar spine values, as compared with the “Hispanic” population, were observed in Mexican mestizo women from the northern and southeastern regions, respectively. In conclusion, there are geographic differences in weight and height of Mexican women, and in BMD despite adjustment for weight.
    Type of Medium: Electronic Resource
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